Scientists working on cancer research are now able to use a new non-adherent cell culture surface to support the formation of consistent cancer spheroids in vitro, simulating the three-dimensional (3D) structures of tumor growth and providing a better model system for studying tumor cell progression and the efficacy of anticancer agents than two-dimensional (2D) systems and other surfaces.
The new Thermo Scientific Nunclon Sphera is a polymer-coated surface with very low-binding characteristics, which is designed to allow many different cell types to grow in suspension consistently with virtually no cell attachment. An alternative to commonly used non-treated surfaces, the Nunclon Sphera non-adherent surface is especially important for researchers seeking to cultivate cancer and stem cell spheroids, since the product is able to grow uniform and dependable spheres....
Read MoreHigh-Throughput Label-Free Interaction Analysis made Easy with EzPlexMay 1, 2014
HORIBA Scientific is pleased to announce the launch of EzPlex, the new flagship instrument of the label-free molecular interaction platform based on Surface Plasmon Resonance imaging (SPRi).
EzPlex gives quantitative and qualitative information on multiplex molecular interaction assays involving oligonucleotides, oligosaccharides, proteins, antibodies, aptamers or even cells and bacteria. The imaging capability dramatically enhances the throughput of conventional SPR and allows from few up to several hundred molecular interactions to be screened and characterized simultaneously. Interaction kinetic profiles can be obtained within minutes and give precious data about binding strength, kinetics and affinity....
VICI’s Microvolume Diaphragm Valve is designed for trouble-free use in applications requiring minimal maintenance and maximum lifetime, making it the ideal choice for the process industry, automated lab analyzers, and continuous-monitoring environmental analyses.
Three configurations are available: a 4 port internal loop sample injector; a 6 port external loop sampling/switching valve; and the industry’s first 10 port multifunctional diaphragm valve. Lifetime for the DV22 can exceed 1,000,000 cycles at ambient temperature/300 psi or 500,000 cycles at 175°C/300 psi. The standard valve is for applications in which the sample is above ambient pressure, but it can also be used with sub-ambient pressures, such as when the sample is pulled through the valve by vacuum....
The RSC 350 laboratory autoclave from specialist autoclave manufacturer Priorclave is proving to be the ideal choice for those laboratories in the food and drink, dairy, pharmaceutical, agriculture, education, healthcare and research sectors looking to achieve high-throughput sterilising procedures or have a requirement to process large bulky items.
The popularity of this front-loading autoclave is driven by a design that offers a large sterilising chamber yet requires a relatively small footprint and is by far one of the easiest to install since it is castor mounted for easy positioning and pass through a standard door. With a 350 litre capacity chamber the RCS 350 laboratory autoclave is the perfect choice where tall, small and bulky items need to be sterilised since the rectangular chamber will accommodate many differing media types and sizes side-by-side....
Xpert HPV is the Only Test Capable of Reporting High-risk Human Papillomavirus DNA in Captured Cervical Cells
The release of Xpert® HPV, a 60-minute test for cervical cancer-related human papillomaviruses to be marketed as a CE IVD product under the European Directive on In Vitro Diagnostic Medical Devices. The test runs on Cepheid’s GeneXpert® System, the world’s leading molecular diagnostic platform. Xpert HPV is a multiplexed test that targets the E6 and E7 oncogenes of 14 cancer-related HPV types and specifically calls out high-risk types 16 and 18/45 in separate detection channels, with 11 other high-risk types detected in a combined channel....
Read MoreJ G Finneran Introduces the 300Apr 28, 2014
Chromatography sample vials and inserts with one-piece design provides a safe, secure sample containment for use with robotic arm autosamplers
Here is a unique product for researchers tasked with managing a lot of chromatography sample vials in their laboratories: the new 300µL Interlocked R.A.M. (Robotic Arm Machine) Vial with 9mm Thread Finish, by J.G. Finneran Associates. Composed of a clear or amber Type I borosilicate glass, the vial and insert are fused together keeping the insert permanently in place. This design enables accurate automated injection, and eliminates contamination risk around the seam or space between the neck of the vial and the insert....
Read MoreJenwayApr 28, 2014
Jenway offers an extensive range of laboratory meters for the measurement of dissolved oxygen, pH and conductivity, which are all covered by a three year warranty.
Jenway’s advanced pH and conductivity laboratory meters have automatic standard recognition to ensure accuracy of results and can be calibrated using 1, 2 or 3 calibration points. The laboratory conductivity meters have additional modes for salinity and resistivity, adding to the flexibility of these advanced meters. The 3520 dynamic pH/mV meter offers research grade specifications with a comprehensive range of features and functions, making it suitable for the broadest range of research, general laboratory, QC and GLP based applications...
