Beckman Coulter Life Sciences and IncellDx, Inc. announced today they have signed a distribution agreement which focuses exclusively on clinical researchers in China, Hong Kong and Taiwan working on the Human Papilloma Virus (HPV) and cancer.
The commercial partnership brings the power of multi-parameter flow cytometry to molecular testing, improving workflow while delivering sensitive and highly reliable cell identification. IncellDx’s next generation (3Dx) investigational molecular assay used to quantify HPV E6, E7 mRNA in single cells has been specially optimized to run on Beckman Coulter’s innovative CytoFLEX flow cytometry system.* The high throughput system instrument...
Leading industry experts will meet at the Pharmaceutical Microbiology Conference (20-21 January 2016, Holiday Inn Kensington Forum, London, UK) to discuss the updates in Rapid Microbal Detection Techniques.
Exclusive speech on Bioburen test by Rapid Microbiological Methods will be given by Francesco Boschi, Microbiological Services Manager, GSK Manufacturing S.p.A. where he will present examples of implementation of new technologies for bioburen test. Adrianne Klijn, Group Leader Microbiological and Molecular Analytics, Nestle Research Center will discuss new mechanisms of bacterial detection using sequencing mechanism and give an insight into rapid microbiology sequencing methods.
Cleaver Scientific has supplied a UV Sterilization Cabinet to Touchlight Genetics (Hampton, UK) who had sought a sterile workspace for the preparation of their RNA and DNA samples and templates.
Touchlight Genetics Ltd. is a rapidly expanding UK biotech company that has developed an entirely enzymatic process of DNA synthesis that is fast, efficient and has a yield that can easily meet growing demand for DNA. The company's dbDNA™ expression cassettes eliminate the need for bacterial sequences and antibiotic resistance genes in the production of biological therapies, satisfying stated concerns from the industry’s main...
Laboratory Information Management Systems (LIMS) specialist, Autoscribe Informatics, has published a new case study describing the use of the Matrix Gemini LIMS in a major Radiological, Environmental and Analytical Laboratory.
The laboratory carries out radioanalytical analysis of environmental samples to provide support for characterisation and independent verification surveys. A LIMS was needed to replace its in-house relational database which could no longer be supported. The system was required to handle a large volume of data and perform unique calculations to correct results. In order to facilitate this, ‘custom table mapping’, a standard technology...
The latest revisions to international pharmacopoeia standards for glass pharmaceutical packaging has seen further harmonisation for testing requirements and see a continual increase in the necessity of delamination propensity studies across the pharmaceutical supply-chain, according to independent research and development, consultancy and testing facility, Glass Technology Services Ltd (GTS).
Commenting on the latest revisions to pharmacopoeia test methods for pharmaceutical glassware, including bottles, vials, ampoules, cartridges and syringes, GTS Laboratory Manager Daniel Capon, said: The United States (USP) and European (Ph. Eur.) Pharmacopoeias remain the most widely used in the global market and recent revisions to both monographs continue to harmonise requirements between the two - bringing welcome simplification...
European Committee on Infection Control (EUCIC) is recruiting representatives from European countries to create national committees
ESCMID Study Group for Antibiotic Policies (ESGAP) calls for junior doctors to participate in antibiotic prescription survey for vital research. The European Committee on Antimicrobial Susceptibility Testing (EUCAST), organized by ESCMID and ECDC, has united all European countries behind common antimicrobial breakpoints and methods for susceptibility testing. The website (www.eucast.org) has more than 50,000 visitors per month...
Antibiotic Research UK (ANTRUK), a charity founded in 2014 to save modern medicine from the onslaught of superbugs, is delighted to announce that the Most Reverend & Right Honourable Dr John Sentamu, Archbishop of York has agreed to become the Charity’s Patron.
Superbugs are fast becoming an increasing problem in hospitals and the community as bacteria become increasingly resistant to our existing antibiotics. There is a significant risk that future generations will not enjoy the same benefits of medicine as we do today. All the medical procedures currently taken for granted, for example cancer treatment, open heart surgery, hip and knee replacement and organ transplantation will become much more perilous...
