Nanoliter-scale kit rapidly and easily detects and quantifies host cell proteins from Chinese hamster ovary cells

Gyros AB, a pioneer in miniaturizing and automating immunoassays at nanoliter-scale, today announced the introduction of its Gyrolab™ CHO-HCP Kit 1. The new kit detects and quantifies host cell proteins (HCP) from Chinese hamster ovary (CHO) cells used in bioprocessing of biotherapeutics. HCP are measured throughout the production process, as they may affect the safety and efficacy of the biotherapeutic....

As we all know, many cellular activities are controlled by post-translational modifications, the study of which is stuck by the lack of specific reagents due greatly to their nature of ubiquitousness and non-immunogenicity. With great efforts, Creative Biolabs has developed PTM-Ab™ technology, which offers services for post-translational modification specific antibody discovery.

A new YouTube video published by Laboratory Information Management Systems (LIMS) specialist, Autoscribe, provides a practical demonstration of the ease of configuration of the Matrix Gemini LIMS.

Since each individual laboratory is a little different from its nearest equivalent and often vastly different from laboratories in different industries, Matrix Gemini’s unique OneTime™configuration tools provide the flexibility to ensure that customers are not forced into a particular system design. These versatile configuration tools offer a ‘drag and drop’ approach to build a personalised user interface with no impact on the underlying core...

Clear, bright broad spectrum illumination – without the mercury! 

There’s now a better and safer alternative to a high-pressure mercury or metal-halide light source for fluorescence microscopy. Available from Alpha Laboratories, the pE-300white unit from CoolLED offers broad spectrum LED illumination for general use in fluorescence applications. With a comprehensive range of microscope adaptors, it can easily be fitted to most microscopes, old or new, providing a safe, convenient and economical illumination system...

LaVison BioTec, developers of advanced microscopy solutions for the life sciences, announces the dates and venue of the first international users' meeting on their UltraMicroscope light sheet microscopy products. 

The first LaVision BioTec UltraMicroscope User Meeting will take place at the Max Planck Institute for Molecular Biomedicine in Münster, 21-22 September. Participants are cordially invited to join with all active and prospective UltraMicroscope users in a forum on the latest developments in light sheet microscopy. With this scientific gathering, LaVision BioTec is fostering the exchange of thoughts, experiences and views on this emerging and very active...

Chromatography specialists from Malvern Instruments will present a reliable optimized solution for lignin characterization at a series of upcoming conferences in 2015, the first of which is Nordic Polymer Days, Denmark, June 1 – 3.

Lignin is a vital industrial polymer but presents significant challenges when it comes to measurement of the properties that define its performance. Through experimental study Malvern has identified the best strategy to apply when using gel permeation/size exclusion chromatography (GPC/SEC) to secure reliable information. The results of this work will also be presented at the 13th Annual UNESCO/IUPAC Conference on...

LaVison BioTec, developers of advanced microscopy solutions for the life sciences, report on the research of Dr Matteo Iannacone of the San Raffaele Scientific Institute in Milan where intravital microscopy is being applied to the study of host-viruses and associated immune responses. 

Matteo Iannacone, MD, PhD is the Group Leader in the Division of Immunology at the San Raffaele Scientific Institute, Milan, Italy. His research program seeks to dissect the complex dynamics of host-virus interactions with a particular focus on the development and function of adaptive immune responses. Since it is still beyond the reach of even the most sophisticated in vitro methodology to simulate the complex interplay of physical...

EKF Diagnostics, the global diagnostics company, announces that it has introduced the Stanbio Chemistry Procalcitonin (PCT) LiquiColor^® Assay.

This new test enables the quantitative determination of PCT in serum samples, EDTA or lithium heparin plasma samples by latex enhanced immunoturbidimetric methodology. Procalcitonin is a marker for bacterial infection and sepsis and has been recognized as an important adjunct marker in the diagnosis of sepsis*. The new Stanbio Chemistry Procalcitonin (PCT) LiquiColor^® Assay is fast, accurate and convenient. The test provides...

Deben, leading providers of in-situ testing stages together with innovative accessories and components for electron microscopy, report on the work of Microscopy & Histology Core Facility at the University of Aberdeen. 

The Microscopy and Histology Facility provide access to assorted technologies to researchers at the University of Aberdeen. One core technique is Transmission Electron Microscopy (TEM) which was recently upgraded with the installation of a new JEOL JEM-1400 plus TEM with AMT camera system from Deben. The current research done using this equipment is varied and includes samples such as bone cells, yeast cells and macrophages. Some...

AMSBIO has launched a new and exclusive biotinylated protein collection specially designed to simplify your research. 

Attaching biotin to proteins and other macromolecules is an established labelling method which allows specific detection of biotin-tagged molecules via anti-biotin antibody, avidin or streptavidin based reporter systems. Biotinylation reagents are available for targeting specific functional groups or residues, including primary amines, sulfhydryls, carboxyls and carbohydrates. Photoreactive biotin compounds that react nonspecifically...

UK-based MR Solutions demonstrate its latest commercially available cryogen-free multi-modality preclinical MRI imaging systems at the 23^rd Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM).

The preclinical range, which is commercially available, includes the cryogen-free 3T, 4.7T and 7T MRI systems. MR Solutions has developed multi-modality preclinical imaging systems so the need for separate systems is no longer necessary. PET-MRI and SPECT-MRI imaging modules can either be inserted or clipped-on according to system configuration. PET-MRI and SPECT-MRI imaging can be carried out with independent acquisition of data, or sequential acquisition, or simultaneous acquisition.

