Greiner Bio-One, a technology partner for the diagnostic and pharmaceutical industry, has developed 96 well microplates with a 3D epoxy surface in collaboration with its longstanding cooperation partner PolyAn. The 3D epoxy surface is the ideal platform for covalent binding of proteins, peptides, DNA and oligonucleotides.

The three-dimensional functional matrix allows the development of covalent binding of nucleophiles to the plate surface without complex coupling chemistry. The structure of the matrix, which has a thickness of up to 50 nm, also reduces unspecific binding to a minimum. 

The three-dimensional epoxy 96 well microplates are used mainly if adsorptive binding of peptides or oligonucleotides, for example, to high/medium binding surfaces is ineffective or the binding strength is not sufficient. Areas of application include detection methods such as ELISA, ELI-Spot, protein and peptide arrays and DNA binding.

The 3D epoxy surface is chemically and mechanically highly robust and features particularly homogeneous surface functionalisation. The microplates with a 3D epoxy surface are free of detectable DNases and RNases. The shelf life at room temperature is two years.

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About Greiner Bio-One GmbH - BioScience Division

Greiner Bio-One is specialised in the development, production and distribution of plastic laboratory products. The company is a technology partner for universities, research institutes and the diagnostic, pharmaceutical and biotechnology industries as well. With the BioScience division, Greiner Bio-One ranks among the leading providers of specialised products for the cultivation and analysis of cell and tissue cultures, as well as microplates for high-throughput screening, allowing industry and research most rapid and efficient drug screening. Additionally Greiner Bio-One develops innovative biochip technologies for genotyping.

Under the management of Georg Heftberger, Rainer Perneker and Heinz Schmid, the German headquarters of the BioScience division in Frickenhausen (Baden-Württemberg) controls the whole research and development activities in the product ranges Cell Culture, High-Throughput Screening, Biochips and OEM.

Greiner Bio-One GmbH is a division of Greiner Bio-One International AG, based in Kremsmuenster (Austria). Today Greiner Bio-One International AG generates a turnover of 364 million euros. It has over 1,700 employees and operates globally with 24 subsidiaries and numerous distributors in more than 100 countries.

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About PolyAn GmbH

PolyAn is a nanotechnology company that specialises in modification of surfaces using molecular surface engineering (MSE). PolyAn has been developing and producing consumables for applications where molecular surface engineering is used to prevent unspecific interactions at the surface and raise sensitivity since 1996. The product portfolio includes monodisperse microparticles and carrier materials for microarrays used in molecular diagnostics and life science research. PolyAn also offers customer-specific surface modification of carrier materials and consumables for OEM applications.

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