Chromatrap®, a business unit of Porvair Sciences, has produced a new 10-page brochure that provides an informative introduction to chromatin immunoprecipitation (ChIP) technology and a detailed comparison of traditional bead based and Chromatrap® solid state ChIP technologies.
Chromatrap® ChIP kits use revolutionary spin columns or microplates which contain discs of an inert, porous polymer to which protein A or G has been covalently attached. This patented format is unique. During an assay, the chromatin/antibody complex is selectively retained by the disc. Flushing with three buffers and an elution step are all that is required to obtain the selectively enriched DNA, making Chromatrap® more efficient in the laboratory. With a fast processing time of...
A new brochure from Copley Scientific offers comprehensive, authoritative guidance to support the development of optimal testing strategies for new and generic orally inhaled and nasal drug products (OINDPs).
‘Quality Solutions for Inhaler Testing, 2015 Edition’ includes detailed information on regulatory requirements and highlights pertinent new additions to the company’s extensive inhaled product testing range. It can be downloaded freely from the Copley Scientific website (www.copleyscientific.com) with print versions available on request from sales@copleyscientific.co.uk. “We know that our customers value help with understanding the testing requirements for OINDPs, which...
Kimberly-Clark Professional publishes mini-guides to aid employee engagement
Leading provider of hygiene, safety and productivity solutions, the KIMBERLY-CLARK PROFESSIONAL* Scientific business has published the second in an ongoing series of health and safety focused mini-guides. Offering bite-sized learning on health, safety and personal protection in the laboratory, these mini-guides are designed to present complex information in a more handy, easy-to-absorb and engaging format. To download free copies...
Prior Scientific has published a new 12-page catalogue that brings together its range of high performance LED and metal halide light sources proven to provide the best possible illumination for your microscopy work.
Regardless of microscopy technique, high quality imaging requires high performance illumination in order to obtain the best possible results. Prior Scientific has designed a range of precisely engineered, reliable and long lasting light sources tailored to the exacting requirements of scientists across a broad range of disciplines. The new catalogue details Prior’s expanding range of LED illumination sources that offer many advantages for brightfield, DIC, phase contrast and fluorescence microscopy...
For the vast number of scientists that undertake handheld pipetting protocols - INTEGRA has produced a highly informative illustrated 'Best Practices' guide.
Drawing upon decades of pipetting experience - INTEGRA has compiled an unbiased series of hints and tips to help you improve your handheld pipetting. Expert advice is provided in areas including before you start, how to pipette and optimising pipetting performance. Each area of best pipetting practice discussed is backed up with an explanation of why this produces optimal results.
Following the recent addition of a number of products to the Lab M Listeria testing portfolio, the whole range can now be viewed in a single flyer, available on the Lab M website.
The document, ‘Listeria solutions… whatever your method’, clearly shows that whichever testing method users subscribe to, whatever the lab size, and whether they prefer dehydrated culture media (DCM) or a pre-prepared approach, Lab M has products to suit. Over the last year, Lab M has translated its expertise in developing and manufacturing DCM into a number of convenience products to suit the varying needs of customers, including...
Established initially as SANYO-Gallenkamp in 1990, the company evolved slowly, but solidly, and with a clear vision, into the modern, market-oriented, biomedical company that is now represented in every European country.
The world’s first lowest temperature freezer, a continuous contamination control concept for safer cell culture and the ultimate sample security VIP Dual Cool freezer are just a few of the many key, ground-breaking introductions that Panasonic has made over the last 25 years. And the articles in this Journal show how these Panasonic developments can help you in your daily challenge to do your work better, easier and more efficiently.
In a recent DECODED Online entry, Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, provides an overview of the CRISPR/Cas9 system to scientists looking to enhance their genome modification strategy in model organisms or cell lines.
The CRISPR/Cas9 system has rapidly become a leading method for genome editing. Faster and more efficient than other methods, the system is continually being improved. This entry informs researchers on the latest developments and highlight the potential of this evolving technology. Bringing together the latest information on CRISPR/Cas9, the piece links through to resources that cover the many advantages over other methods such as...
AMSBIO has launched, at the ‘Frontiers in Stem Cells & Cancer' EMBL-EMBO Symposium, a guide that illustrates a variety of organoids grown from different tissues by leading international research groups using BME 2 reduced growth factor extracellular matrix that is available from the company.
