Researchers at BRGM (the French Geological Survey in Orleans, France) study the physical, chemical, and structural properties of minerals. BRGM is a public agency which produces and disseminates geological information for government departments, foreign countries, industry and academic research in France and across the world.
They use a co-located SEM-Raman system from Renishaw to provide comprehensive in situ sample characterisation. Dr Guillaume Wille works in the Mineral Physicochemical and Textural Characterization Unit. In describing the analysis methods used at BRGM, Dr Wille said, “Numerous techniques are used, like infrared spectroscopy, X-ray diffraction, electron microscopy and microanalyses....
JPK Instruments works closely with users at the University of Sheffield where their NanoWizard® AFM systems are being used to further understand soft matter and biological systems at the molecular scale in the Hobbs SPM Group in the Department of Physics.
Dr Nic Mullin is a senior experimental officer in the SPM Group of Professor Jamie Hobbs in the Department of Physics & Astronomy at the University of Sheffield. His research is based around instrument development for scanning probe microscopy for the study of soft matter and biological systems at the molecular scale....
CHROMSOC’S SPRING SYMPOSIUM 2017 on Supercritical Fluid & Ultra-High PerformanceChromatography 15th,16th & 17th May 2017
This symposium will feature oral presentations by leading practitioners of SFC and uHPLC. The latest innovations and applications will be described and the lectures will be augmented and supported by a comprehensive table top exhibition of instrumentation and consumables. Poster presentations will also be invited.
Medical Research Council-funded University of Leicester study shows folinic acid can protect neurons in fruit flies
People with certain forms of early-onset Parkinson’s disease could potentially benefit from taking a medication used to treat certain forms of cancer, according to new research by University of Leicester scientists and funded by the Medical Research Council. The study, which has been published in Science Matters, suggests that folinic acid, which is used in medications to treat bowel cancer, can also protect neurons....
Rainin electronic pipettes are helping California-based Clarient Diagnostic Services, Inc. to provide cancer diagnostic testing.
Flow cytometry supervisor Brian Ngo explained: “Our laboratory uses flow cytometry to detect specific biomarkers that help to diagnose leukaemia, and this involves pipetting microliter volumes of antibodies and samples. When you are doing a lot of pipetting, user comfort is very important and so we decided to invest in electronic – rather than manual – pipettes....
The Agrihealth Group of companies, a leading provider of services that directly support the agricultural and food production industries across a number of countries, has purchased a Matrix Gemini LIMS (Laboratory Information Management System) from Autoscribe Informatics.
The LIMS will be used by the Group’s veterinary laboratory. Agrihealth veterinary laboratory is a busy facility based in County Monaghan, Ireland and specialises in the analysis of various types of agricultural and food samples. Much of the analysis carried out is for salmonella and campylobacter for the poultry industry....
Getting a bad night’s sleep could be increasing some people’s likelihood of becoming obese.
According to a study led by the University of Glasgow, and published today in the American Journal of Clinical Nutrition (AJCN), abnormal sleeping habits increase the risk of obesity for those who are genetically predisposed to being overweight. The findings, based on data from the UK Biobank, emphasise that while genetics have a large role to play in obesity, lifestyle also plays an important role....
ERT, a global data and technology company that minimizes risk and uncertainty in clinical trials, today announced that Premier Research, a leading clinical development service provider, has selected ERT’s Trial Oversight suite as its trial management solution.
Clinical trials are becoming increasingly complex, due in part to an array of circumstances including the use of multiple data capture modalities and the need to evaluate more study endpoints than ever before. Additionally, global trials continue to be managed by a growing number of stakeholders, which heightens risks and uncertainties....
Interested in LC applications for caffeine, cannabinoids, catecholamines and cytotoxic agents? Or maybe in anyone of 1000’s of other analytes from amino acids to vitamins?
Advanced Chromatography Technologies (ACT) Limited have recently published a new and comprehensive LC Applications Guide which brings together a huge range of latest LC and LC-MS applications from fields including Clinical, Forensic & Bioanalysis, Environmental, Food & Beverage, Pharmaceutical, LC-MS and more....
Fujitsu, Insight Centre for Data Analytics and Systems Biology Ireland partner to develop an automated engine for predicting phosphorylation reactions, important building blocks of cellular signalling networks that can be used for developing new cancer therapies
Recent biomedical research shows that many serious diseases – in particular cancer – are caused by persistent disruptions of cellular communication processes. These processes use a biochemical reaction called phosphorylation to control the information flow. This biochemical computer is faulty in cancer, and drugs that block rogue phosphorylation reactions have proven effective cancer treatments....
Precision NanoSystems is helping scientists to push the boundaries of neuroscience research with a range of efficient and easy-to-use primary cell transfection kits.
Combining user-friendly NanoAssemblr™ microfluidics systems with advanced nanoparticle technology, the company has developed the Neuro9™, Astro9™ and iNeuro9™ non-viral gene transfection kits to allow rapid and easy knockdown or expression of genes in primary cells, both in vitro and in vivo....