JULABO presents the PRESTO® model series W91 and W92: the particularly strong, highly dynamic temperature control systems of the newly developed PRESTO® family.
They unite high efficiency with unequaled power e.g. for reactor systems, mini plants, pilot plants, Kilo labs, vacuum chambers and many more. The PRESTO® W91 and W92 cover a working temperature range from -92°C to +250 C. They provide up to 31 kW cooling capacity and up to 36 kW heating capacity, and they are robust and reliable even at high room temperatures up to +40 C. Highly efficient components in all instruments compensate for exothermic and endothermic reactions extremely fast...
Read MoreNew Cryostat Offers High-Quality, Efficient Frozen SectioningApr 28, 2014
A new manual cryostat offers scientists improved functionality and ergonomics, ensuring efficient, high-quality frozen sectioning.
The Thermo Scientific HM525 NX is a routine clinical cryostat that has 27 cooled specimen positions, including 4 fast freeze positions, allowing a high degree of flexibility when managing specimens.
“Pathologists rely on quick turnaround time and excellent sectioning quality from their cryostat,” said Richard Vernon, commercial product manager, anatomical pathology, for Thermo Fisher Scientific. “Our HM525 NX cryostat gives them the functionality and control to achieve diagnosis rapidly.”..
Drawing upon a wealth of experience of working with a wide range of 3D cell culture procedures and formats - AMSBIO has produced an extensive 48-page handbook for research scientists looking to culture cells in more physiologically relevant environments.
Over the past two decades, many researchers have actively sought ways to culture cells in 3D. The conclusion reached by many researchers is that there is no single optimal solution, each cell type needs a different environment and many biological processes may need specific methods to study them. Leading the field in the provision of solutions for 3D Cell Culture, AMSBIO’s scientists have distilled the best technologies into a useful guide....
BioTek’s MultiFlo™ FX is now available with optional RAD™ (Random Access Dispense) technology to further extend its application range and flexibility.
RAD technology offers single-channel dispensing to random individual microplate wells along with rapid reagent dispensing into large volume wells of 6- to 24- well microplates. MultiFlo FX can also be separately configured with an optional wash module for 6- to 384-well plates....
The demand for ever-increasing throughput means that many laboratories are looking for solutions to increase the capacity of their automated systems.
Tecan has created Nested LiHa Disposable Tips specifically to meet this need, allowing up to five racks of the new 350 μl tips to be stacked on a single SLAS-format carrier. This space-saving solution allows optimized use of deck space, minimizing the need for manual intervention and increasing walkaway time for Freedom EVO® liquid handling workstations....
Porvair Sciences has announced a new video that provides an informative introduction to the Ultravap Mistral - a next generation robot-compatible dry down station designed to remove the 'bottleneck' of solvent evaporation from microplates.
Drawing upon Porvair’s market leading position in nitrogen blow down evaporation – the UltraVap Mistral offers a simple, turnkey solution for integrating an automatic dry down step into your automated liquid handling protocol. The UltraVap Mistral is fully optimised to work with robotic liquid handling systems from suppliers including Beckman, Hamilton and Tecan and features a “shuttle” design capable of serving and retrieving microplates to and from the robot deck without further need for off-deck handling....
Read MoreLinkApr 24, 2014
Link Technologies Ltd, an ISO 9001:2008 certified specialist oligonucleotide reagent manufacturer, has expanded its range of lipophilic modifiers for the effective delivery of oligonucleotides into cells.
As oligos continue to be of interest in drug discovery, offering exciting potential as therapeutic agents, there is an increasing demand for improved oligo delivery techniques. Link’s proven collection of lipophilic oligo modification reagents, which include cholesterol and tocopherol modifiers, now also includes 5’-Palmitate-C6-CE Phosphoramidite....
Two new xGen® next generation sequencing panels to be launched
Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, is extending its portfolio of NGS panels with the addition of the xGen® Inherited Disease and Pan-Cancer Panels. Adding these to the xGen AML Panel which was launched at the end of last year, IDT now offers a range of panels for deep sequencing that can be supplemented to cover a comprehensive range of diseases....
Merck Millipore, the Life Science division of Merck, today announced the release of five new immunoassay kits designed specifically for use on the Gyrolab™ workstation.
The new, fully qualified GyroMark™ HT kits from Merck Millipore will enable clinical researchers and drug developers to generate valuable research data much faster than typical ELISA kits. Traditional ELISAs can consume significant time, sample and reagents. With the fully automated, walk-away system from Gyros, approximately 500 samples can be analyzed within four hours....
