J.G. Finneran Associates is a highly recognized, respected and independent, family-owned and operated glass and plastic manufacturer.
A specialist in chromatography, biotechnology and environmental products which include glass and plastic vials, closures and accessories, the patented 96-Well Multi-Tier™ Micro Plate System and accessories, VOA/EPA vials, and sampling bottles and jars – pre-cleaned and pre-cleaned/certified. Their manufacturing operations located in Vineland, NJ, USA, combine the most modern and highly automated equipment with our own custom designed machinery to handle volume production while maintaining product integrity and the highest quality products in the industry.
Some of the UK’s brightest young scientists will be taking part in the Royal Society of Medicine’s Medical Innovations Summit on Saturday 5 July.
Eighteen-year old twin sisters Ameeta and Aneeta Kumar, winners of the UK Young Scientist of the Year competition, will describe their project to develop a diagnostic tool for identifying cancerous tumours at an early stage of development. Beating off competition from 4,000 other entries, the pair are now both considering a career in medicine. Also in her teens, Amber McCleary will explain how the anti-bacterial and healing properties of the copper-infused pyjamas she and inventor Paula Ward produced last year quite possibly saved the life of a new mother who had acquired MRSA from a caesarean section wound...
AFFiRiS halted clinical progression in Alzheimer patients upon treatment with AD04 in a phase II clinical study
AFFiRiS announced today the results of a phase II study in Alzheimer patients. AFFiRiS' proprietary compound AD04 is the first drug ever to demonstrate clinical and biomarker effects consistent with disease modification in Alzheimer patients. Upon treatment with AD04, effects consistent with disease modification were achieved for at least 18 months in 47 % of treated patients. This beneficial effect was dose dependent and more effective in early disease patients. Furthermore, prevention of hippocampal decline was correlated with the beneficial impact on clinical progression and...
A recently published study has highlighted the economic and clinical benefits of incorporating a near patient nucleic acid amplification test (NAAT) for Chlamydia trachomatis and Neisseria gonorrhoeae into genitourinary medicine clinics.
Sponsored by leading molecular diagnostics company Cepheid, this prospective study estimates savings of up to £11.75m per annum from the adoption of laboratory-standard POC NAATs, such as Cepheid’s Xpert® CT/NG. Recent advances in technology have enabled the latest generation of in-clinic analysers – such as Cepheid’s GeneXpert® series – to offer rapid, PCR-based testing at the point of patient care. This new generation of assays can provide laboratory quality results within...
Anasys Instruments reports on EPFL’s latest research on lysozyme droplets and α-synuclein macromolecular aggregates illustrating application of the nanoscale AFM-IR technique to demonstrate α to β secondary structure transition associated with amyloid formation.
Proteins aggregating into amyloid structures are involved in important neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease. During aggregation, initially monomeric proteins undergo internal structural rearrangement forming amyloid fibrils with a universal cross β -sheet quaternary structure. During fibrillation, several coexisting amyloidogenic species are formed and the study of these species would allow...
EKF Molecular Diagnostics, and GILUPI, an innovator in medical devices for in vivo isolation of rare cells directly from a patient’s blood stream, announce results from collaborative work using the GILUPI CellCollectorTM and EKF Molecular’s PointManTM DNA Enrichment technology.
The first results of the collaboration have successfully demonstrated the detection of gene mutations from as few as three or less cells isolated in a model in vitro system and from the blood of lung cancer patients. PointMan DNA Enrichment was used to detect and analyse cells with known mutation status that had been collected on GILUPI CellCollectors under laboratory conditions. The known mutations were those typically seen in...
EKF Diagnostics, the global diagnostics company, today highlights that the lead scientist working in collaboration with its Kidney Biomarker team to develop tests for progressive Diabetic Kidney Disease (DKD) will receive the 2014 Kelly West Award in Epidemiology at the American Diabetes Association (ADA) 74th Scientific Sessions.
Dr. Andrzej Krolewski, MD, PhD, Head of Section on Genetics and Epidemiology at the Joslin Diabetes Center and Professor of Medicine at Harvard Medical School, receives this eminent award in recognition of his significant contribution to the field of diabetes epidemiology. At the ADA 74th Scientific Sessions (13-17th June, 2014, San Francisco), Dr. Krolewski will also deliver the Kelly West Award lecture...
The Program Committee is pleased to announce the call for papers for the Pittcon 2015 Technical Program.