Proprietary technology allows superior LOH detection in challenging samples
Oxford Gene Technology (OGT), The Molecular Genetics Company, has entered into a deal with Baylor Miraca Genetics Laboratories (BMGL), licensing the use of OGT’s proprietary single nucleotide polymorphism (SNP) array probe technology. This novel technology overcomes the limitations of restriction enzyme-based SNP probe approaches previously employed at BMGL for loss of heterozygosity (LOH) detection, allowing accurate array-based analysis of low...
Analytik, leading suppliers of innovative analytical instrumentation, report on BHR Group using the Microfluidics M-110P for the DOMINO project to study the break-up of silica particle clusters.
BHR Group is an independent research, consultancy and testing company based on the prestigious Cranfield University campus for over 60 years. They specialise in the core skills of fluid dynamics, process scale-up, mixing and dispersion processes; physical and computational modelling, materials interaction, computer aided engineering (CAE), engineering mechanics, chemical behaviour and numerical modelling in the areas of chemical...
Protagen AG,a leading specialist in the development of novel diagnostic tests and companion diagnostics in the autoimmune field, and Mikrogen GmbH, the European market leader in Lyme disease diagnostics, agreed on a co-development program for a new diagnostic assay to distinguish between previously infected, seropositive individuals, from newly infected patients with active Lyme disease.
The agreement builds on a previous research collaboration between both companies and the results obtained using the proprietary SeroTag® technology developed by Protagen. "Finding potential diagnostic biomarkers indicative of Lyme disease activity would be a breakthrough for diagnostics and therapy," explains Dr. Erwin Soutschek, founder and CEO of Mikrogen. "Employing the technology of Protagen, we have identified a...
IDT enables insightful NGS results in clinical and companion diagnostics research, every time
Integrated DNA Technologies (IDT), introduces its new xGen® Exome Research Panel v1.0 for insightful analysis of the human exome via next generation sequencing. A total of 429,826 probes span 39 Mb of the human genome, providing deep and uniform coverage of 19,396 genes. This leads scientists directly to relevant mutations, aiding advances in clinical and companion diagnostics research. By using the xGen Exome Research Panel with xGen...
Natural stones are considered the oldest building materials of mankind.
Due to the diversity of the basic building blocks and minerals, they are considered a durable building material with their superior aesthetic and robust structural-physical characteristics. With risen environmental pollution worldwide in the last centuries and the associated weather factors, the damage to the natural stones and therefore the damage to historic basic structures of buildings also increased. But in fact, after an inspection is the...
Magritek, a leading provider of compact NMR and MRI instruments, continue their leadership position in the establishment of teaching NMR at the undergraduate level with their Spinsolve benchtop NMR spectrometer through the launch of a series of informative videos.
Giving undergraduates the opportunity to get hands-on use of advanced analytical tools such as NMR is a driver for the analytical instrument industry. Benchtop mass spectrometers are now well accepted and the last two years have witnessed the take-off of NMR systems like the Magritek Spinsolve, the fastest benchtop NMR spectrometer. In past years, NMR has been a technique restricted to specially equipped laboratories with highly...
A joint study carried out by Freeman Technology and Gerteis Maschinen + Processengineering AG, a leading provider of roller compactors, provides examples of how the FT4 Powder Rheometer® can be used for fast and effective process optimisation and efficient manufacture.
Results from a series of collaborative experiments show that dynamic powder properties measured with the FT4 Powder Rheometer® reliably detect and quantify the effect of changing compactor operating parameters. Such correlations make it quicker and easier to establish optimal conditions for producing granules that meet defined performance targets from any given feed. Faster optimisation and responsive process control help to drive up manufacturing efficiency, even in the event of...
Accurate and prompt diagnoses of Acute Lower Respiratory Tract Infections (LRTIs) is vital to ensure correct treatment plans are in place to improve patient management.
Immunosuppressed and paediatric patients are especially susceptible to severe disease progression, with sometimes fatal consequences. Dr Marcus Panning, physician and medical virologist, at The University Medical Centre Freiburg, has selected the Fast-track diagnostics Respiratory pathogens 21 assay to detect LRTIs and effectively diagnose vulnerable patients. Dr Panning sees a large proportion of patients in the immunosuppressed and paediatric patient groups. His laboratory...
Presents data on factors that affect the sensitivity of ADCC assays and discusses how to optimise methodology
Sartorius Stedim Biotech (SSB) BioOutsource today announced a new paper entitled, ‘As easy as ADCC’ has been published in the respected journal, European Biopharmaceutical Review. The article outlines the factors affecting the use of antibody-dependent cell-mediated cytotoxicity (ADCC) assays and discusses when to use different types of ADCC assays to guide the design of biosimilar drugs and determine comparability...
