Chaperones keep the tumor suppressor protein p53 in check. The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide. New research conducted at Technical University of Munich (TUM) shows that this inborn cancer prevention only works when special proteins, known as chaperones, allow it to take place....
The development of the UK’s first dedicated Vaccines Manufacturing Innovation Centre (VMIC) has moved a step closer with the contract to design an advanced array of laboratory and production facilities within a ‘cleanroom wrap’ environment being awarded to WHP. The multi-disciplinary engineering company has won the design work as part of plans for the specification of versatile new cGMP suites and filling rooms for the VMIC, which is being built...
Merck, a leading science and technology company, announce its participation in a collaboration with the Vaccine Formulation Institute and the European Vaccine Initiative. The effort will provide vaccine process development training courses within TRANSVAC2, a collaborative infrastructure project under Horizon 2020. “Involvement in this project is a natural extension to our longtime focus on accelerating vaccine....
MtoZ Biolabs, an international contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services, developed SILAC-based CoIP-MS service to assist researchers study in protein. Co-Immunoprecipitation (CoIP) is a classical method for studying protein interactions based on the principle that antibodies specifically recognize specific antigens.....
Merck, a leading science and technology company, has announced that it has opened the next round of applications for startup companies to participate in the global Merck Accelerator program. Startups can choose to participate in one of the two programs, either at the company’s Innovation Center at global headquarters in Darmstadt or at its China Innovation Hub in Shanghai.
A2LA is proud to announce the issuance of its first accreditation, and the first such accreditation in the world, to the newly published standardISO 20387:2018 – Biobanking – General requirements for biobanking. ISO 20387 contains requirements designed to demonstrate the competence of a biobank’s operation and ability to provide biological material and associated data for research and development....
Researchers at the University of North Texas are using INTEGRA’s VIAFLO 96 electronic pipette to increase the throughput of their ELISA, Luminex and flow cytometry workflows, as well as to improve the reproducibility of their results. The Applied Physiology Laboratory at UNT focuses on research in two key areas, physiologic and immunologic consequences of weight change, and using nutritional countermeasures to maximize immune health after exercise and performs analysis and testing...
Analytik reports on how the School of Biological & Chemical Sciences at Queen Mary University, London (QMUL) has been using a LM20 Microfluidizer for cell disruption of a broad range of cell types including E. coli, Yeasts and Diatom. The School of Biological and Chemical Sciences at QMUL is one of the UK’s leading life science research departments, with a multi-disciplinary approach to teaching and research....
Cal or automatic calibration is a feature that's found in advanced OHAUS balances such as the Explorer and the Adventurer series. Let's explore what this feature means to you. What does Expansion/Contraction Mean For High Precision Applications? Literally everything that you come in contact with on a daily basis, be it a solid object, a liquid, or the gases around you....
TTP plc (TTP), a leading independent technology and product development company, has announced that it has partnered with Quotient Ltd, a commercial-stage diagnostics company committed to transforming transfusion diagnostics and beyond to develop and implement a state-of-the-art manufacturing facility for Quotient's proprietary MosaiQ system....
Thermally activated delayed fluorescence (TADF), also known as E-type delayed fluorescence, was first observed in 1924 by Francis Perrin.1,2 In 2012 it received a resurgence in attention, and exposure to a wider audience, when Professor Chihaya Adachi and colleagues at Kyushu University used the TADF mechanism to harvest triplet excitons in organic light emitting diodes (OLED) and create a new type....
Vetter, a global operating Contract Development and Manufacturing Organization (CDMO) announced that a significant level of expansion activities are nearing completion at its US clinical manufacturing facility located at the Illinois Science & Technology Park in suburban Chicago. The ongoing growth of the facility will help satisfy existing and ever-increasing future customer requirements...
Uniqsis reports on how its Flow-UV™ inline UV-Visible spectrometer sets a new benchmark for real-time dispersion and nanoparticle distribution and agglomeration experiments. Designed for use with almost any commercially available flow chemistry system, Flow-UV™ allows dispersion experiments to be monitored in real time so that product collection can be controlled...
The search for new drugs to combat diseases more effectively could be revolutionised through a new £30 million electron microscopy project. Experts would be able to see, for the first time, how a particular drug works within a patient at a cellular level or the molecular processes set in motion by a genetic mutation. The technology aims to create 3D images of cells at very high resolution...
In a paper published in the American Chemical Society journal researchers from Bourgogne University showed that the use of superparamagnetic iron oxide nanoparticles (NPs) using multi modal – PET/MRI - showed promising improvements in imaging capabilities. Using an MR Solutions, cryogen free, 3T scanner with a PET clip on the sequential images were found to be highly beneficial...
Kanazawa University researchers use high-speed microscopy to investigate native structure and conformational dynamics of hemagglutinin in influenza A. The influenza A viruses, which have instigated deadly pandemics in the past, still remain a major global public health problem until today. Molecules known as virulence factors are produced by bacteria, viruses, and fungi to help them to infect host cells....
Sygnature Discovery has today announced a collaboration with SilcsBio, a scientific software company focused on high-throughput fully atomistic simulations of protein targets and protein-ligand structures. SilcsBio has provided Sygnature with access to its SILCS (Site Identification by Ligand Competitive Saturation) and SSFEP (Single Step Free Energy Perturbation) software.
BioCity, a pioneering life science incubator and business collective, today announced investment in Deep Branch Biotechnology, a Nottingham-based carbon recycling start-up, developing technology that transforms polluters into producers. Unlike traditional carbon storage technology that simply collects and stores carbon dioxide, Deep Branch’s carbon recycling solution converts carbon dioxide....
Discovery Park, a thriving high-quality science park playing a key role in the South East of England’s life sciences community,and MedCity, which supports and grows the world-leading life sciences ecosystem of the Greater South East of England, are pleased to announce that they are partnering on the high-profile Angels in Med City programme....
A major milestone on its strategic mission to lead in sepsis diagnostics, Beckman Coulter has announced that its Early Sepsis Indicator has received 510(k) clearance from the U.S. Food and Drug Administration. Sepsis is a global healthcare crisis that affects more than 30 million people worldwide.1 The Early Sepsis Indicator is a first-of-its-kind, hematology-based cellular...
Research has revealed that a new blood test is able to detect disease relapse up to two years earlier than imaging in patients with early-stage breast cancer. The research, carried out by the University of Leicester and Imperial College London and funded by Cancer Research UK, showed that the blood test was able to detect 89 per cent of all relapses, on average 8.9 months quicker than imaging...
Integrated DNA Technologies (IDT) is once again proudly partnering with the International Genetically Engineered Machine (iGEM) Foundation to support young researchers and promote scientific progress. IDT is sponsoring theiGEM competition 2019 as a platinum sponsor for the sixth consecutive year. In order to make DNA synthesis accessible to all, the company will...