Abstracts are currently being accepted for contributed oral and poster presentations in areas such as, but not limited to, analytical chemistry, applied spectroscopy, life science, bioanalysis, food science, nanotechnology, environmental science and pharmaceutical. The 2015 committee is especially interested in topics relevant to energy and fuels. Program Chairman Hub MacDonald commented, “Since this year’s conference will be in New Orleans with Louisiana holding the...
It is now possible with gene therapy for patients with haemophilia to be free from severe bleeding in remarkable work that originated in animal studies.
Data about patients who remain free from the need for preventative injections for two years will be presented at the 19th Congress of the European Hematology Association. The understanding of how gene therapy technology might be applied to treat patients with other inherited diseases will also be discussed. Inherited bleeding tendency (haemophilia) can have devastating effects on the lives of patients and, if uncontrolled, can be...
Accelerated Technology Laboratories, Inc. (ATL) will host the fifth in our 2014 series of webcasts on Wednesday, June 18, 2014, to share information on leveraging LIMS as s Software as a Service (SaaS) model.
DATE: Wednesday, June 18, 2014
A hosted LIMS is a great choice for small to medium size organizations that do not have the capital needed for their own servers or the software purchase, or lack an internal IT department to manage a local solution. A hosted solution can allow these organizations to deploy and implement a robust LIMS often more quickly and with less upfront cost as compared to the traditional purchased model...
Read MoreHP D300 Offers Speed and Reliability for Drug Titrations at GSKJun 18, 2014
GlaxoSmithKline’s quest for improved anti-malarial treatments has been revolutionized by the speed and reliability of the HP D300 Digital Dispenser.
The system – distributed by Tecan – has enabled scientists working at GSK’s Malaria Discovery Performance Unit (DPU) in Tres Cantos, Spain, to increase throughput for standard drug titrations and to test additional combinations of candidate compounds. Dr Laura Sanz, an investigator in the Malaria DPU’s Biochemistry and Parasitology Department, explained: “We have been working with the HP D300 since autumn 2012, and...
Work has commenced on the site of the Institute of Translational Medicine Birmingham (ITM).
The world-class clinical research facility, which will be located in the old Queen Elizabeth Hospital, next to the new Queen Elizabeth Hospital Birmingham and the University of Birmingham Medical School, is designed by Glenn Howells Architects. The ITM’s vision is to use pioneering science to accelerate the delivery of personalised healthcare. It aims to cure disease and save lives by applying transformative science and technology and by educating and training the...
Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation has published the results of a new study outlining the simultaneous measurement of protein charge and diffusion interaction parameter (kD) to determine the colloidal stability of two formulations with different long-term stability behavior.
Traditionally, these two properties are measured independently in laborious experiments requiring manual sample preparation and loading. The Möbius® from Wyatt Technology uses massively-parallel phase-analysis light scattering (MP-PALS) in conjunction with an autosampler to automate this combined measurement. The Möbius is therefore an ideal tool for protein characterization and is unique in its ability to provide a complete picture of...
The 4th Annual Next Generation Sequencing Asia Congress is taking place on 7th & 8th October 2014 in Singapore.
It brings together over 175 senior experts to discuss recent developments in sequencing, epigenetics and genomics. Topics covered include next generation sequencing technologies & platforms, plant & animal genomics, clinical applications, cancer research & diagnostics, analytical genomics, bioinformatics & data management. The 4th Annual Next Generation Sequencing Asia Congress will be co-located with the 2nd Annual Single Cell...
Magritek, a leading worldwide provider of compact NMR and MRI instruments, have launched the first six in a series of laboratory experiment manuals to help teach undergraduate students about the practical benefits of using Nuclear Magnetic Resonance, NMR.
In collaboration with the School of Chemical and Physical Sciences at Victoria University of Wellington, Magritek have developed a set of student teaching laboratory manuals. These are aimed at second and third year organic Chemistry labs. Students will use the Spinsolve® benchtop NMR spectrometer to analyse their own samples with simple one- and two-dimensional NMR methods...
Cresset, innovative provider of computational chemistry software and services, is pleased to announce that the Centre for Chemical Biology and Therapeutics (CCBT) at The Institute for Stem Cell Biology and Regenerative Medicine (inStem), a state-of-the-art research institute in Bangalore, India, has taken a three year license for use of Cresset’s Forge and Spark software tools for lead optimization and identification.
The CCBT, which is directed by Prof. Ashok Venkitaraman (University of Cambridge) in an international collaboration between Cambridge and inStem, seeks to pioneer new approaches for chemical biology and therapeutics through the development of new methods for small-molecule drug discovery. Cresset and Forge will be used in the new computational chemistry group in the CCBT. Dr. Kavitha Bharatham, who leads the...