Organoids are organ-like structures that can be formed by 3D cell culture and differentiation of stem cells or organ progenitors. Organoids are capable of recapitulating aspects of organ function in in vitro. The current research and therapeutic potential of organoids include organogenesis models, drug testing, tumor / disease models, toxicity screening, personalised medicine and regenerative medicine / organ replacement. BME 2 reduced growth...
Freeman Technology, a global leader in powder characterisation, has published ‘The Value of Powder Testing’, the third in the company’s series of educational guides on powder characterisation for industrial applications.
The new booklet focuses on how to assess the economic benefits that a powder tester can deliver and explains how these may vary considerably depending on the instrumentation selected. All three guides, including, ‘An Introduction to Powders’ and ‘Choosing a Powder Tester’, are written in an easy to understand, straightforward style and are now available for download at http://www.freemantech.co.uk/_ebook/. The new guide addresses...
Application guide for Tecan plate washers offers an easy route to optimized results
Tecan’s recently published Application guide for Tecan plate washers puts information at your fingertips, allowing users of its popular HydroSpeed™ and HydroFlex™ instruments to optimize their assays more easily and simply. Whether you are performing ELISAs, vacuum filtration, magnetic bead- or cell-based assays, the guide contains everything you need to know about Tecan washers....
Read MoreCLSI Publishes a New Document on Process ManagementApr 13, 2015
The Clinical and Laboratory Standards Institute (CLSI) has published a new document titled Process Management (QMS18-Ed1).
This guideline describes four requirements for managing laboratory processes and provides suggestions for effectively meeting regulatory and accreditation requirements, optimizing efficient use of resources, and contributing to patient safety and positive outcomes. This new document outlines Process Management, one of the 12 quality system essentials (QSEs) described in CLSI document QMS01, which defines a structured approach to...
The Clinical and Laboratory Standards Institute (CLSI) has published Molecular Diagnostic Methods for Infectious Diseases (MM03-Ed3).
This report addresses topics relating to clinical applications, amplified and nonamplified nucleic acid methods, selection and qualification of nucleic acid sequences, establishment and evaluation of test performance characteristics, inhibitors, and interfering substances, controlling false-positive reactions, reporting and interpretation of results, quality assurance, regulatory issues, and recommendations for manufacturers and clinical laboratories...
The Clinical and Laboratory Standards Institute (CLSI) has published Mass Spectrometry for Androgen and Estrogen Measurements in Serum (C57-Ed1).
This document is intended to aid the laboratorian in developing appropriate procedures for the use of mass spectrometry in the measurement of androgens and estrogens. C57 provides details specific to androgen and estrogen measurement procedures with respect to preexamination (preanalytical) considerations, mass spectrometry (MS) technologies, measurement procedure and run validation, as well as postexamination...
Biopharma Process Systems has written a free guide which provides a grounding in the science, tips on avoiding common evaporation mistakes, and a look at the latest developments in evaporation technology.
Solvent removal by evaporation is an essential process for sample preparation. Many sample formats and solvents are used with no single technique providing a universal solutions. Despite the variety if specifics evaporation is well-understood and relatively uncomplicated. But while it’s vital to so many applications it’s rare to find an evaporation expert in a laboratory, and many facilities use systems that are slow and cumbersome simply because they have always been used....
FLIR Systems have published a new handbook, available as an interactive pdf or iBook for iPad, that allows you to discover thermal imaging applications advances that researchers are making around the world.
Researchers and engineers are using FLIR research grade thermal imaging cameras every day to solve challenges that are difficult by other means, or to improve on, or replace time consuming techniques like IR thermocouples. Thermal imaging cameras provide non-contact temperature measurement, image through some materials or make the invisible visible using spectral filtering, capture high speed thermal events, synchronize...
Optical Surfaces Ltd. has published a new guide to provide scientists and engineers with expert advice on maintaining the performance of their aluminum coated optics.
After a time, depending on the environment in which coated optics are used, they may become contaminated with dust or stained. Dust and stains can cause scattering, and impurities on the surface of the optics can react with incident light resulting in damage to the optical coating. Starting from the premise “If it’s not dirty don’t clean it” the new guide describes a simple to follow 5-step progressive process for cleaning coated optics in a clean, low dust environment...
