Follow us...

 

Search News Archives

Monthly Newsletter

 

Lab Bulletin May Newsletter

view the latest issue

Subscribe

News Channels

 

New Laboratory Products

 

Lab News

 

Microscopy & Image Analysis

 

Separation Science

 

Research & Case Studies

 

Literature

 

Videos

 

Events | Webinars

 

 

 

Conferences | Events

Sartorius Stedim Biotech presents Sartocon Slice 50 ECO

publication date: Oct 5, 2016
 | 
author/source: Sartorius Group

New small-scale crossflow device for low-viscosity water-based protein solutions

Sartocon® Slice 50 ECOSartorius Stedim Biotech (SSB), a leading international supplier for the biopharmaceutical industry, has extended its product line of small-scale Sartocon® Slice 50 crossflow devices by Slice 50 ECO. This new crossflow filter has been specially designed for water-based protein solutions with viscosities below 3 cp. The crossflow cassette can typically be used in biotech applications, such as filtration of IgG, blood factors and peptides, especially involving membrane screening and small-volume process development. The reduced flow channel geometry of Sartocon® Slice 50 ECO lowers the recirculation pump requirements by as much as 50% versus a standard design. Only half of the pump energy is needed, considerably decreasing the sheer stress on all protein solutions.

Like the standard Slice 50 cassette, Sartocon® Slice 50 ECO is offered as an encapsulated and ready-to-use crossflow module. Offered in a wide selection of molecular weight cutoffs, it has a filter area of 50 cm2. The cGMP-validated self-contained filtration unit eliminates the need for a compression holder and is available in a choice of two polymers:

The first polymer, a stable polyethersulfone membrane (PESU) that is well established in the biopharmaceutical industry is ideal for a broad pH and temperature range. The second polymer, the Hydrosart® membrane, is a stable, cross-linked regenerated “cellulosic” polymer. It is also suitable for a broad pH range and can be cleaned and depyrogenated using up to 1 N NaOH at elevated temperatures. This membrane is extremely hydrophilic, making it non- protein-binding and virtually non-fouling. It is very easy to clean and delivers an exceptionally high product flux and product yield.

“With our new product, we are offering the industry a high-performance device for especially efficient filtration of low-volume aqueous protein solutions. Due to its features, such as low feed flow and low adsorption, Sartocon 50 ECO is a very cost-effective solution,” stated Frank Meyeroltmanns, expert for crossflow filtration at Sartorius Stedim Biotech.

Major benefits of the Sartocon® Slice 50 cassette are its scalability and identical materials of construction. These properties ease transfer of process development results to the next scale- up level. In addition, the new filter device can be readily interfaced with SSB’s benchtop crossflow system SARTOFLOW® Smart and with many other laboratory-scale filtration systems. 


more about sartorius
more news from sartorius

 


If you have not logged into the website then please enter your details below.



 

 

Popular this Month...

Our Top 10 most popular articles this month

 

Today's Picks...

 

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd

 


Promotions

 

Media Partners