Leica Biosystems, a global leader in anatomic pathology solutions and workflow automation, and Advanced Cell Diagnostics, Inc. (ACD), a world leader in RNA biomarker analysis for precision medicine, today announced a comprehensive partnership to develop and commercialize tissue-based diagnostic tests based on ACD's RNAscope in situ hybridization (ISH) assays on Leica Biosystems' BOND clinical advanced staining instruments.
The agreement supports Leica Biosystems' development and commercialization of fully automated RNAscope-based companion diagnostic (CDx) tests in partnership with biopharmaceutical companies. The combination of ACD's RNAscope technology with Leica Biosystems' fully automated pathology solutions allows companies and laboratories in clinical markets to integrate the power of new RNA-based biomarker tests into the...
Dr Alessio Ciulli of the University of Dundee has been named the winner of a major award from the Royal Society of Chemistry.
Dr Ciulli, from the University’s School of Life Sciences, has been named joint winner of the Capps Green Zomaya Memorial Award by the RSC. The award recognises outstanding work in medicinal or computational medicinal chemistry and is given to `an individual judged to have made an important contribution to the discovery or development of new medicines’, with nominations open to candidates up to the age of 40. The award has been given to Dr Ciulli in recognition of...
‘This basic research set the grounds for structure-based drug design approaches that could be beneficial for cancer treatments’ Dr. Cyril Dominguez, University of Leicester
A team from the University of Leicester has for the first time published a detailed description of a protein linked to many types of cancer. The lab-based study from the Department of Molecular and Cell Biology now provides an opportunity for scientists to develop drugs to target this protein. Dr Cyril Dominguez who led the work at Leicester said: “My research field is structural biology. The proteins that we have studied, called...
Markes International (Llantrisant, UK) has announced that it will be giving a short course on ambient air monitoring at Pittcon 2016 (in Atlanta, Georgia, USA), and present several technical papers, rather than having an exhibition booth on the tradeshow floor.
The half-day course, entitled “Ambient air monitoring: What are the right tools for the job?” will take place in the morning of Thursday, March 10th and is aimed at analysts, test laboratories, environmental consultants, regulators, universities and environmental representatives from industry. Registration for the course is via the Pittcon website.The course consists of modules on: Real-world analysis: Test lab perspective...
Prior Scientific reports that its OptiScan® controller together with associated microscope stage and focus motor have been used to create stunning artistic designs.
Using this equipment, Richard Weston, a former Professor of Architecture at Cardiff University (UK) has acquired high magnification images of minerals, such as agate, fluorite, and calcite, to produce unique designs for a range of products including scarves, glass panels, and in one case a facade for a three story house. Asked about his novel use of the Prior stage and stepper motor, Richard Weston commented...
Pharma and cosmetics multinational selects BioAscent as central hub for storage and logistics of extensive plant natural extracts collection
BioAscent Discovery, announces a new collaboration with pharmaceutical and cosmetics multinational, Pierre Fabre, as part of an open innovation initiative promoting the use of natural products in life sciences. Pierre Fabre’s library of ca. 15,000 plant extracts is the largest private collection of its type in the world. BioAscent’s state-of-the-art compound management and logistics facility is ideally placed to share out such an extract...
EATRIS (European Infrastructure for Translational Medicine) has today announced a partnership with Dutch Arthritis Foundation Reumafonds, to advance translational research for rheumatic disorders.
The announcement follows a successful pilot, which saw the two organisations join under the EATRIS Inside model, which offers funders access to translational research expertise and facilities to support the optimisation of their research portfolio. As part of the new collaboration, EATRIS will support Reumafonds with their projects that seek to translate new scientific insights into promising medicines and diagnostics for a wide range of...
Veolia Water Technologies has released a new video showing how their ultrapure water technology is helping cutting edge research at the National Graphene Institute.
The video includes material provided by The University of Manchester, in particular a fascinating introduction to graphene, the most exciting material of the 21st century, its almost limitless potential and the amazing research facility that is the National Graphene Institute. Graphene is only a single molecule thick and research at this level requires water of ultimate purity - well in advance of the current highest standards for semiconductor...