OGT releases new CytoSure™ Interpret Software to enhance CNV detection
Oxford Gene Technology (OGT), The Molecular Genetics Company, is pleased to announce the latest version (4.5.3) of its class-leading CytoSure™ Interpret Software. Complimentary with all CytoSure array purchases, CytoSure Interpret Software is a powerful and easy-to-use package for the analysis of aCGH data, the gold-standard for copy number variation (CNV) detection. Offering an impressive combination of advanced features, including Automatic Aberration Classification, the software allows the choice of standardised or customised user-defined data analysis....
FRITSCH Planetary Mills classic line are most effective for rapid loss-free and reproducible ultra-fine grinding of hard, medium-hard, brittle and fibrous materials dry or in suspension, for mixing and homogenising as well as for mechanical alloying/activation in materials research.
Samples can be processed from a few milligrams to several kilograms at a wide range of fineness levels down to less than 1 μm. They are absolutely reliable, especially easy to operate and clean. Matching grinding parts of various materials are also available to provide maximum protection against undesired contamination of the samples.
Merck Millipore, the Life Science division of Merck, today introduced a new recombinant protein purification protocol that combines lysis and purification into a single step.
The condensed workflow can be completed in about 45 minutes, reducing processing time by 75% compared to traditional techniques, while delivering high yield and purity. The new protocol requires significantly less hands-on time than the conventional workflow, provides greater consistency and results in more reproducible yields....
Tecan offers a wide range of laboratory automation solutions for mass spectrometry (MS) sample preparation, ensuring there is a system to meet your workflow and throughput needs.
From solid phase extraction and liquid-liquid extraction to protein precipitation and straightforward ‘dilute and shoot’ methods, Tecan provides seamless automation of routine sample preparation applications, helping to alleviate major bottlenecks for many laboratories. Recent advances in MS instrumentation have led to an increasing number of laboratories choosing this technology for a wide range of applications. However, sample preparation techniques have not enjoyed the same rate of development, leading to processing bottlenecks and reducing overall productivity. Automation of routine sample preparation can alleviate these problems, reducing hands-on time and increasing throughput...
Micronic has launched a new externally threaded 3.00ml tube that provides a fully traceable storage solution for tissue samples.
With a unique 2-dimensional Data Matrix code laser encrypted on the tube bottom, and large human readable code on the tube sidewall – Micronic 3.00ml tissue tubes provide easy and unambiguous identification and storage of your donor and transplant samples. The unique 2D code identifies the sample, its coordinates within a 24-tube storage rack, the particular rack and the location of the rack in your freezer. For highly accurate and reliable results - Micronic 3.00ml tissue tubes are produced from medical-grade polypropylene....
The JXN-26 Enhances Workflows in Research and Bioprocessing
Combining high performance and application versatility, Avanti JXN-26 centrifuges from Beckman Coulter Life Sciences offer laboratories an intuitive interface and advanced data management features that expand functionality and flexibility to free user time in research and bioproduction. The instruments can be run from an Apple iOS or Android device using MobileFuge, the only mobile application available to run and manage laboratory centrifuges....
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Three configurations are available: a 4 port internal loop sample injector; a 6 port external loop sampling/switching valve; and the industry’s first 10 port multifunctional diaphragm valve. Lifetime for the DV22 can exceed 1,000,000 cycles at ambient temperature/300 psi or 500,000 cycles at 175°C/300 psi. The standard valve is for applications in which the sample is above ambient pressure, but it can also be used with sub-ambient pressures, such as when the sample is pulled through the valve by vacuum....
The popularity of this front-loading autoclave is driven by a design that offers a large sterilising chamber yet requires a relatively small footprint and is by far one of the easiest to install since it is castor mounted for easy positioning and pass through a standard door. With a 350 litre capacity chamber the RCS 350 laboratory autoclave is the perfect choice where tall, small and bulky items need to be sterilised since the rectangular chamber will accommodate many differing media types and sizes side-by-side....
The release of Xpert® HPV, a 60-minute test for cervical cancer-related human papillomaviruses to be marketed as a CE IVD product under the European Directive on In Vitro Diagnostic Medical Devices. The test runs on Cepheid’s GeneXpert® System, the world’s leading molecular diagnostic platform. Xpert HPV is a multiplexed test that targets the E6 and E7 oncogenes of 14 cancer-related HPV types and specifically calls out high-risk types 16 and 18/45 in separate detection channels, with 11 other high-risk types detected in a combined channel....
Here is a unique product for researchers tasked with managing a lot of chromatography sample vials in their laboratories: the new 300µL Interlocked R.A.M. (Robotic Arm Machine) Vial with 9mm Thread Finish, by J.G. Finneran Associates. Composed of a clear or amber Type I borosilicate glass, the vial and insert are fused together keeping the insert permanently in place. This design enables accurate automated injection, and eliminates contamination risk around the seam or space between the neck of the vial and the insert....