Thermo Fisher Scientific has developed an on-line solid-phase extraction–high-performance liquid chromatography (SPE-HPLC) method combined with ultraviolet (UV) absorbance detection for the simple and sensitive determination of tigecycline in a cell lysate sample.
Application Note 1074:Determination of Tigecycline in a Cell Lysate demonstrates that this approach, performed on a rapid separation LC (RSLC) system controlled by data management software, detects trace amounts of tigecycline in tigecycline-treated cells, concentrations so low that they cannot be assayed using a routine HPLC-UV detection method. The prevalence of multidrug-resistant bacteria in hospitals underscores the need for...
Analytik, leading suppliers of innovative analytical instrumentation, report on research work at the Babraham Institute to study protein microarrays using the GeSiM Nano-Plotter system.
Affinomics is an EC FP7 Collaborative Project set up to initiate the generation of a proteome-wide binder collection. To this end, the project integrates the expertise and technologies available in leading European centres in order to create an efficient pipeline for target and binder production, validation and quality control. It is coordinated by Dr Mike Taussig of the Protein Technology Group at the Babraham Institute near Cambridge...
Scientists at Nuclea Biotechnologies, Inc. and Thermo Fisher Scientific are pooling their expertise to develop novel multiplexed research methods for high-throughput quantification of native insulin and its therapeutic analogs.
Monitoring the levels of these markers may be useful in predicting the response to therapy for Type 2 diabetes. Nuclea has extensive experience in developing and commercializing biomarkers and clinical tests. The Thermo Fisher Scientific Biomarker Research Initiatives in Mass Spectrometry (BRIMS) Center has successfully collaborated with numerous leading clinical researchers to apply mass spectrometry (MS) to biomarker discovery...
The application of molecular technology in clinical diagnosis is a rapidly developing area and is predicted to greatly improve the speed, efficiency and accuracy of diagnostic medicine.
A book looking at the challenges within molecular diagnostics, “Molecular Diagnostics: Current Research and Applications”, edited by Dr Jim Huggett and Dr Justin O’Grady, is published this month by Caister Academic Press. It is essential reading for anyone involved in the development or application of molecular diagnostics and is recommended for all clinical diagnostics laboratories...
EKF Diagnostics, the global diagnostics company, today confirms the growing weight of independent scientific evidence as validation that soluble TNF Receptors 1 and 2 are strong biomarkers of progressive Diabetic Kidney Disease (DKD).
EKF affirms that the markers can be reliably used as diagnostic tests to predict end-stage renal disease (ESRD) - one of the greatest mortality risks in diabetics - up to 10 years in advance. Since signing an exclusive license agreement for this novel kidney biomarker technology with the prestigious Joslin Diabetes Center (Boston, USA) in 2012, EKF Diagnostics has worked in partnership with Joslin and other key diabetic research centers to further...
The Institute of Genetics and Development of Rennes (IGDR), France reports on how, using a VIAFLO 96 handheld multichannel pipette from INTEGRA, they have been able to improve the efficiency and speed with which they replicate yeast strain collections and perform genetic screens in 96 well plates.
The Institute of Genetics and Development of Rennes is one of the major biological research institutes in France. The objective of the IGDR is to develop research of excellence in areas including Genetics, Cell Biology and Developmental Biology. Employing 20 teams of scientists – current research interests at IGDR include investigations into cell polarity, cell cycle, signalisation, membrane trafficking, RNA stability, splicing...
AFFiRiS announced today the results of a phase II study in Alzheimer patients. AFFiRiS' proprietary compound AD04 is the first drug ever to demonstrate clinical and biomarker effects consistent with disease modification in Alzheimer patients. Upon treatment with AD04, effects consistent with disease modification were achieved for at least 18 months in 47 % of treated patients. This beneficial effect was dose dependent and more effective in early disease patients. Furthermore, prevention of hippocampal decline was correlated with the beneficial impact on clinical progression and...
Sponsored by leading molecular diagnostics company Cepheid, this prospective study estimates savings of up to £11.75m per annum from the adoption of laboratory-standard POC NAATs, such as Cepheid’s Xpert® CT/NG. Recent advances in technology have enabled the latest generation of in-clinic analysers – such as Cepheid’s GeneXpert® series – to offer rapid, PCR-based testing at the point of patient care. This new generation of assays can provide laboratory quality results within...
