Purolite™ AP+50 resin enables improved cost efficiencies in antibody manufacturing

Ecolab Life Sciences has launched an innovative new resin to help achieve cost savings and optimize operations throughout the antibody manufacturing process. Purolite™ AP+50 is an affinity chromatography resin with a 50-micron bead size offering the highest dynamic binding capacity of the AP resin platform while providing excellent durability for monoclonal antibody capture. It also leverages Ecolab’s patented Jetted resin bead manufacturing technology, an innovative approach that enables lot-to-lot consistency and shorter lead times. It is the latest addition to Ecolab’s robust Purolite Resin affinity toolbox which helps biopharmaceutical companies and Contract Development and Manufacturing Organizations solve complex purification challenges.

“The ability to effectively improve process economics while maintaining purity is the gold standard of resin purification. As pharmaceutical and biotech companies seek to increase savings and improve business continuity, they are requiring innovative solutions to accelerate and de-risk manufacturing,” said Meeta Gulyani, senior vice president and general manager, Ecolab Bioprocessing. “Our resins are designed to help customers improve their product development platforms and implement next-generation manufacturing processes as well as enhance dual sourcing strategies that can reduce costs and bolster supply chains.”
Purolite AP+50 resin joins Ecolab’s full suite of purification resins including the recently launched Purolite DurA Cycle™ A50 for longer lifetimes and Purolite 70 CH1 which targets complex antibody fragments. Together, they support process intensification strategies and cost of goods reduction, which are critical in late-phase, large-scale manufacturing.

The announcement of Ecolab’s latest resin follows news of the opening of its newest Bioprocessing Applications Lab in King of Prussia, Pennsylvania. The new lab complements its UK-based facility, providing dual continent technical support capabilities, including resin screening and development applications to address growing customer demand around the world.

About Ecolab

A trusted partner for millions of customers, Ecolab (NYSE:ECL) is a global sustainability leader offering water, hygiene and infection prevention solutions and services that protect people and the resources vital to life. Building on more than a century of innovation, Ecolab has annual sales of $16 billion, employs approximately 48,000 associates and operates in more than 170 countries around the world. The company delivers comprehensive science-based solutions, data-driven insights and world-class service to advance food safety, maintain clean and safe environments, and optimize water and energy use. Ecolab’s innovative solutions improve operational efficiencies and sustainability for customers in the food, healthcare, high tech, life sciences, hospitality and industrial markets.