Read MoreMerz Outsources its Compound Management to BioAscentMar 28, 2017
BioAscent supplies screening plates on demand to provide flexible and cost-effective management of solid and liquid compounds
BioAscent Discovery and Merz Pharmaceuticals GmbH, part of the Merz Pharma Group, have entered into a Master Service Agreement (MSA), under which BioAscent provides a comprehensive outsourced compound management service for a significant part of Merz Pharmaceutical’s compound collection, in both solid and liquid forms....
University of Leicester leads study into cause of airway narrowing in cases of asthma
Improved treatments for people with severe asthma are a ‘step closer’ after a research team led by the University of Leicester identified a breakthrough in the cause of airway narrowing. Scientists have, for the first time, discovered that an active form of a key protein, HMGB1, is increased and related to narrowing of the airway in people with severe asthma...
We are delighted to have successfully completed the installation of an Edinburgh Instruments FIRL100 CO2/ FIR (THz) Laser system at Dresden High Magnetic Field Laboratory (HLD) Helmholtz-Zentrum Dresden-Rossendorf (HZDR).
The FIRL-100 laser will be used for the multi-frequency pulsed-field (up to 70 T) ESR spectroscopy of strongly-correlated magnets, including low-dimensional and frustrated spin systems, high-Tc superconductors and related compounds, multiferroics, etc. Electron spin resonance (ESR) spectroscopy is based on the detection of resonance absorption...
For the clinical industry, the transition from Atomic Absorption Spectroscopy (AAS) to Inductively Coupled Plasma – Mass Spectrometry (ICP-MS) has been gradual over the past two decades.
The ability to measure more elements per sample in less time has made it the technique of choice. With a large dynamic range and ultra-low detection limits, ICP-MS is able to meet the growing demands within the industry. Although, before samples can be analyzed, which can include whole blood, blood serum, blood plasma, urine and other biological material...
Chromatrap® has published a new application note that demonstrates how its unique solid state patented technology provides unrivalled sensitivity allowing users to perform ChIP assays using as few as 1000 cells per immunoprecipitation.
Usually large cell numbers are required for performing ChIP, which poses something of a challenge when dealing with limited starting material. The available techniques for tackling small amounts of sample, rare cell types or difficult cell types which provide low yield of chromatin are usually long and complex, and involve DNA amplification or the spiking of samples with chromatin from another source. In the application note, the authors demonstrate how...
Thermo Fisher Scientific’s Cryo-TEM provides critical information for small molecule and biologic drug discovery
A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery. NovAliX’s new laboratory will use the cryo-TEM to provide two-dimensional...
Research teams based at the Universities of Dundee and Edinburgh are looking to partner with the pharmaceutical industry to better understand the biological processes that could allow the development of new drugs to support tissue regeneration or repair.
The National Phenotypic Screening Centre (NPSC) at the University of Dundee and the Medical Research Council (MRC) Centrefor Regenerative Medicine (CRM) at the University of Edinburgh have signed a Memorandum of Understanding that commits them to work more closely together as they strive to translate novel biological discoveries into new stem...
Genevac has published an informative customer article that reviews the development of a new sample preparation method using its EZ-2 centrifugal evaporator to help simplify and accelerate the detection and quantitation of algal toxins in surface water.
Due to a warming global environment there has been a rise in occurrences of cyanobacteria blooms in lakes which can generate cyanotoxins. With surface water a major source of drinking water, the presence of cyano bacterial blooms pose a potential threat to human health. Using Ultra-high Performance Liquid Chromatography (UPLC) researchers have been able to...
The fluorescent probe NR12S detects changes in plasma membrane cholesterol levels
The cell membrane is a bilayer of phospholipids with embedded proteins. It contains cholesterol that determines the membrane’s fluidity, permeability and activity of membrane proteins. Changes in membrane cholesterol are implicated in diseases such as Alzheimer’s and cancer, demanding its investigation....
Chromatrap® reports on the excellent results achieved by customers using their 96 well high throughput plates for ultra-pure DNA purification.
Using proprietary filtration media that offer much higher loadings of active material, assay times of less than 5 minutes are routinely achievable. Customers report that using Chromatrap® DNA purification kit that DNA samples ranging from 50 bp up to 23 kb can be purified with up to 98% recovery.....
They use a co-located SEM-Raman system from Renishaw to provide comprehensive in situ sample characterisation. Dr Guillaume Wille works in the Mineral Physicochemical and Textural Characterization Unit. In describing the analysis methods used at BRGM, Dr Wille said, “Numerous techniques are used, like infrared spectroscopy, X-ray diffraction, electron microscopy and microanalyses....
Dr Nic Mullin is a senior experimental officer in the SPM Group of Professor Jamie Hobbs in the Department of Physics & Astronomy at the University of Sheffield. His research is based around instrument development for scanning probe microscopy for the study of soft matter and biological systems at the molecular scale....