Proteins aggregating into amyloid structures are involved in important neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease. During aggregation, initially monomeric proteins undergo internal structural rearrangement forming amyloid fibrils with a universal cross β -sheet quaternary structure. During fibrillation, several coexisting amyloidogenic species are formed and the study of these species would allow...
The first results of the collaboration have successfully demonstrated the detection of gene mutations from as few as three or less cells isolated in a model in vitro system and from the blood of lung cancer patients. PointMan DNA Enrichment was used to detect and analyse cells with known mutation status that had been collected on GILUPI CellCollectors under laboratory conditions. The known mutations were those typically seen in...
Abstracts are currently being accepted for contributed oral and poster presentations in areas such as, but not limited to, analytical chemistry, applied spectroscopy, life science, bioanalysis, food science, nanotechnology, environmental science and pharmaceutical. The 2015 committee is especially interested in topics relevant to energy and fuels. Program Chairman Hub MacDonald commented, “Since this year’s conference will be in New Orleans with Louisiana holding the...
Data about patients who remain free from the need for preventative injections for two years will be presented at the 19th Congress of the European Hematology Association. The understanding of how gene therapy technology might be applied to treat patients with other inherited diseases will also be discussed. Inherited bleeding tendency (haemophilia) can have devastating effects on the lives of patients and, if uncontrolled, can be...
The system – distributed by Tecan – has enabled scientists working at GSK’s Malaria Discovery Performance Unit (DPU) in Tres Cantos, Spain, to increase throughput for standard drug titrations and to test additional combinations of candidate compounds. Dr Laura Sanz, an investigator in the Malaria DPU’s Biochemistry and Parasitology Department, explained: “We have been working with the HP D300 since autumn 2012, and...
The world-class clinical research facility, which will be located in the old Queen Elizabeth Hospital, next to the new Queen Elizabeth Hospital Birmingham and the University of Birmingham Medical School, is designed by Glenn Howells Architects. The ITM’s vision is to use pioneering science to accelerate the delivery of personalised healthcare. It aims to cure disease and save lives by applying transformative science and technology and by educating and training the...
these two properties are measured independently in laborious experiments requiring manual sample preparation and loading. The Möbius® from Wyatt Technology uses massively-parallel phase-analysis light scattering (MP-PALS) in conjunction with an autosampler to automate this combined measurement. The Möbius is therefore an ideal tool for protein characterization and is unique in its ability to provide a complete picture of...
In collaboration with the School of Chemical and Physical Sciences at Victoria University of Wellington, Magritek have developed a set of student teaching laboratory manuals. These are aimed at second and third year organic Chemistry labs. Students will use the Spinsolve® benchtop NMR spectrometer to analyse their own samples with simple one- and two-dimensional NMR methods...
The CCBT, which is directed by Prof. Ashok Venkitaraman (University of Cambridge) in an international collaboration between Cambridge and inStem, seeks to pioneer new approaches for chemical biology and therapeutics through the development of new methods for small-molecule drug discovery. Cresset and Forge will be used in the new computational chemistry group in the CCBT. Dr. Kavitha Bharatham, who leads the...
Affinomics is an EC FP7 Collaborative Project set up to initiate the generation of a proteome-wide binder collection. To this end, the project integrates the expertise and technologies available in leading European centres in order to create an efficient pipeline for target and binder production, validation and quality control. It is coordinated by Dr Mike Taussig of the Protein Technology Group at the Babraham Institute near Cambridge...
Monitoring the levels of these markers may be useful in predicting the response to therapy for Type 2 diabetes. Nuclea has extensive experience in developing and commercializing biomarkers and clinical tests. The Thermo Fisher Scientific Biomarker Research Initiatives in Mass Spectrometry (BRIMS) Center has successfully collaborated with numerous leading clinical researchers to apply mass spectrometry (MS) to biomarker discovery...
EKF affirms that the markers can be reliably used as diagnostic tests to predict end-stage renal disease (ESRD) - one of the greatest mortality risks in diabetics - up to 10 years in advance. Since signing an exclusive license agreement for this novel kidney biomarker technology with the prestigious Joslin Diabetes Center (Boston, USA) in 2012, EKF Diagnostics has worked in partnership with Joslin and other key diabetic research centers to further...
The Institute of Genetics and Development of Rennes is one of the major biological research institutes in France. The objective of the IGDR is to develop research of excellence in areas including Genetics, Cell Biology and Developmental Biology. Employing 20 teams of scientists – current research interests at IGDR include investigations into cell polarity, cell cycle, signalisation, membrane trafficking, RNA stability, splicing...