Clinicians from the University of Leicester and Leicester’s Hospitals lead an international clinical trial for patients with blood cancer
‘This drug has changed patients’ lives; from desperate and tired they are now leading a normal and really active life. This is hugely rewarding and encouraging.’ Dr Harriet Walter, University of Leicester Researchers from the University of Leicester and Leicester’s Hospitals have announced a breakthrough advance in the results of the world-first clinical trial with actual patients of a new drug to treat particular blood cancers....
Chromatrap®, a business unit of Porvair Sciences, has developed a new protocol that further extends the many advantages of its popular Chromatin Immunoprecipitation Sequencing (ChIP-seq) assay kits.
Key developments for the Chromatrap® ChIP-seq kit (version 1.2) include high quality chromatin can now be achieved via sonication or enzymatic digestion ; high and low abundant enrichment is possible from small chromatin samples ; improved antibody binding ; greater chromatin loading flexibility and the ability to use increased slurry volumes for difficult samples. Chromatrap’s® ChIP-seq kit uses solid state technology...
Chromatography Resins Market in Drug Discovery by Technique (Ion Exchange, Affinity (Protein A, G & L), Hydrophobic Interaction, Size Exclusion, Multi Modal and Others) & Geography - Global Market Trends & Forecasts to 2020
The market for chromatography resins in drug discovery application is estimated at $238.07 Million in 2014 and is projected to grow at a CAGR of 7.0% between 2015 and 2020. The chromatography resins for drug discovery can be made of natural polymers, synthetic polymers or inorganic materials with ligands attached to them. This report on chromatography resins market in drug discovery covers all major regions such as...
Scientists have developed a blood test that can identify key mutations driving resistance to a widely used prostate cancer drug, and identify in advance patients who will not respond to treatment.
The new research paves the way for information from a blood test to inform prostate cancer treatment in future, with only those patients whose cancers are free of resistance mutations taking the drug, abiraterone. The study is also a proof of principle that tests for cancer DNA in the bloodstream can be used to detect drug resistance mutations – allowing patients who will not benefit from one drug to be given an alternative treatment instead...
Inward investment into the knowledge economy sees more than £1.5million go to pioneering work that impacts on health
The University of Leicester has been awarded over £1.5million in order to advance knowledge and understanding in three key areas that impact on health. The funding has come from the Biotechnology and Biological Sciences Research Council (BBSRC), which leads world-class 21st century bioscience, promoting innovation in the bioeconomy and realising benefits for society within and beyond the UK. BBSRC support around 1600 scientists...
Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their temperature controlled stages applied to CLEM and fluorescence microscopy to assist in endocytic sorting in the School of Biochemistry at the University of Bristol.
Dr Paul Verkade is a Reader in Cell Imaging in the School of Biochemistry at the University of Bristol where he also heads the Electron Microscopy unit of the Wolfson Bioimaging Facility. His current research focus is to develop techniques and tools for the use of Correlative Light Electron Microscopy (CLEM) studying endocytic sorting. Dr. Verkade is currently chair of the Electron Microscopy section of the Royal Microscopy Society and chair of...
The commercial partnership brings the power of multi-parameter flow cytometry to molecular testing, improving workflow while delivering sensitive and highly reliable cell identification. 
Exclusive speech on Bioburen test by Rapid Microbiological Methods will be given by Francesco Boschi, Microbiological Services Manager, GSK Manufacturing S.p.A. where he will present examples of implementation of new technologies for bioburen test. Adrianne Klijn, Group Leader Microbiological and Molecular Analytics, Nestle Research Center will discuss new mechanisms of bacterial detection using sequencing mechanism and give an insight into rapid microbiology sequencing methods.
Touchlight Genetics Ltd. is a rapidly expanding UK biotech company that has developed an entirely enzymatic process of DNA synthesis that is fast, efficient and has a yield that can easily meet growing demand for DNA. The company's dbDNA™ expression cassettes eliminate the need for bacterial sequences and antibiotic resistance genes in the production of biological therapies, satisfying stated concerns from the industry’s main...
The laboratory carries out radioanalytical analysis of environmental samples to provide support for characterisation and independent verification surveys. A LIMS was needed to replace its in-house relational database which could no longer be supported. 