Avere FXT Series Edge Filers and Flash Capabilities Vault Space Data onto the AWS Cloud
Avere Systems, a leading provider of enterprise storage for the hybrid cloud, today announced that NASA has selected Avere to help consolidate legacy storage and move many of its datasets to the Amazon Web Services (AWS) Cloud. Avere will be supporting the Ames Research Center, NASA’s Silicon-Valley field center, which has led NASA in conducting world-class research and development. Breakthrough research conducted at the...
Magritek, a leading provider of compact NMR and MRI instruments, report on the use of their Spinsolve Benchtop NMR spectrometer in the Chemistry Department of Samford University located in Birmingham, Alabama.
It is being applied in research in the areas of organic synthesis, reaction methodology and medicinal chemistry. Dr Paul Wiget is an assistant professor of chemistry at Samford University in Birmingham, Alabama. He first became interested in the Spinsolve instrument when he began interviewing for his current position knowing that his research interests would require a work-around for the lack of a local high-field NMR. Spinsolve, as a...
Plasma cells play a key role in our immune system.
Now scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria, and at the Walter and Eliza Hall Institute (WEHI) in Melbourne, Australia, succeeded in characterizing a central regulator of plasma cell function. The results of both teams are published in two back-to-back papers in "Nature Immunology" today. Our environment teems with microorganisms and viruses that are potentially...
A Cancer Research facility in Hertfordshire is among a growing contingent of clinical trial sites that have adopted asepticSU™ single use fluid path technology from Watson-Marlow Fluid Technology Group.
Used in conjunction with two Flexicon FP50 automated filling and stoppering machines, asepticSU™ has helped the Biotherapeutics Development Unit (BDU) at South Mimms to eliminate the need for cleaning validation and simplify traceability of applied product contact components. The BDU is a modern, MHRA licensed, fully GMP-compliant, 2000 m² facility that is engaged in the process development and production of novel Investigational Medicinal Products (IMPs) for...
Deben, a leading provider of in-situ testing stages together with innovative accessories and components for electron microscopy, reports on the use of a Microtest tensile stage in the Institute of Photonics & Quantum Sciences at Heriot-Watt University, Edinburgh.
It is being used for stress analysis studies of ceramics and engineering plastics. Dr Peter Schemmel is a postdoctoral researcher in Applied Photonics at Heriot-Watt University. He is part of the team at the Institute of Photonics and Quantum Sciences in a group which focuses on stress analysis in ceramics and engineering plastics. They are particularly interested in ceramic thermal barrier coatings used on aeroplane engine turbine blades or...
This upcoming webinar hosted by Oxford Global will provide an insight on the Advances In Inhaled Insulin Research on Wednesday 17th February 2016 | 3 pm GmT.
Inhalable insulin research represents a very exciting area of the inhalation drug delivery market. Inhaled insulin has evoked a lot of interest recently and shows a great promise in treating diabetes. Oxford Global’s free webinar offer attendees the unique opportunity to hear recent advancements in inhalable insulin research as well as aerosol technology. Through the interactive Q&A session, attendees will also...
Synbiosis,a long-established, expert manufacturer of automated microbiological systems, is delighted to announce a new paper entitled, ‘Evaluation of heterotrophic plate and chromogenic agar colony counting in water quality laboratories’ has been published in the peer-reviewed journal, Methods X.
The paper details how scientists at the Australian Water Quality Centre (AWQC) have for the first time independently validated that results from the ProtoCOL 3 automated colony counter are as accurate as manual colony counting. The article describes how microbiologists at AWCQ, a leading NATA (National Association of Testing Authorities) accredited water testing laboratory in Adelaide, Australia cultured microorganisms isolated from...
Cancers evolve over time in patterns governed by the same natural laws that drive physical and chemical processes as diverse as the flow of rivers or the brightness of stars, a new study reports.
Researchers believe that in the future, they could predict how a cancer will grow and develop by applying natural laws to single genetic snapshots taken from a cancer. The intriguing research raises the possibility that doctors could take clinical decisions on how an individual patient’s cancer will change, and what treatments should be used, by applying mathematical formulas to tumour biopsies. Scientists at The Institute of...
