European wheat harvests could be increased by more than 5 tonnes a hectare according to newly published research into the crop’s untapped genetic potential. The first of its kind study from agricultural institute Rothamsted Research shows that in some European countries the grain yield could be increased by up to 90% when compared to typical harvests from today’s commonly used varieties. Yields in the UK could be increased by half as much again....

Collaboration to initially focus on the development and global commercialisation of a suite of CelLuminate dyes, specifically created to revolutionise live cell imaging by enabling cells to remain functional and viable for up to 14 days. Abcam plc, a global innovator in life science reagents and tools, and SomaServe Ltd, a Pharma service and specialist reagent business exploiting PolyNaut® Technology, have announced a partnership to commercialise the cell delivery potential of...

Antibiotic-resistant bacteria are increasingly the source of deadly infections. A team of scientists from the Technical University of Munich (TUM) and the Helmholtz Center for Infection Research (HZI) in Braunschweig have now modified an approved cancer drug to develop an active agent against multidrug-resistant pathogens. The methicillin-resistant Staphylococcus aureus (MRSA) is the source of severe and persistent infections....

Merck, a leading science and technology company, has announced that it has signed a license agreement providing Promega Corp., a global life science manufacturer based in Madison, Wisconsin, USA access to Merck’s foundational CRISPR intellectual property. Promega will use Merck’s CRISPR genome-editing technology to create research products and services, including those for drug development.

Sartorius, a leading international partner of life science research and the biopharmaceutical industry, and the German Research Center for Artificial Intelligence (DFKI) have established the Sartorius AI Lab (SAIL) research laboratory. On the DFKI campus in Kaiserslautern, the use of artificial intelligence (AI) in Sartorius products and platform solutions is being experimentally tested and further developed at SAIL....

BioAscent scientists, working in collaboration with teams at the German Cancer Research Center and the Pivot Park Screening Centre as part of the European Lead Factory project, have helped to discover potent and selective inhibitors of enzymes associated with the development of some cancers and neurodegenerative diseases. The findings, published in ChemMedChem, represent an initial step in the development of potential new cancer treatments....

Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), kicks off the 2020 LIMS Webcast Series on Wednesday, January 15th with Lab Automation Today: Five Key Trends Currently Impacting Your Laboratory. This webcast will focus on five trends challenging many analytical testing laboratories today and the role that a LIMS can play in addressing the impact of these trends....

To enable researchers from European institutes to extend innovative structural biology research, the EU has invested 10 million euro to iNEXT-Discovery, through its Horizon 2020 program. The iNEXT-Discovery consortium, coordinated by Prof. Dr. Anastassis Perrakis from the Netherlands Cancer Institute and Oncode Institute, aims to facilitate the generation of knowledge for the development of new drugs, advanced vaccines, novel biomaterials, engineered enzymes for food production, efficient biofuels, and other benefits....

Until January 15, 2020, researchers up to 35 years, with an advanced degree, who are working in Europe are invited to apply online for the Eppendorf Award for Young European Investigators 2020. This prize acknowledges outstanding contributions to biomedical research in Europe based on methods of molecular biology, including novel analytical concepts. It has been awarded, in partnership with Nature, since 1995....

Breast cancer is one of the most common forms of cancer facing women worldwide. To help fight this disease, INTEGRA launched PIPETGIRL – a limited edition of the PIPETBOY acu 2 pipette controller – in 2015 to support internationally renowned research institutes dedicated to finding a cure for breast cancer, donating 10€ / US$15 from each sale....

Climate crisis, artificial intelligence, and vaccines top the list of 2019’s most discussed research. From the increasing use of artificial intelligence to the climate emergency facing us all, many of this year’s most polarizing issues feature in the Altmetric Top 100. The annual Altmetric Top 100 highlights research published in 2019 that has generated significant international online attention and discussion...

2019 was an exciting year for science as it marked the 150th birthday of the periodic table of elements and as a result, the year was designated as the International Year of the Periodic Table. From an old invention to modern day discoveries, in this article Radleys take a look at some more recent advances in the field of Chemistry and the highlights of 2019....

PhoreMost has leveraged its proprietary SITESEEKER® drug discovery platform and PROTEINi® libraries to identify a peptide sequence inhibiting a novel protein target which was previously thought to be undruggable, relevant to an oncogenic cellular pathway. Cresset Discovery Services has been contracted under a flexible service agreement to determine how the peptide binds to the target, and to ultimately help find small molecules that have the same effect....

BioMed X has announced the successful completion of their first research collaboration project with AbbVie in the field of tau-mediated neurodegeneration in Alzheimer’s disease. BioMed X received a milestone payment and the results of the project were transferred to AbbVie. The BioMed X team successfully developed research tools to assess disease-associated post-translational modification signatures of the tau protein in the brains and cerebrospinal fluids...

Scientists have tested a new way to protect crops from a widespread and devastating bacterial disease, without using environmentally damaging chemical sprays. An interdisciplinary team at the University of Glasgow have revealed a new method that could protect many important crop species against the common crop bacteria Pseudomonas syringae (Ps). Ps and related bacterial species attack a wide variety of important crops in the UK and worldwide...

Testa Analytical Solutions reports on considerable interest from protein scientists to use Dynamic Light Scattering (DLS) as a tool for screening for the presence of aggregates as it is extremely sensitive to these larger compounds. Applications Lab Manager - Raffaele Carano said "Protein aggregation is a common challenge in the manufacturing of biological products. Protein scientists particularly like DLS because it provides them with a simple, fast and non-destructive test for aggregate detection....

We live in a three-dimensional ever-changing world. Yet in microscopy, our ability to image in 3D and at the speeds required to observe fast living processes remains a challenge. Compared to other light microscopy techniques, fluorescence microscopy can achieve high specificity and contrast, though there are still major limitations in signal-to-noise ratio and phototoxicity.

Deben, a leading provider of in-situ testing stages together with innovative accessories and components for microscopy, reports on the University of Surrey’s efforts to develop the groundwork of new, state of the art ceramic composites that will revolutionise the treatment of oral disease. Dr Tan Sui is a Materials Engineering Lecturer (Assistant Professor) in the Department of Mechanical Engineering Sciences at the University of Surrey, UK...

Intellegens, an artificial intelligence (AI) start-up, and, Optibrium™, leading providers of software and services for drug discovery, have announced joint success in the Open Source Malaria (OSM) global initiative aimed at identifying the best predictive models for antimalarial compounds. Together, the companies developed one of the top models, deploying a cutting-edge deep neural network algorithm [1], Alchemite™, to accurately predict active compounds...