An Automated Gating Workflow Can Shorten Hands-On Time by up to 75%

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, introduces an automated solution for the grueling and time-consuming process of manual gating flow cytometry data, with no programming skills required. This revolutionary feature is part of the new Cytobank v10 platform upgrade which is available now.

Inconsistencies among operators have been identified as one of the top contributors to variability in flow cytometry data analysis. Cytobank Automatic gating can address this issue and reduce variability compared to manual gating. Also, depending on the complexity of the gating strategy, Cytobank Automatic gating can take up to 75% less time to complete compared to manual gating of the full dataset for population identification.

“When customers talk we listen, and we’ve heard a lot about the reproducibility crisis in biomedical research, along with the struggles that come with inconsistencies from manual gating,” said Nicole Weit, Senior Technical Product Manager for Biodiscovery Flow Software. “Manually gating files is tedious and time consuming, especially for large and complex panels or datasets with many files. Laboratory staff can end up adjusting gates for hours or sometimes even days. We’ve been on a relentless mission to stop the madness and provide a solution to these challenges, so that customers can level up their flow cytometry data analysis without having to be programmers.”

Cytobank Automatic gating allows lab staff to set up their own gating strategy on a set of files, train a model and then reproducibly analyze more samples using the trained model. The trained model can then easily be shared with colleagues around the globe. This two-step workflow saves users hands-on time, reduces variability, and empowers collaboration across institutions. When new data needs to be analyzed, users simply start a new automatic gating inference run with the trained model.

The Cytobank platform is a cloud-based analysis solution for cytometry data and provides powerful visual data management and controlled data sharing. By providing access to machine learning-assisted analysis without the need for coding knowledge or programming skills, the Cytobank platform helps researchers discover new insights from high-dimensional data with the use of unbiased approaches that reduce reproducibility issues, eliminating operator-dependent bias.

A favorite among lab staff, 86% of users* are likely to recommend the Cytobank platform to others and praise the ability to provide illustrations that relate to raw data, effortless data management, and ease in sharing and collaborating with colleagues. Beckman Coulter Life Sciences is uniquely able to support labs from sample to answer when using DURAClone dried reagent technology with the CytoFLEX analyzer family and the Cytobank data analysis platform.

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About Beckman Coulter Life Sciences

Life sciences. Research. Precision manufacturing. If your life’s calling is in any of these or related fields, you need to know Beckman Coulter Life Sciences. Our mission is to empower those seeking answers to life’s important scientific and healthcare questions. Since 1935, the Beckman name has been synonymous with technologies that simplify and automate complex biomedical testing. Decades later, our global organization also came to embody the scientific legacy of the Coulter name. Today, Beckman Coulter Life Sciences is a trusted, worldwide resource for tools to help optimize research and manufacturing efficiency. Centrifuges. Particle counters/analyzers. Automated liquid handlers. Flow cytometers. Genomic reagents. All these products—and many more—continue to make a difference in people’s lives by improving the productivity of dedicated scientists, quality control experts and others. Wherever people need answers, from prestigious universities and major pharmaceutical companies, to small biotech startups, food/beverage and electronics manufacturing facilities, you can find Beckman Coulter Life Sciences.

* Respondents surveyed through TechValidate. For research use only. Not for use in diagnostic procedures.

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