Accurate and prompt diagnoses of Acute Lower Respiratory Tract Infections (LRTIs) is vital to ensure correct treatment plans are in place to improve patient management.
Immunosuppressed and paediatric patients are especially susceptible to severe disease progression, with sometimes fatal consequences. Dr Marcus Panning, physician and medical virologist, at The University Medical Centre Freiburg, has selected the Fast-track diagnostics Respiratory pathogens 21 assay to detect LRTIs and effectively diagnose vulnerable patients. Dr Panning sees a large proportion of patients in the immunosuppressed and paediatric patient groups. His laboratory...
Presents data on factors that affect the sensitivity of ADCC assays and discusses how to optimise methodology
Sartorius Stedim Biotech (SSB) BioOutsource today announced a new paper entitled, ‘As easy as ADCC’ has been published in the respected journal, European Biopharmaceutical Review. The article outlines the factors affecting the use of antibody-dependent cell-mediated cytotoxicity (ADCC) assays and discusses when to use different types of ADCC assays to guide the design of biosimilar drugs and determine comparability...
Xylem Inc. (NYSE: XYL), a leading global water technology company dedicated to solving the world’s most challenging water issues, has acquired HYPACK, Inc. a privately-owned company specializing in hydrographic survey software used in ocean, coastal and surface water applications, for approximately $18 million.
News of acquisition was shared in the Company’s third quarter earnings announcement. Other terms of the transaction were not disclosed. Located in Middletown, Connecticut, HYPACK is a leading provider of hydrographic survey data acquisition, processing, and visualization software. Used by government agencies, universities, and consultants, HYPACK products measure and map features in bodies of water in connection with maritime...
Clinicians from the University of Leicester and Leicester’s Hospitals lead an international clinical trial for patients with blood cancer
‘This drug has changed patients’ lives; from desperate and tired they are now leading a normal and really active life. This is hugely rewarding and encouraging.’ Dr Harriet Walter, University of Leicester Researchers from the University of Leicester and Leicester’s Hospitals have announced a breakthrough advance in the results of the world-first clinical trial with actual patients of a new drug to treat particular blood cancers....
Chromatrap®, a business unit of Porvair Sciences, has developed a new protocol that further extends the many advantages of its popular Chromatin Immunoprecipitation Sequencing (ChIP-seq) assay kits.
Key developments for the Chromatrap® ChIP-seq kit (version 1.2) include high quality chromatin can now be achieved via sonication or enzymatic digestion ; high and low abundant enrichment is possible from small chromatin samples ; improved antibody binding ; greater chromatin loading flexibility and the ability to use increased slurry volumes for difficult samples. Chromatrap’s® ChIP-seq kit uses solid state technology...
Trajan spearheading Turnbull Government’s new innovation agenda
Trajan Scientific and Medical has highlighted to Australia’s Prime Minister Malcolm Turnbull that “disruptive innovation” is well underway locally and globally, welcoming him to the company’s Global Headquarters in Melbourne, Australia, to showcase Trajan’s pioneering partnerships with academia and start-ups that are set to become a critical new pillar of the Australian economy. Chief Executive Officer of Trajan, Stephen Tomisich...
DataApex, a leader in chromatography software, and ACCHROM Instrument Technologies, a Chinese analytical instrument provider, announce the OEM cooperation. ACCHROM Technologies will market an OEM version of Clarity Chromatography Software under the name ACstation Chromatography Software.
ACstation includes control drivers for a complete S6000 HPLC system that cover pumps, auto sampler, column oven and a wide range of detectors that can support a variety of analytical applications. ACstation is available in both Chinese and English localizations. "We are happy that we have developed another OEM version that will be marketed primarily in China. A fast growing Chinese market is important for us and we are proud that Clarity Chromatography Software that has a Chinese...
Chromatography Resins Market in Drug Discovery by Technique (Ion Exchange, Affinity (Protein A, G & L), Hydrophobic Interaction, Size Exclusion, Multi Modal and Others) & Geography - Global Market Trends & Forecasts to 2020
The market for chromatography resins in drug discovery application is estimated at $238.07 Million in 2014 and is projected to grow at a CAGR of 7.0% between 2015 and 2020. The chromatography resins for drug discovery can be made of natural polymers, synthetic polymers or inorganic materials with ligands attached to them. This report on chromatography resins market in drug discovery covers all major regions such as...
Horizon’s new Reference Standards support the development and optimization of cell-free DNA based assays
Horizon Discovery Group plc (LSE:HZD) (Horizon), the international life science company supplying research tools and services to organizations engaged in genomics research and the development of personalized medicines, announces the introduction of its cell free DNA (cfDNA) HDx™ Reference Standards. The new Reference Standards support the development and optimization of cfDNA assays, which are emerging as an important tool for non-invasive liquid biopsies.
Scientists have developed a blood test that can identify key mutations driving resistance to a widely used prostate cancer drug, and identify in advance patients who will not respond to treatment.
The new research paves the way for information from a blood test to inform prostate cancer treatment in future, with only those patients whose cancers are free of resistance mutations taking the drug, abiraterone. The study is also a proof of principle that tests for cancer DNA in the bloodstream can be used to detect drug resistance mutations – allowing patients who will not benefit from one drug to be given an alternative treatment instead...
Inward investment into the knowledge economy sees more than £1.5million go to pioneering work that impacts on health
The University of Leicester has been awarded over £1.5million in order to advance knowledge and understanding in three key areas that impact on health. The funding has come from the Biotechnology and Biological Sciences Research Council (BBSRC), which leads world-class 21st century bioscience, promoting innovation in the bioeconomy and realising benefits for society within and beyond the UK. BBSRC support around 1600 scientists...
