The Institute of Cancer Research, London, and science and technology company Merck have renewed their strategic alliance in the discovery and development of new cancer drugs. Scientists in the Centre for Cancer Drug Discovery at The Institute of Cancer Research (ICR) will work with researchers at Merck on a range of related projects, each of which aim to discover and develop new small-molecule inhibitors of an exciting new class of cancer targets...
AMSBIO has published a case study that describes how a team of scientists, led by Dr. Roger Kamm from the Massachusetts Institute of Technology (MIT), has developed a protocol for the fabrication of a 3D microfluidic neuromuscular platform that can be used to model Motor Neuron Diseases (MND’s). Researchers at MIT have developed novel approaches to unravel the pathogenesis of MNDs using CELLBANKER® 1 and STEM-CELLBANKER® cryopreservation media from AMSBIO...
Global sustainable laboratory equipment visionaries, Asynt, have collaborated with Kingston University (London, UK) and renowned worldwide chemical products supplier, Key Organics, to develop an accessible new synthetic compound library. Chemists from the Wren Group at Kingston University (UK) have formed a collaborative relationship with these industry leaders, enabling them to create a novel synthetic compound library....
A new research announcement to leverage the unique environment of the International Space Station (ISS) to advance tissue engineering and biomanufacturing is now open. The ISS National Laboratory® is soliciting concepts for applied research and technology development for regenerative medicine applications seeking to demonstrate space-based manufacturing and production activities for terrestrial applications...
Cormeum Lab Services, a cutting-edge clinical testing laboratory in Louisiana, is using a range of pipetting solutions from INTEGRA Biosciences to streamline its infectious disease testing workflows. The laboratory acquired additional liquid handling instruments to cope with ever growing demand during the COVID-19 pandemic, and these tools are now supporting expansion of its testing capabilities...
A healthy immune system is what defends the body from invaders like bacteria and viruses. But for the elderly and those facing chronic diseases, the immune system can wear down over time. To better understand the relationship between immune aging and how the body heals itself, a team of scientists took their research to new heights by leveraging the International Space Station (ISS) National Laboratory to study microgravity’s effects on immune cell function...
Artificial sweeteners are added to many foods and cosmetic products. As useful as they are in these areas, they pollute wastewater and groundwater. Therefore, powerful LC-MS/MS applications for the most common artificial sweeteners acesulfame, saccharin and cyclamateare essential. Find out more about how to implement an ultra-fast analysis routine in your lab by downloading the application note...
New treatment re-sensitises advanced prostate cancers to treatment by stopping tumours hijacking myeloid white blood cells to help fuel their growth. Prostate cancer’s resistance to treatment can be reversed in some patients by stopping hijacked white blood cells from being ‘pulled into’ tumours, according to new research published in Nature. In an early clinical trial, researchers showed that blocking the messages cancer uses to hijack white blood cells can re-sensitise a subset of advanced prostate cancers to treatment – shrinking tumours or halting their growth...
The Chief Executive of one of Britain’s leading tissue engineering companies has co-authored a book entitled Advances in Cultured Meat Technology that explores the potential of cultured meat production in solving food security challenges and helping to achieve climate targets. With the global population estimated to reach 9 billion by 2050, Professor Che Connon, Chief Executive of the pioneering UK-based clinical and cellular agriculture company 3D Bio-Tissues together with Professor Mark and Dr Chris Bryant...
INTEGRA Biosciences has awarded 31 EVOLVE manual pipettes, GRIPTIPS®pipette tips worth US $1000, and lab accessories to the bioanalytical company DNTOX as part of its recent ‘INTEGRA supports start-ups’ competition, which ran until April 2023. The pipettes will greatly streamline the company’s neurotoxicological hazard assessments, helping to increase its testing capacity and advance research in this vital area...
The Pistoia Alliance, a global, not-for-profit alliance that advocates for greater collaboration in life sciences R&D, is releasing the results of a new global survey conducted in partnership with Open Pharma Research, organizers of the Lab of the Future Congress, examining lab technology investment, barriers, and benefits. The Alliance surveyed 200 experts spanning Europe, the Americas and APAC from its network of members, including lab professionals and R&D experts from top pharma companies, medium enterprises and life science start-ups...