The Clinical and Laboratory Standards Institute (CLSI) has published Quality System Regulation for Laboratory-Developed Tests: A Practical Guide for the Laboratory.
This guide converts the requirement complexities of US Food and Drug Administration (FDA) regulations into plain language, offering intuitive assistance on how to conform to the Quality System Regulation (QSReg), 21 CFR 820, when creating laboratory-developed tests (LDTs). This CLSI practical guide can help laboratorians learn how to address the new demands, beyond the Clinical Laboratory Improvement Amendments...
Viscometers, Rheometers, Texture Analyzers and Powder Flow Testers
Brookfield Engineering Laboratories has released their new 2015 full-color catalog with complete details on all product lines. The 2015 Catalog introduces the new DV1 Viscometer, Brookfield’s lowest-cost, continuous sensing digital viscometer. Enhancements to the top-of-the-line RST Rheometer for quick, automatic gap setting on cone/plate models are announced. Several new and improved texture fixtures for measuring tablet strength, cheese stringiness, and hair...
The commercial pressures on research laboratories to improve efficiency and generate savings has led Scientific Laboratory Supplies Ltd (SLS), the UK’s largest independent British-owned supplier of scientific equipment, chemicals and consumables, to launch its first catalogue devoted to essential Cleanroom products.
The catalogue has been produced in partnership with the UK’s leading specialist cleanroom supplier Micronclean and brings together market-leading products at competitive prices to serve the needs of cleanroom facilities managers. Lee Jenkins, Supply Development Manager for SLS says “The driving forces for technological changes in cleanroom operation centre on saving time, lowering costs and reducing contamination risks. This is why...
The Clinical and Laboratory Standards Institute (CLSI) released a new edition of its annual supplement Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Fifth Informational Supplement (M100-S25).
This document provides the revised breakpoints, new testing recommendations, and reporting changes needed to incorporate into routine practice to improve detection and reporting of antimicrobial resistance. This year, M100-S25 has published in tandem with its two related methodology standards, Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard—Twelfth Edition (M02-A12) and Methods for...
The Clinical and Laboratory Standards Institute (CLSI) has published a new document, Planning for Laboratory Operations During a Disaster; Approved Guideline (GP36-A).
This document provides guidance for laboratory and health care leadership for development, implementation, and sustainment of effective emergency preparedness plans (all hazards) supporting nonanalytical components of clinical and public health laboratory services that may pertain to various natural and manmade disasters. This document follows a preparedness planning process recommended by business continuity planning professionals, which is intended to take the...
Chromatrap® ChIP kits use revolutionary spin columns or microplates which contain discs of an inert, porous polymer to which protein A or G has been covalently attached. This patented format is unique. During an assay, the chromatin/antibody complex is selectively retained by the disc. Flushing with three buffers and an elution step are all that is required to obtain the selectively enriched DNA, making Chromatrap® more efficient in the laboratory. With a fast processing time of...
‘Quality Solutions for Inhaler Testing, 2015 Edition’ includes detailed information on regulatory requirements and highlights pertinent new additions to the company’s extensive inhaled product testing range. It can be downloaded freely from the Copley Scientific website (www.copleyscientific.com) with print versions available on request from sales@copleyscientific.co.uk. “We know that our customers value help with understanding the testing requirements for OINDPs, which...
Leading provider of hygiene, safety and productivity solutions, the KIMBERLY-CLARK PROFESSIONAL* Scientific business has published the second in an ongoing series of health and safety focused mini-guides. Offering bite-sized learning on health, safety and personal protection in the laboratory, these mini-guides are designed to present complex information in a more handy, easy-to-absorb and engaging format. To download free copies...
Regardless of microscopy technique, high quality imaging requires high performance illumination in order to obtain the best possible results. Prior Scientific has designed a range of precisely engineered, reliable and long lasting light sources tailored to the exacting requirements of scientists across a broad range of disciplines. The new catalogue details Prior’s expanding range of LED illumination sources that offer many advantages for brightfield, DIC, phase contrast and fluorescence microscopy...