Glass Solutions has launched a range of jacketed reactor systems combining excellent value with reliable performance for process development, reaction optimization, or production applications.

Ideal for crystallizations, process work-ups, distillations and bioreactions, Glass Solutions Reactor Systems are designed for process development labs, kilo labs and pilot plants, and can be used in a diverse array of scientific disciplines, from the pharma and fine chemical industries to the flavor and fragrance, petrochemistry, and agrochemistry sectors. Chemically-resistant and simple to use, these robust, high quality systems are available in a wide range of benchtop or floor...

A new technical poster from Haydale Ltd. describes a cost-effective and repeatable method for characterisation of functionalised carbon nanomaterials.

Two key, but independent, problems facing the graphene industry are the requirement for chemical functionalisation (essential for homogenous dispersion and application) and the pressing need for reliable, cost-effective, rapid, easy-to-use and accurate characterisation techniques to determine the type and extent of functionalisation present on graphene material. Current chemical characterisation techniques including X-ray photoelectron spectroscopy...

Biobank operators can now benefit from a cost-effective, rapidly deployable sample management software package

Titian Software has drawn from its extensive knowledge of biobanking requirements to develop a cost-effective, pre-configured software package optimised for managing small to medium-sized sample collections. Ideal for biobanks, the new Mosaic Freezer Management software package is being launched at the International Society for Biological and Environmental Repositories (ISBER) 2015 annual meeting and exhibition, on May 5^th, 2015 in...

Scientists from the Hubrecht Institute and the University Medical Center Utrecht (UMC Utrecht) have developed a cell culture model of human colon cancer progression.

This model mimics the situation in patients more closely than any other colon cancer model so far. It enables researchers to study processes involved in colon cancer development and find new cancer drugs. The work by Clevers and colleagues is published online in Nature this week. Colon cancer is one of the most common and deadly forms of cancer. Like all cancers, it arises through an accumulation of DNA changes (mutations) in the...

The UK has the highest rate of Paget’s bone disease in the world, but now researchers from Liverpool John Moores University (LJMU), the Paget’s Association and Norton Priory Museum Trust are analysing ancient bones to better understand the progression of the disease, which may permit earlier diagnosis. 

Paget’s disease disrupts the normal cycle of bone renewal and repair, causing bones to become weakened and deformed. It is known to affect up to 1 in 12 older men and 1 in 20 women over the age of 80. But symptoms often only show at the later stages. As Diana Wilkinson, Specialist’s Paget’s Nurse, of the Paget’s Association explains: “The North West of England is known to have the highest prevalence of Paget’s disease and evidence of the...

Save Space and Effort  in Your Lab

Sartorius, a leading international laboratory and pharmaceutical equipment supplier, introduces a completely new concept for packaging pipette tips: FlexiBulk. The new bulk package with its well-organized tip arrangement saves valuable space in the laboratory. Compared with conventional bulk tip packages, the stackable FlexiBulk boxes take up to 40% less space, and cut packaging waste by nearly 50%, while reducing transportation costs and laboratories’ carbon footprint.

An international consortium of scientists led by a group from the University of Leicester has announced a new advance in understanding the mechanisms of cancer and how to target it more effectively with new treatments.

Two papers published in the same issue of the world-leading Journal of Cell Biology have arisen from research work led by Professor Andrew Fry at the University of Leicester.  Both papers suggest that new understanding of the mechanics of cell division can reveal new targets for cancer therapy. Professor Fry, who is Director of Research in the College of Medicine, Biological Sciences and Psychology at Leicester, said: “Together...

DELMIC develops and manufactures products which are focused on high performance, user friendly, integrated microscopy solutions.

Users of Delmic's SPARC technology from Stanford University and the FOM Institute AMOLF in the Netherlands are using cathodoluminescence measurements for nanoscale optical tomography. Engineers at Stanford University and the FOM Institute AMOLF, in the Netherlands, have developed a way to visualise the optical properties of objects that are thousands of times smaller than a grain of sand, in 3-D and with nanometer-scale...

Market leaders in temperature controlled microscopy, Linkam Scientific Instruments, have upgraded the control systems for their family of temperature stages with the launch of the new LinkPad 2 touch screen system.

The LinkPad 2 has been developed from Linkam's successful stand-alone series of controllers. The key motivation behind its release is to provide users with the ability to control complete experiments from an intuitive touch screen without the need for a PC. LinkPad 2 is now the flagship controller for the complete range of Linkam's temperature stages. These stages have been individually designed to meet specific applications needs, each calling...

Anachem are pleased to introduce RAININ's TerraRack, a revolutionary new concept in pipette tip racks. 

More than 50% lighter than conventional racks TerraRack does not compromise on strength and is completely recyclable. This single-use, disposable hinged-lid rack will not flex or bend when loading single or multichannel pipettes – even if excessive force is applied. Manufactured from PETE (polyethylene terephthalate), an exceptionally strong polyester most commonly used for water and soft-drinks bottles, the racks are exceptionally strong, crystal clear and 100% recyclable....

Soft tissue disorders like tumors are very difficult to recognize using normal X-ray machines.

There is hardly any distinction between healthy tissue and tumors. Researchers at the Technische Universität München (TUM) have now developed a technology using a compact synchrotron source that measures not only X-ray absorption, but also phase shifts and scattering. Tissue that is hardly recognizable using traditional X-ray machines is now visible. X-ray images have become an integral part of daily medical practice. Bones, for example...