Follow us...


Search News Archives





View Channel

Laboratory Products



View Channel

Special Offers and Promotions


Microscopy | Image Analysis



View Channel

Separation Science



View Channel

Coronavirus (COVID-19)



View Channel

Research & Case Studies



View Channel

Brochures & Literature



View Channel


Conferences | Events

New ISOLUTE FILTER+ Plates Prevents UPLC Clogging

publication date: May 30, 2017
author/source: Biotage


Biotage has released ISOLUTE® FILTER+, a high performance filtration plate for sample preparation which effectively removes particulates from biological samples, thereby eliminating expensive downtime of UPLC-MS/MS systems.

ISOLUTE® FILTER+ plates provide effective, workflow friendly filtration of diverse biological samples, and are ideal for use with urine prepared by ‘dilute and shoot’ prior to UPLC-MS/MS analysis. Increased back pressures due to particulate accumulation leads to frequent downtime of UPLC systems for replacement or regeneration of the expensive analytical column. ISOLUTE FILTER+ plates are designed to prevent sample particulates from reaching the analytical UPLC column, protecting the analytical system from particulate build up over time.

ISOLUTE® FILTER+ contain a wettable 0.2 μm membrane filter for high performance particulate removal, topped by a depth filter to prevent blocking of the membrane, and can be processed using manual or automated positive pressure or vacuum manifold systems. The filtered samples will be both particulate free and visually clearer, and can be injected directly into UPLC-MS/MS systems.



Sample of whole blood following zinc sulfate precipitation and centrifugation. Left vial unfiltered; right vial filtered using ISOLUTE® FILTER+ plate.

Versatile filtration for multiple sample matrices, including

  • Urine samples
  • Tissue homogenates
  • Pre-precipitated blood samples


Find out more



Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin


Request your free copies HERE




Popular this Month...

Our Top 10 most popular articles this month


Today's Picks...




Looking for a Supplier?

Search by company or by product


Company Name:






Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


Media Partners