Search News Archives
Follow us on
Conferences | Events

Media Partners

 

New Poster on the ambr 15 fermentation Micro Scale Bioreactor System

publication date: Jun 9, 2016
 | 
author/source: Sartorius Group

ambr 15 f with operator

Presents data showing how the system can be used to support batch and high density fed batch microbial screening

Sartorius Stedim Biotech (SSB) today announced a poster presented at BPI Europe, entitled, ‘A novel automated micro bioreactor for high density fed batch microbial screening applications’ is now available online. The poster details how scientists at SSB assessed the new ambr® 15 fermentation system as a model for benchtop bioreactors to support development of batch and high density fed-batch microbial cultures.

The poster presents oxygen transfer rates, dissolved oxygen (DO) and pH control data from E.coli batch cultured in the ambr15 fermentation system, which consists of 24 single-use, stirred micro bioreactors integrated to an automated workstation. These results show that the pH and gas flow in the ambr15 fermentation micro bioreactors (8-12mL working volume) are tightly controlled and can achieve a KLa of approximately 380 h-1, which is comparable to the oxygen transfer rate generated in a production scale bioreactor.

The poster also details scale-up data from E. coli cultured in a fed-batch process in ambr15 fermentation micro bioreactors, a 1L Dasgip benchtop bioreactor and an SSB ambr 250 (250 mL) mini bioreactor. The results demonstrate that the growth profiles from all three bioreactor types have good comparability and high density cultures with an OD600 > 150 can be achieved in the ambr15 fermentation micro bioreactor.

Dr. Barney Zoro, ambr15 fermentation Product Manager, at SSB commented: “An automated micro bioreactor system needs to have a combination of tightly controlled pH and DO, semi-continuous feed supply and the right type of culture agitation to provide consistent, reproducible and predictive results.”

Zoro adds: “The data in our poster indicates that the ambr15 fermentation system easily achieves these parameters, showing scientists how they could replace their shake flasks and bench top bioreactors with a micro bioreactor to significantly increase throughput of their microbial strain selection studies.”


more about sartorius


more news from sartorius


 


If you have not logged into the website then please enter your details below.



 


Popular this Month

 

Win a PIPETBOY from the new Integra summer collection!

 

Great Savings off Selected GC Columns

 

CytoSMART raises 5.2 million Euros for further product innovation and growth

 

High Volume Sample Storage in Space Efficient 96-Well Format

 

Cherwell Publishes Guide on Sterility Testing

 

Effective Removal of DMSO from Stored Samples

 

ATL Webcast: A Practical Guide to Selecting the Right LIMS

 

Genetic study reveals how gut bacteria work to keep us healthy

 

Lonza Establishes Custom Cell Biology Services to Offer Unique Manufacturing and Testing Capabilities

 

Thermo Fisher Scientific Opens Food Safety Customer Solution Center in India

 

 


 

 


 

Can't find what you are looking for?

Search by company or by product


Company Name:

Product:


 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd