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New Flash Cartridges for Peptide Purification from Biotage
Biotage (STO: BIOT), a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, is pleased to announce the launch of Biotage® SNAP Bio C18 and Biotage® SNAP Bio C4 cartridges - a new range of high performance flash cartridges with wide pore media (300 Å) for reversed phase purification of peptides and other larger molecules.
The purification step (RP-HPLC) is one of the main bottlenecks in the peptide synthesis workflow, limited by small loading amounts, long separation times, poor recoveries and high costs. Biotage® SNAP Bio cartridges offer similar performance, in a flash format, at a fraction of the cost. They have an increased loading capability compared to prep RP-HPLC, enabling more peptide to be processed in a single injection and hence faster, more efficient peptide purification. Flash purification also facilitates a reduction in solvent usage and therefore waste compared to RP-HPLC.
Biotage® SNAP Bio columns are available in 10 g, 25 g, 50 g and 100 g sized cartridges and contain either Biotage® HP-Biosphere C18 or Biotage® HP-Biosphere C4 silica. Developed with a small particle size (20 µm) and large pore size (300 Å) they provide increased resolution and the effective separation of complex peptide mixtures; making flash chromatography an efficient technique for peptide purification.
“Biotage have an excellent record as flash purification innovators. We are in a unique position by being the only manufacturer that can now offer the complete peptide synthesis workflow, from synthesis of crude peptides through to the final purified product.” said Dr. Amit Mehrotra, Global Product Manager, Biotage.