BioTek Instruments proudly welcomes Dr. Frank Siefert as General Manager of BioTek Germany and the company’s European Coordination Center, which provides service applications and technical support throughout the continent.
Dr. Siefert will be responsible for managing day-to-day operations in Germany and implementing local actions that align with the Company’s global business strategies and growth plans. “Dr. Siefert brings the right blend of market and technology knowledge along with a drive for growth,” noted Peter Weith, BioTek’s Vice President of Marketing, Sales & Service. “We are confident that under his guiding leadership, we can continue our...
Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their temperature controlled stages applied to CLEM and fluorescence microscopy to assist in endocytic sorting in the School of Biochemistry at the University of Bristol.
Dr Paul Verkade is a Reader in Cell Imaging in the School of Biochemistry at the University of Bristol where he also heads the Electron Microscopy unit of the Wolfson Bioimaging Facility. His current research focus is to develop techniques and tools for the use of Correlative Light Electron Microscopy (CLEM) studying endocytic sorting. Dr. Verkade is currently chair of the Electron Microscopy section of the Royal Microscopy Society and chair of...
The Clinical and Laboratory Standards Institute (CLSI) has published a revised document titled Methods for Antimicrobial Dilution and Disk Susceptibility Testing of Infrequently Isolated or Fastidious Bacteria (M45-Ed3).
This guideline informs clinical, public health, and research laboratories on susceptibility testing of infrequently isolated or fastidious bacteria that are not included in CLSI documents M02, M07, or M100. Antimicrobial agent selection, test interpretation, and quality control are discussed. Susceptibility testing is particularly necessary in situations in which the etiological agent belongs to a bacterial species for which resistance to commonly used antimicrobial agents has been documented...
Titan Enterprises has published the latest issue of fLowdown, a newsletter that provides scientists and engineers with flow measurement technical tips and a review of the technological developments, applications advances and breaking news in this field.
Drawing upon over 40 years experience of fluid handling technology and applications, the popular Trevor's technical tips column discusses the 10 most common mistakes people make when specifying a flowmeter. The flow technology spotlight in this new issue falls on differential flow meters. The author of this feature provides an unbiased view of the technique benefits, shortfalls and the applications to which differential flow meters are best suited. Flowmeter performance critically depends...
Collaboration aims to reduce the complexity, costs and time involved in CRISPR/Cas9 gene editing
Desktop Genetics Ltd a software company revolutionizing the way biologists use CRISPR/Cas9 gene editing technology, announced today that it has signed a partnership agreement with Transcriptic Inc, a California based robotic cloud laboratory for life sciences. The partnership, announced at the SynBioBeta conference, will combine DTG’s CRISPR/Cas9 design software with Transcriptic’s services for cloud-based, high throughput cloning of CRISPR constructs, which will enable to companies to provide customers with seamless “CRISPR gene editing on-demand”...
Mazurek Optical Services are pleased to announce they have recently installed a suite of light microscopes in the School of Earth and Ocean Sciences at Cardiff University.
The microscopes have already been used in the undergraduate teaching laboratories by students returning for the new academic year. The School of Earth and Ocean Sciences at Cardiff University offers students a research-led experience across a wide raft of disciplines. They provide undergraduates with top class facilities that include dedicated IT labs, state-of-the-art analytical equipment and even their own research vessel. To coincide...
INSPIRE consortium receives UK MHRA approval for study
The INSPIRE consortium, led by Videregen Ltd, has received approval from the MHRA to start a UK clinical trial with its tissue engineered replacement trachea. The trial, which is expected to start in the first half of 2016, will focus on severe structural airway disease (SSAD), a potentially life-threatening condition believed to affect 19,000 people in Europe and the US. Along with Videregen as commercial partner, the consortium includes...
Beckman Coulter Diagnostics has today made available Issue 4 of its DxN VERIS Molecular Diagnostics Evidence Pack.
Following presentation of eight new scientific posters at the European Society for Clinical Virology meeting in Edinburgh, Scotland (September 2015), the Evidence Pack has been updated and now contains more than 20 evaluation posters presented at key infectious disease meetings across Europe. “These independent evaluations of our DxN VERIS Molecular Diagnostics System and assays* will be of great interest to virology laboratories...
Deben, a leading provider of in-situ testing stages together with innovative accessories and components for electron microscopy, reports on the use of the Microtest 200 N tensile stage in the Department of Aeronautics at Imperial College.
London where it is used to measure load displacement curves on nanocellulose-reinforced polymer composites. Dr Koon-Yang Lee is a Lecturer in Composite Manufacturing in the Department of Aeronautics at Imperial College London. His young and dynamic research group focuses on the manufacturing of polymer (nano)composites, surface and interface engineering, particle stabilised emulsions and foams. His research is highly...
Top 20 pharma and top 10 global CRO sign on as first Veeva Vault Study Start-Up customers
At the Veeva 2015 R&D Summit today, Veeva Systems announced the first fully integrated clinical trials study start-up solution. Veeva Vault Study Start-Up will enable life sciences organizations to manage both the content and the activities associated with activating sites for clinical trials. This comprehensive solution will accelerate time to first patient enrollment, automate manual processes, and deliver seamless interoperability with eTMF for a...
Haydale announces that it has received confirmation from the European Patent Office (EPO) of the decision to grant a European Patent for its proprietary HDPlas® functionalisation process for graphene and other nanoparticulate materials.
The European Patent is the key process patent underlying the Company's proprietary functionalisation treatment and is one of a number arising from the families of patent applications surrounding Haydale's unique plasma functionalisation process. Haydale already has a granted patent in China and has visibility on the patent application in Australia, which is expected to proceed to grant within the next 3-4 months. Crucially, the European...