People with certain forms of early-onset Parkinson’s disease could potentially benefit from taking a medication used to treat certain forms of cancer, according to new research by University of Leicester scientists and funded by the Medical Research Council. The study, which has been published in Science Matters, suggests that folinic acid, which is used in medications to treat bowel cancer, can also protect neurons....
Flow cytometry supervisor Brian Ngo explained: “Our laboratory uses flow cytometry to detect specific biomarkers that help to diagnose leukaemia, and this involves pipetting microliter volumes of antibodies and samples. When you are doing a lot of pipetting, user comfort is very important and so we decided to invest in electronic – rather than manual – pipettes....
Air pollution can change the way bacteria behave and can change their potential to cause disease
The LIMS will be used by the Group’s veterinary laboratory. Agrihealth veterinary laboratory is a busy facility based in County Monaghan, Ireland and specialises in the analysis of various types of agricultural and food samples. Much of the analysis carried out is for salmonella and campylobacter for the poultry industry....
According to a study led by the University of Glasgow, and published today in the American Journal of Clinical Nutrition (AJCN), abnormal sleeping habits increase the risk of obesity for those who are genetically predisposed to being overweight. The findings, based on data from the UK Biobank, emphasise that while genetics have a large role to play in obesity, lifestyle also plays an important role....
Clinical trials are becoming increasingly complex, due in part to an array of circumstances including the use of multiple data capture modalities and the need to evaluate more study endpoints than ever before. Additionally, global trials continue to be managed by a growing number of stakeholders, which heightens risks and uncertainties....
Advanced Chromatography Technologies (ACT) Limited have recently published a new and comprehensive LC Applications Guide which brings together a huge range of latest LC and LC-MS applications from fields including Clinical, Forensic & Bioanalysis, Environmental, Food & Beverage, Pharmaceutical, LC-MS and more....
Recent biomedical research shows that many serious diseases – in particular cancer – are caused by persistent disruptions of cellular communication processes. These processes use a biochemical reaction called phosphorylation to control the information flow. This biochemical computer is faulty in cancer, and drugs that block rogue phosphorylation reactions have proven effective cancer treatments....
Combining user-friendly NanoAssemblr™ microfluidics systems with advanced nanoparticle technology, the company has developed the Neuro9™, Astro9™ and iNeuro9™ non-viral gene transfection kits to allow rapid and easy knockdown or expression of genes in primary cells, both in vitro and in vivo....
BioAscent Discovery and Merz Pharmaceuticals GmbH, part of the Merz Pharma Group, have entered into a Master Service Agreement (MSA), under which BioAscent provides a comprehensive outsourced compound management service for a significant part of Merz Pharmaceutical’s compound collection, in both solid and liquid forms....
Improved treatments for people with severe asthma are a ‘step closer’ after a research team led by the University of Leicester identified a breakthrough in the cause of airway narrowing. Scientists have, for the first time, discovered that an active form of a key protein, HMGB1, is increased and related to narrowing of the airway in people with severe asthma...
The FIRL-100 laser will be used for the multi-frequency pulsed-field (up to 70 T) ESR spectroscopy of strongly-correlated magnets, including low-dimensional and frustrated spin systems, high-Tc superconductors and related compounds, multiferroics, etc. Electron spin resonance (ESR) spectroscopy is based on the detection of resonance absorption...
The ability to measure more elements per sample in less time has made it the technique of choice. With a large dynamic range and ultra-low detection limits, ICP-MS is able to meet the growing demands within the industry. Although, before samples can be analyzed, which can include whole blood, blood serum, blood plasma, urine and other biological material...
Usually large cell numbers are required for performing ChIP, which poses something of a challenge when dealing with limited starting material. The available techniques for tackling small amounts of sample, rare cell types or difficult cell types which provide low yield of chromatin are usually long and complex, and involve DNA amplification or the spiking of samples with chromatin from another source. In the application note, the authors demonstrate how...
A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery. NovAliX’s new laboratory will use the cryo-TEM to provide two-dimensional...
The National Phenotypic Screening Centre (NPSC) at the University of Dundee and the Medical Research Council (MRC) Centrefor Regenerative Medicine (CRM) at the University of Edinburgh have signed a Memorandum of Understanding that commits them to work more closely together as they strive to translate novel biological discoveries into new stem...
Due to a warming global environment there has been a rise in occurrences of cyanobacteria blooms in lakes which can generate cyanotoxins. With surface water a major source of drinking water, the presence of cyano bacterial blooms pose a potential threat to human health. Using Ultra-high Performance Liquid Chromatography (UPLC) researchers have been able to...
The cell membrane is a bilayer of phospholipids with embedded proteins. It contains cholesterol that determines the membrane’s fluidity, permeability and activity of membrane proteins. Changes in membrane cholesterol are implicated in diseases such as Alzheimer’s and cancer, demanding its investigation....
Using proprietary filtration media that offer much higher loadings of active material, assay times of less than 5 minutes are routinely achievable. Customers report that using Chromatrap® DNA purification kit that DNA samples ranging from 50 bp up to 23 kb can be purified with up to 98% recovery.....