Commenting on the latest revisions to pharmacopoeia test methods for pharmaceutical glassware, including bottles, vials, ampoules, cartridges and syringes, GTS Laboratory Manager Daniel Capon, said: The United States (USP) and European (Ph. Eur.) Pharmacopoeias remain the most widely used in the global market and recent revisions to both monographs continue to harmonise requirements between the two - bringing welcome simplification...
Superbugs are fast becoming an increasing problem in hospitals and the community as bacteria become increasingly resistant to our existing antibiotics. There is a significant risk that future generations will not enjoy the same benefits of medicine as we do today. All the medical procedures currently taken for granted, for example cancer treatment, open heart surgery, hip and knee replacement and organ transplantation will become much more perilous...
Oxford Gene Technology
BHR Group
The agreement builds on a previous research collaboration between both companies and the results obtained using the proprietary SeroTag
Integrated DNA Technologies (IDT), introduces its new 
Due to the diversity of the basic building blocks and minerals, they are considered a durable building material with their superior aesthetic and robust structural-physical characteristics. With risen environmental pollution worldwide in the last centuries and the associated weather factors, the damage to the natural stones and therefore the damage to historic basic structures of buildings also increased. But in fact, after an inspection is the...
Giving undergraduates the opportunity to get hands-on use of advanced analytical tools such as NMR is a driver for the analytical instrument industry. Benchtop mass spectrometers are now well accepted and the last two years have witnessed the take-off of NMR systems like the Magritek Spinsolve, the fastest benchtop NMR spectrometer. In past years, NMR has been a technique restricted to specially equipped laboratories with highly...
Results from a series of collaborative experiments show that dynamic powder properties measured with the FT4 Powder Rheometer® reliably detect and quantify the effect of changing compactor operating parameters. Such correlations make it quicker and easier to establish optimal conditions for producing granules that meet defined performance targets from any given feed. Faster optimisation and responsive process control help to drive up manufacturing efficiency, even in the event of...
Immunosuppressed and paediatric patients are especially susceptible to severe disease progression, with sometimes fatal consequences. Dr Marcus Panning, physician and medical virologist, at The University Medical Centre Freiburg, has selected the Fast-track diagnostics Respiratory pathogens 21 assay to detect LRTIs and effectively diagnose vulnerable patients. 
Sartorius Stedim Biotech (SSB) BioOutsource today announced a new paper entitled, ‘As easy as ADCC’ has been published in the respected journal, European Biopharmaceutical Review. The article outlines the factors affecting the use of antibody-dependent cell-mediated cytotoxicity (ADCC) assays and discusses when to use different types of ADCC assays to guide the design of biosimilar drugs and determine comparability...
‘This drug has changed patients’ lives; from desperate and tired they are now leading a normal and really active life. This is hugely rewarding and encouraging.’ Dr Harriet Walter, University of Leicester Researchers from the University of Leicester and Leicester’s Hospitals have announced a breakthrough advance in the results of the world-first clinical trial with actual patients of a new drug to treat particular blood cancers....
Key developments for the Chromatrap® ChIP-seq kit (version 1.2) include high quality chromatin can now be achieved via sonication or enzymatic digestion ; high and low abundant enrichment is possible from small chromatin samples ; improved antibody binding ; greater chromatin loading flexibility and the ability to use increased slurry volumes for difficult samples. 
The market for chromatography resins in drug discovery application is estimated at $238.07 Million in 2014 and is projected to grow at a CAGR of 7.0% between 2015 and 2020. The chromatography resins for drug discovery can be made of natural polymers, synthetic polymers or inorganic materials with ligands attached to them. This report on chromatography resins market in drug discovery covers all major regions such as...
The new research paves the way for information from a blood test to inform prostate cancer treatment in future, with only those patients whose cancers are free of resistance mutations taking the drug, abiraterone. 
Dr Paul Verkade is a Reader in Cell Imaging in the School of Biochemistry at the University of Bristol where he also heads the Electron Microscopy unit of the Wolfson Bioimaging Facility. His current research focus is to develop techniques and tools for the use of Correlative Light Electron Microscopy (CLEM) studying endocytic sorting. Dr. Verkade is currently chair of the Electron Microscopy section of the Royal Microscopy Society and chair of...