Charles River Laboratories International, Inc. and PathoQuest SAS, a leader in the development and provision of next-generation sequencing (NGS) testing services for biopharmaceuticals, have announced the publication of the results of a seminal study in Vaccine. This unique study demonstrated that PathoQuest’s proprietary, good manufacturing practice (GMP) grade NGS-based assay had a greater capability of detecting viral contaminants when compared to in vivo assays...
Four astronauts ended a six-month science expedition onboard the International Space Station (ISS) with the successful splashdown of the SpaceX Dragon Endeavour spacecraft off the coast of Florida. During their time in space, the crew members worked on dozens of research investigations and technology demonstration projects that were sponsored by the ISS National Laboratory...
The Institute for Research and Innovation in Biomedicine (IRIB) focuses on developing innovative technologies for diagnosing, treating, and preventing diseases. Its research programs are centered around several themes, including cancer, infectious diseases, neurodegenerative diseases, and regenerative medicine. Located in Rouen, France, the IRIB brings together researchers and experts from various fields, including biology, chemistry, physics, and medicine, to collaborate on cutting-edge research projects....
Researchers at the Wellcome Centre for Mitochondrial Research (WCMR), within the Faculty of Medical Sciences at Newcastle University in the UK, have chosen INTEGRA Biosciences’ VOYAGER adjustable tip spacing pipette to support their research on mitochondrial diseases. The multidisciplinary team is using the equipment to streamline various steps in its high throughput screening assays to identify drugs that are capable of rescuing mitochondrial function to improve the quality of life of those living with a mitochondrial condition...
Chromatographic purification on a research scale is a must-have in many areas such as academia and pharmaceutical research. However, this can be very time consuming. Therefore, effective development of the purification method is essential. These guidelines from YMC demonstrate the main steps for an effective purification method development...
Axis Healthcare, a family-run care facility in Oklahoma, has introduced VOYAGER adjustable tip spacing pipettes from INTEGRA Biosciences into its PCR laboratory workflows. These multichannel pipettes offer the laboratory a straightforward and easy-to-use liquid handling solution to provide accurate and high throughput testing as part of a holistic strategy to support patients in overcoming opioid addiction...
A team of scientists, from the University of Bath’s Department of Chemistry and Institute for Sustainability have found a way to create two of the world’s most common painkillers, paracetamol and ibuprofen, out of a compound found in pine trees, which is also a waste product from the paper industry. It is perhaps not widely known that many common pharmaceuticals are manufactured using chemical precursors derived from crude oil, presenting a niche sustainability challenge as the world targets Net Zero...
A new six-month science expedition in low Earth orbit (LEO) begins when four astronauts launch to the International Space Station (ISS) as part of NASA’s SpaceX Crew-7 mission. While onboard the space station, the Crew-7 astronauts, who will be part of Expeditions 69 and 70, will perform a variety of investigations sponsored by the ISS National Laboratory. This 7th rotational crewed mission from SpaceX, which is part of NASA’s Commercial Crew Program, is scheduled to launch from NASA’s Kennedy Space Center in Florida...
Promega scientists contribute to new research to improve precision and efficiency of groundbreaking gene editing technique. A new study published in Nature Communications demonstrates how small molecule inhibitors can be used to improve the precision and efficiency of CRISPR-Cas9 gene editing. The results demonstrate how this groundbreaking technique can be enhanced by using two inhibitors to boost insertion rates and reduce off-target effects...
Growing demand for analytical laboratory services (and the impact of the COVID-19 pandemic) will see the industry grow globally to about $492 million by 2027. Batch Release Testing shows the biggest growth in the market, estimated to increase at 9% Compound Annual Growth Rate (CAGR). To keep up with the expected demand over the next seven years, you’ll need to know all the latest techniques and analytical methods that could affect your SPE workflows. Here, Gilson discuss some of the latest considerations for your SPE processes...
Research labs are complicated environments and it is not always clear what can be done to improve sustainability. To date, most of the discussion around sustainability has focussed on the energy efficiency of instruments and equipment, such as fume hoods and cryogenic freezers. While this is important, it means that things like chemical and solvent selection are overlooked. Here Paul Vanden Branden, Director at SciMed, an exhibitor at Lab Innovations 2023 and member of the show’s advisory board, discusses...