INTEGRA Biosciences offers liquid handling solutions and magnetic modules to streamline every stage of NGS sample preparation. These innovative tools help to reduce errors, improve the precision and reliability of sequencing data, and provide more efficient processes. NGS is a high throughput technology that rapidly sequences large volumes of DNA or RNA, enabling comprehensive analysis of genetic material for applications like genomics, transcriptomics and personalized medicine...

Aston Institute for Membrane Excellence (AIME) has received a £500,000 grant from the Wolfson Foundation to purchase an ultrafast confocal spinning disc microscope. This instrument will accelerate AIME research, led by Professor Roslyn Bill, into treatments for dementia and other forms of cognitive decline. An ultrafast spinning disc confocal microscope enables faster, higher-resolution images of biological processes than is currently possible at AIME...

Engineers from The University of Warwick’s Integrative Synthetic Biology Centre and Imperial College London’s Department of Bioengineering have unveiled how to engineer microbial ‘cell-factories’ to boost the manufacture of high-value chemicals that are used in everyday products like domestic goods, clothes and food. To date cell-based systems have been less efficient than existing petrochemical processes due to natural constraints within living cells...

Did you know some viruses don’t cause illness and can instead be used to treat disease? Biotechnology startup Axonis Therapeutics reprogrammed a virus to carry a novel gene therapy to neurons to treat neurological conditions like Alzheimer’s, Parkinson’s, and spinal cord injury. The company needed a way to test the therapeutic in a mature human brain model, which is difficult to produce on Earth...

Leading science and innovation campus, Discovery Park, in Sandwich, Kent has launched applications for the fourth cohort of its immersive business growth competition, ‘Discovery Spark’. Supported by Capital Enterprise Network and Cancer Research UK (CRUK), Discovery Park’s latest Discovery Spark programme will have an oncology theme. It invites cancer tech start-ups looking to accelerate their business to apply...

In materials science, achieving precise and repeatable scanning electron microscopy (SEM) analysis requires pristine sample surfaces. However, handling and preparation methods frequently degrade the sample’s condition, making it challenging to observe the material's essential features. Here, Britta Siefer, SEM expert at Thermo Fisher Scientific, explains how a reliable workflow can preserve sample integrity for quality analysis...

Pioneering use of artificial intelligence (AI) could cut the time it takes to bring life-saving treatments to patients. This represents just one example of innovation being championed by the UK's seven new regulatory science powerhouses. Innovate UK – the UK’s innovation agency, in partnership with the Medicines and Healthcare products Regulatory Agency (MHRA), Office for Life Sciences, and the Medical Research Council have announced seven Centres of Excellence for Regulatory Science and Innovation...

Illumina, Inc., a global leader in DNA sequencing and array-based technologies, has announced a pilot proteomics program to analyze 50,000 UK Biobank samples in collaboration with deCODE Genetics, Standard BioTools, Tecan, GSK, Johnson & Johnson, and Novartis. The pilot program is based on Illumina's upcoming proteomics assay, Illumina Protein Prep™, powered by SOMAmer® technology, a next-generation sequencing (NGS) based solution that will help scale access to proteomic insights...

The Roslin Institute, located on the Easter Bush Campus at the University of Edinburgh’s College of Medicine and Veterinary Medicine, is a thriving hub of innovation in the field of animal biosciences. Research groups hosted by the institute carry out various cutting-edge projects and frequently rely on biological samples, which must be stored at low or ultra-low temperatures (ULT) around the clock to preserve their viability. This article discusses key considerations when choosing cold chain storage solutions for any lab...

AMSBIO has implemented a program of investment to support the students at Penn State Lehigh Valley, part of Pennsylvania State University, in their transformative Course-based Undergraduate Research Experience (CURE) program. The CURE program, led by Dr. Jacqueline McLaughlin, allows students to dive into real-world research projects that tackle critical challenges in health and medicine...

Thermo Fisher Scientific Inc., the world leader in serving science, has announced the UK Biobank Pharma Proteomics Project (UKB-PPP) has selected its Olink® Explore Platform to support the world’s largest human proteomics study of its kind. UKB-PPP aims to analyze more than 5,400 proteins from 600,000 samples to fuel the discovery of new protein biomarkers that can be used to predict, diagnose and treat diseases...

Maximise efficiency and precision in the analysis of monoclonal antibodies (mAbs) and antibody-drug-conjugates (ADCs) with YMC's tailored solutions. This collection of applications combines proven reliability with cutting-edge technologies to optimise your workflows and save valuable lab time. From intact to fragmented mAbs, DAR determination, or native LC-MS techniques, YMC columns provide highly sensitive and reliable methods using ion exchange (IEX), size exclusion (SEC), hydrophobic interaction (HIC), and reversed-phase liquid chromatography (RP)...

Physicists are getting closer to controlling single-molecule chemical reactions – could this shape the future of pharmaceutical research? A new study, published in the prestigious journal Nature Communications, set out to demonstrate for the first time that competing chemical reaction outcomes can be influenced by using the atomic resolution of a scanning tunnelling microscope (STM).

In a new study, published in the journal Nature, researchers from EMBL Barcelona, the University of Texas, the University of Copenhagen, and The Scripps Research Institute have discovered human antibodies that can recognise and target some of the proteins that cause severe malaria. This breakthrough could pave the way for future vaccines or anti-malaria treatments...

AN influential cross-party Lords Committee has written to the Government to raise concerns about its preparedness for future pandemics, describing the current situation as “troubling”. In a letter to Pat McFadden, Chancellor of the Duchy of Lancaster, Baroness Brown of Cambridge, chair of the House of Lords Science and Technology Committee, said experts had raised “troubling concerns about (the UK’s) capacity to manufacture vaccines for future biological threats”...

Choosing a film for a movie night is always a battle. Now imagine if you could pick one that provided a window into some of the most fundamental biological processes that keep us alive. For the first time ever, researchers have captured a real-time molecular movie to show how two essential cellular processes – transcription and translation – interact with each other in bacteria...

Researchers have developed a new multiple organ-on-chip system to help study how neurotoxins move from the gut to the brain. The model system simulated how a neurotoxin in the gut can trigger the brain cell death seen in Parkinson’s disease, in a proof-of-concept study from the Quadram Institute, University of Hull, University of Essex and at the UK Health Security Agency (UKHSA).

Titian Software (“Titian”), a market leader in life sciences sample management software, has announced that Griffith University’s Compounds Australia, Australia’s only dedicated compound management facility, has selected Titian’s Mosaic Sample Management platform (“Mosaic”) to manage their extensive compound collection and support future growth. Mosaic will enable optimisation of workflow efficiencies at Compounds Australia, underpinning the facility’s strategic growth to meet the needs of a growing drug discovery sector. ..

Clinisys WinPath go-lives at Northern Health and Social Care Trust and the cervical cytology screening service complete phase three of the CoreLIMS programme to transform pathology services across the country. The transformation of pathology services across Northern Ireland has achieved another milestone, with the completion of phase three of the CoreLIMS programme to deploy Clinisys WinPath to all five health and social care trusts and the blood transfusion service...