In preparation for the trial Myeloma UK worked closely with Takeda initiating a first-of-its kind pilot, by going jointly to NICE to seek scientific advice on both TOURMALINE-MM1 and MUK eight
This is the first time a medical research charity and a pharmaceutical company have gone jointly to NICE Scientific Advice. Myeloma UK announces that MUK eight, a Phase II trial of the oral proteasome inhibitor, ixazomib, is now open for recruitment. MUK eight is a randomised Phase II trial comparing the novel oral proteasome inhibitor ixazomib in combination with cyclophosphamide and dexamethasone, against a combination of cyclophosphamide and dexamethasone in relapsed and/or refractory myeloma patients. This is the eighth trial to be set up...
Synpromics Ltd, a leading synthetic biology company, and The Cell Therapy Catapult, the UK organisation accelerating the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announce the launch of a collaboration to remove a major barrier to the development of the cell and gene therapy industry by reducing the cost and increasing the scale and efficiency of viral vector manufacturing.
The collaboration will use Synpromics' synthetic promoter design technology, and the Cell Therapy Catapult's flexible manufacturing platform to create stable producer cell lines for the high titre and large scale manufacture of viral vectors. The work will be part funded by a £2m grant from Innovate UK, the UK’s innovation agency. Viral vectors are a crucial tool needed to modify patient’s cells to create a therapeutic effect...
A Dolomite microfluidic system is helping Dr Samar Damiati, Assistant Professor in the Biochemistry Department at King Abdulaziz University in Saudi Arabia, perform drug encapsulation studies.
She explained: “My work is mainly focused on using different polymers, particularly PLGA – poly(lactic-co-glycolic acid) – for drug encapsulation, generating monodisperse particles for further investigation. I use a Dolomite system for this purpose, preparing particles on an almost daily basis, and find it very straightforward.” “The drugs I am currently working with are hydrophobic and need to be encapsulated in suitable...
Analytik, leading suppliers of innovative analytical instrumentation, report on Scott Bader's characterisation of conventional and inverse emulsions using the CPS Disc Centrifuge UHR.
Scott Bader is a multinational chemical company with production and laboratory facilities around the world. Their Speciality Polymers Group is based at Wollaston near Wellingborough. Here the group develops conventional and inverse emulsion products for a variety of industrial applications, as well as providing technical support for production. The most familiar type of emulsion is probably the oil in water emulsion...
The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, the University of Birmingham and Cancer Research Technology, the commercialisation arm of Cancer Research UK, announces today the launch of a collaboration to develop a new immuno-oncology cellular therapy based on gene modifying T cells to target solid tumours.
The project is aimed at translating an academic discovery programme funded by Cancer Research UK and developed by Dr Steven Lee and Prof Roy Bicknell at the University of Birmingham into a commercially viable cell therapy.The collaborating partners have launched a new company, Chimeric Therapeutics Ltd. This new company will hold all future IP rights to the resultant discoveries. The project is based on a new...
The agreement supports Leica Biosystems' development and commercialization of fully automated RNAscope-based companion diagnostic (CDx) tests in partnership with biopharmaceutical companies. The combination of ACD's RNAscope technology with Leica Biosystems' fully automated pathology solutions allows companies and laboratories in clinical markets to integrate the power of new RNA-based biomarker tests into the...
Dr Ciulli, from the University’s School of Life Sciences, has been named joint winner of the Capps Green Zomaya Memorial Award by the RSC. The award recognises outstanding work in medicinal or computational medicinal chemistry and is given to `an individual judged to have made an important contribution to the discovery or development of new medicines’, with nominations open to candidates up to the age of 40. The award has been given to Dr Ciulli in recognition of...
A team from the University of Leicester has for the first time published a detailed description of a protein linked to many types of cancer. The lab-based study from the Department of Molecular and Cell Biology now provides an opportunity for scientists to develop drugs to target this protein. Dr Cyril Dominguez who led the work at Leicester said: “My research field is structural biology. The proteins that we have studied, called...
