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mRNA Profiles as Close to Biological Reality as Possible

publication date: Jul 30, 2019
 | 
author/source: MicroGEM

mRNA-Profiles-as-Close-to-Biological-Reality-as-Possible


Extraction of RNA is well-known to be a difficult process due to the low stability of the RNA molecules and the abundance of RNases.

MicroGEM’s RNAGEM solves this with extremely fast, temperature-driven RNA extractions that simultaneously lyse cells and strip protein complexes from nucleic acids, thereby allowing higher processivity of polymerases. The result is greater sensitivity - especially with low abundance transcripts. Reduced handling and efficient template preparation mean that RNAGEM generates mRNA profiles as close to the biological reality of the sample as possible.

mRNA-Profiles-as-Close-to-Biological-Reality-as-Possible

The simple, single-tube workflow results in high, linear yields over a wide range of sample sizes in less than 10 minutes (less than 20 minutes with DNA removal).

RNAGEM is a powerful, broad-specificity, thermophilic proteinase that aggressively destroys ribonucleases. It is ideal for preparing RNA from mammalian cell culture, laser capture micro-dissections and FACS-prepared cell populations.

Download the application notes to learn about RNAGEM’s extremely efficient ability to extract RNA from a single cell to 100,000 cells. Find out how RNAGEM’s excellent linearity provides a superior approach to estimating total RNA quantity for sample normalization.

 

view | download APP Notes

 


On-Demand Webinar

Watch this on-demand webinar demonstrating how you can simplify your extraction workflow and move quickly to your downstream application, analysis, and results.

 

mRNA-Profiles-as-Close-to-Biological-Reality-as-Possible

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