Jenway’s advanced pH and conductivity laboratory meters have automatic standard recognition to ensure accuracy of results and can be calibrated using 1, 2 or 3 calibration points. The laboratory conductivity meters have additional modes for salinity and resistivity, adding to the flexibility of these advanced meters. The 3520 dynamic pH/mV meter offers research grade specifications with a comprehensive range of features and functions, making it suitable for the broadest range of research, general laboratory, QC and GLP based applications...
They unite high efficiency with unequaled power e.g. for reactor systems, mini plants, pilot plants, Kilo labs, vacuum chambers and many more. The PRESTO® W91 and W92 cover a working temperature range from -92°C to +250 C. They provide up to 31 kW cooling capacity and up to 36 kW heating capacity, and they are robust and reliable even at high room temperatures up to +40 C. Highly efficient components in all instruments compensate for exothermic and endothermic reactions extremely fast...
Over the past two decades, many researchers have actively sought ways to culture cells in 3D. The conclusion reached by many researchers is that there is no single optimal solution, each cell type needs a different environment and many biological processes may need specific methods to study them. Leading the field in the provision of solutions for 3D Cell Culture, AMSBIO’s scientists have distilled the best technologies into a useful guide....
Tecan has created Nested LiHa Disposable Tips specifically to meet this need, allowing up to five racks of the new 350 μl tips to be stacked on a single SLAS-format carrier. This space-saving solution allows optimized use of deck space, minimizing the need for manual intervention and increasing walkaway time for Freedom EVO® liquid handling workstations....
Drawing upon Porvair’s market leading position in nitrogen blow down evaporation – the UltraVap Mistral offers a simple, turnkey solution for integrating an automatic dry down step into your automated liquid handling protocol. The UltraVap Mistral is fully optimised to work with robotic liquid handling systems from suppliers including Beckman, Hamilton and Tecan and features a “shuttle” design capable of serving and retrieving microplates to and from the robot deck without further need for off-deck handling....
As oligos continue to be of interest in drug discovery, offering exciting potential as therapeutic agents, there is an increasing demand for improved oligo delivery techniques. Link’s proven collection of lipophilic oligo modification reagents, which include cholesterol and tocopherol modifiers, now also includes 5’-Palmitate-C6-CE Phosphoramidite....
The new, fully qualified GyroMark™ HT kits from Merck Millipore will enable clinical researchers and drug developers to generate valuable research data much faster than typical ELISA kits. Traditional ELISAs can consume significant time, sample and reagents. With the fully automated, walk-away system from Gyros, approximately 500 samples can be analyzed within four hours....
Oxford Gene Technology (OGT), The Molecular Genetics Company, is pleased to announce the latest version (4.5.3) of its class-leading CytoSure™ Interpret Software. Complimentary with all CytoSure array purchases, CytoSure Interpret Software is a powerful and easy-to-use package for the analysis of aCGH data, the gold-standard for copy number variation (CNV) detection. Offering an impressive combination of advanced features, including Automatic Aberration Classification, the software allows the choice of standardised or customised user-defined data analysis....
The condensed workflow can be completed in about 45 minutes, reducing processing time by 75% compared to traditional techniques, while delivering high yield and purity. The new protocol requires significantly less hands-on time than the conventional workflow, provides greater consistency and results in more reproducible yields....
From solid phase extraction and liquid-liquid extraction to protein precipitation and straightforward ‘dilute and shoot’ methods, Tecan provides seamless automation of routine sample preparation applications, helping to alleviate major bottlenecks for many laboratories. Recent advances in MS instrumentation have led to an increasing number of laboratories choosing this technology for a wide range of applications. However, sample preparation techniques have not enjoyed the same rate of development, leading to processing bottlenecks and reducing overall productivity. Automation of routine sample preparation can alleviate these problems, reducing hands-on time and increasing throughput...
With a unique 2-dimensional Data Matrix code laser encrypted on the tube bottom, and large human readable code on the tube sidewall – Micronic 3.00ml tissue tubes provide easy and unambiguous identification and storage of your donor and transplant samples. The unique 2D code identifies the sample, its coordinates within a 24-tube storage rack, the particular rack and the location of the rack in your freezer. For highly accurate and reliable results - Micronic 3.00ml tissue tubes are produced from medical-grade polypropylene....
Combining high performance and application versatility, Avanti JXN-26 centrifuges from Beckman Coulter Life Sciences offer laboratories an intuitive interface and advanced data management features that expand functionality and flexibility to free user time in research and bioproduction. The instruments can be run from an Apple iOS or Android device using MobileFuge, the only mobile application available to run and manage laboratory centrifuges....