The half-day course, entitled “Ambient air monitoring: What are the right tools for the job?” will take place in the morning of Thursday, March 10th and is aimed at analysts, test laboratories, environmental consultants, regulators, universities and environmental representatives from industry. Registration for the course is via the Pittcon website.The course consists of modules on: Real-world analysis: Test lab perspective...
Using this equipment, Richard Weston, a former Professor of Architecture at Cardiff University (UK) has acquired high magnification images of minerals, such as agate, fluorite, and calcite, to produce unique designs for a range of products including scarves, glass panels, and in one case a facade for a three story house. 
BioAscent Discovery, announces a new collaboration with pharmaceutical and cosmetics multinational, Pierre Fabre, as part of an open innovation initiative promoting the use of natural products in life sciences. Pierre Fabre’s library of ca. 15,000 plant extracts is the largest private collection of its type in the world. BioAscent’s state-of-the-art compound management and logistics facility is ideally placed to share out such an extract...
The announcement follows a successful pilot, which saw the two organisations join under the EATRIS Inside model, which offers funders access to translational research expertise and facilities to support the optimisation of their research portfolio. 
The video includes material provided by The University of Manchester, in particular a fascinating introduction to graphene, the most exciting material of the 21
Avere Systems
It is being applied in research in the areas of organic synthesis, reaction methodology and medicinal chemistry. 
Now scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria, and at the Walter and Eliza Hall Institute (WEHI) in Melbourne, Australia, succeeded in characterizing a central regulator of plasma cell function. 
Used in conjunction with two Flexicon FP50 automated filling and stoppering machines, asepticSU™ has helped the Biotherapeutics Development Unit (BDU) at South Mimms to eliminate the need for cleaning validation and simplify traceability of applied product contact components. The BDU is a modern, MHRA licensed, fully GMP-compliant, 2000 m² facility that is engaged in the process development and production of novel Investigational Medicinal Products (IMPs) for...
It is being used for stress analysis studies of ceramics and engineering plastics. 
Inhalable insulin research represents a very exciting area of the inhalation drug delivery market. Inhaled insulin has evoked a lot of interest recently and shows a great promise in treating diabetes. Oxford Global’s free webinar offer attendees the unique opportunity to hear recent advancements in inhalable insulin research as well as aerosol technology. Through the interactive Q&A session, attendees will also...
The paper details how scientists at the Australian Water Quality Centre (AWQC) have for the first time independently validated that results from the ProtoCOL 3 automated colony counter are as accurate as manual colony counting. The article describes how microbiologists at AWCQ, a leading NATA (National Association of Testing Authorities) accredited water testing laboratory in Adelaide, Australia cultured microorganisms isolated from...
Researchers believe that in the future, they could predict how a cancer will grow and develop by applying natural laws to single genetic snapshots taken from a cancer. 
This is the first time a medical research charity and a pharmaceutical company have gone jointly to NICE Scientific Advice. Myeloma UK announces that MUK eight, a Phase II trial of the oral proteasome inhibitor, ixazomib, is now open for recruitment. MUK eight is a randomised Phase II trial comparing the novel oral proteasome inhibitor ixazomib in combination with cyclophosphamide and dexamethasone, against a combination of cyclophosphamide and dexamethasone in relapsed and/or refractory myeloma patients. This is the eighth trial to be set up...
The collaboration will use Synpromics' synthetic promoter design technology, and the Cell Therapy Catapult's flexible manufacturing platform to create stable producer cell lines for the high titre and large scale manufacture of viral vectors. The work will be part funded by a £2m grant from Innovate UK, the UK’s innovation agency. 
She explained: “My work is mainly focused on using different polymers, particularly PLGA – poly(lactic-co-glycolic acid) – for drug encapsulation, generating monodisperse particles for further investigation. I use a Dolomite system for this purpose, preparing particles on an almost daily basis, and find it very straightforward.” 
Scott Bader is a multinational chemical company with production and laboratory facilities around the world. Their Speciality Polymers Group is based at Wollaston near Wellingborough. Here the group develops conventional and inverse emulsion products for a variety of industrial applications, as well as providing technical support for production. The most familiar type of emulsion is probably the oil in water emulsion...