Drawing upon decades of pipetting experience - INTEGRA has compiled an unbiased series of hints and tips to help you improve your handheld pipetting. Expert advice is provided in areas including before you start, how to pipette and optimising pipetting performance. Each area of best pipetting practice discussed is backed up with an explanation of why this produces optimal results.
The document, ‘Listeria solutions… whatever your method’, clearly shows that whichever testing method users subscribe to, whatever the lab size, and whether they prefer dehydrated culture media (DCM) or a pre-prepared approach, Lab M has products to suit. Over the last year, Lab M has translated its expertise in developing and manufacturing DCM into a number of convenience products to suit the varying needs of customers, including...
The world’s first lowest temperature freezer, a continuous contamination control concept for safer cell culture and the ultimate sample security VIP Dual Cool freezer are just a few of the many key, ground-breaking introductions that Panasonic has made over the last 25 years. And the articles in this Journal show how these Panasonic developments can help you in your daily challenge to do your work better, easier and more efficiently.
The CRISPR/Cas9 system has rapidly become a leading method for genome editing. Faster and more efficient than other methods, the system is continually being improved. This entry informs researchers on the latest developments and highlight the potential of this evolving technology. Bringing together the latest information on CRISPR/Cas9, the piece links through to resources that cover the many advantages over other methods such as...
Organoids are organ-like structures that can be formed by 3D cell culture and differentiation of stem cells or organ progenitors. Organoids are capable of recapitulating aspects of organ function in in vitro. The current research and therapeutic potential of organoids include organogenesis models, drug testing, tumor / disease models, toxicity screening, personalised medicine and regenerative medicine / organ replacement. BME 2 reduced growth...
The new booklet focuses on how to assess the economic benefits that a powder tester can deliver and explains how these may vary considerably depending on the instrumentation selected. All three guides, including, ‘An Introduction to Powders’ and ‘Choosing a Powder Tester’, are written in an easy to understand, straightforward style and are now available for download at http://www.freemantech.co.uk/_ebook/. The new guide addresses...
This guideline describes four requirements for managing laboratory processes and provides suggestions for effectively meeting regulatory and accreditation requirements, optimizing efficient use of resources, and contributing to patient safety and positive outcomes. This new document outlines Process Management, one of the 12 quality system essentials (QSEs) described in CLSI document QMS01, which defines a structured approach to...
Solvent removal by evaporation is an essential process for sample preparation. Many sample formats and solvents are used with no single technique providing a universal solutions. Despite the variety if specifics evaporation is well-understood and relatively uncomplicated. But while it’s vital to so many applications it’s rare to find an evaporation expert in a laboratory, and many facilities use systems that are slow and cumbersome simply because they have always been used....
Researchers and engineers are using FLIR research grade thermal imaging cameras every day to solve challenges that are difficult by other means, or to improve on, or replace time consuming techniques like IR thermocouples. Thermal imaging cameras provide non-contact temperature measurement, image through some materials or make the invisible visible using spectral filtering, capture high speed thermal events, synchronize...
After a time, depending on the environment in which coated optics are used, they may become contaminated with dust or stained. Dust and stains can cause scattering, and impurities on the surface of the optics can react with incident light resulting in damage to the optical coating.
Brookfield Engineering Laboratories has released their new 2015 full-color catalog with complete details on all product lines. The 2015 Catalog introduces the new DV1 Viscometer, Brookfield’s lowest-cost, continuous sensing digital viscometer. Enhancements to the top-of-the-line RST Rheometer for quick, automatic gap setting on cone/plate models are announced. Several new and improved texture fixtures for measuring tablet strength, cheese stringiness, and hair...
The catalogue has been produced in partnership with the UK’s leading specialist cleanroom supplier Micronclean and brings together market-leading products at competitive prices to serve the needs of cleanroom facilities managers. Lee Jenkins, Supply Development Manager for SLS says “The driving forces for technological changes in cleanroom operation centre on saving time, lowering costs and reducing contamination risks. This is why...
This document provides guidance for laboratory and health care leadership for development, implementation, and sustainment of effective emergency preparedness plans (all hazards) supporting nonanalytical components of clinical and public health laboratory services that may pertain to various natural and manmade disasters. This document follows a preparedness planning process recommended by business continuity planning professionals, which is intended to take the...