instrAction GmbH, Ludwigshafen, the specialist for design and production of selective separation matrices and Protagen AG, Dortmund, a GMP certified service laboratory for protein analysis signed a strategic alliance for the development of customized instrAction ^® Phases for downstream processing of biotherapeutics.

"The instrAction^® Phases are proprietary synthetic chromatography phases which show excellent performance compared to commonly used matrices for e.g. antibody purification. The unique know-how and expertise of Protagen in GMP-compliant protein analysis and related services will be decisive for the development of a portfolio of new tailor made separation phases for the production of recombinant protein drugs, other biotherapeutics and biosimilars", comments Dr. Thomas Schwarz, CEO of instrAction.

"In order to exploit the full value of this exciting new protein purification technology and to convince customers from pharma process development and production, it is important to provide convincing data sets from feasibility studies. Protagen has all the tools and know-how to support instrAction on its way to become the leading company in protein separation technology", underscores Dr. Stefan Müllner, CEO of Protagen.

About Protagen AG - www.protagen.de
Protagen AG is an international leading specialist in the fields of in-vitro diagnostics and GMP-compliant protein analysis. The innovations of Protagen are UNIarray^®, a technology platform for the development of novel serum based diagnostics, as well as UNIchip^®, a versatile product family of protein microarrays for faster development of antibodies.

About instrAction GmbH - www.instraction.com  
instrAction, founded in 1997 and located at the BASF site in Ludwigshafen, develops and manufactures "instrAction^® phases" as novel highly selective resins for chromatography. The proprietary technology enables the immobilization of a wide variety of functional ligands on a polymer network, coated on very different porous backbone materials. Small molecules as well as substances with high molecular weight are separated by highly selective reversible interactions. The high selectivity of an instrAction stationary phase is thereby reached by multivalent-multimodal interactions between target molecule and the functional ligands of the phase, similar to the lock-and-key principle.