Okadaic acid is diarrhetic toxin (DSP) which can be found in shellfish. Due to its inhibitory effects towards specific protein phosphatases it is a promising compound for various potential medical uses. This application note shows the LC-MS/MS analysis of okadaic acid and its derivates with different YMC-Triart phases. All phases are suitable for the separation of these compounds with high resolution....
Using HS antibodies from AMSBIO, researchers have demonstrated that Heparanase enzyme contributes to the pathogenesis of COVID-19, with both Heparanase activity and HS levels being elevated in plasma of Covid-19 patients. In addition, recent published data has shown that Heparanase activity is further elevated in ICU patients on ventilators compared to less serious cases....
Dr Sally Price, Head of Cell and Translational Science at Medicines Discovery Catapult (MDC) has been named in BioBeat’20 Movers & Shakers in BioBusiness 2020. Dr Price was instrumental in setting up the Alderley Park Lighthouse Lab, which forms part of the largest diagnostic testing facility in British history, to help in the fight against Coronavirus.
Porvair Sciences reports, due to promising results, it has agreed with its collaborative partners to make additional investment in the CEAT project which aims to dramatically improve the diagnosis and treatment of ovarian cancer. In the initial stage of the CEAT (Cluster for Epigenomic and Antibody Drug Conjugate Therapeutics) project - Porvair Sciences supplied its proprietary Chromatrap®....
Start Codon, a life science and healthcare business accelerator based in Cambridge, UK, has announced that it has closed Start Codon Fund I LP (the “Fund”) at £15 million. The Fund will be used to support Start Codon’s offering to start-ups, which includes a minimum of £250K seed funding, business support services, expert guidance, and access to cutting-edge office and lab facilities. Limited Partner ("LP") investors in the Fund include Novartis International AG and Cambridge Innovation Capital....
Pfizer and BioNTech SE have announced that they have reached an agreement with the European Commission to supply 200 million doses of their investigational BNT162b2 mRNA-based vaccine candidate against SARS-CoV-2 to European Union (EU) Member States, with an option for the European Commission to request an additional 100 million doses. Deliveries are anticipated to start by the end of 2020, subject to clinical success and regulatory authorization....
Label-free holotomography enables quantitative morphological and biophysical analysis of Atherosclerosis foam cells and precise measurement of targeted nanodrug effectiveness at single-cell level. Treatment of Atherosclerosis, the disease responsible for approximately half of all deaths in westernised societies, is a step closer following correlative studies using Tomocube’s HT-2 microscope....
In some methods derived from the Pharmacopoeia the stipulation of a specific injection solvent can lead to issues with peak shape and a reduced sensitivity for some or all compounds analysed. With a custom injection program, you can overcome this hurdle and still be conform to Pharmacopoeia guidelines. Your gain will be a higher chance to achieve your system suitability criterions and a more reproducible and robust analysis...
Autoscribe Informatics, a leading global laboratory informatics provider, announced the release of a new white paper examining the role of a Laboratory Information Management System (LIMS) in supporting ISO17025 accreditation. The white paper explores the ways in which a Laboratory Information Management System (LIMS) can play a key role in achieving, maintaining, and benefiting from ISO17025 accreditation...
Thermo Fisher Scientific, the world leader in serving science, and the Biopharmaceutical Analysis Training Laboratory (BATL) at Northeastern University, have entered into a collaborative agreement in a bid to advance analytical capabilities and drive innovation across the biopharmaceutical industry in areas including personalized medicine, monoclonal antibodies and gene and cell therapies....
Biotechnology education company Edvotek is dedicated to bringing high technology sciences to the classroom, helping future scientists to learn about the rapidly evolving biotechnology industry. The company uses INTEGRA Biosciences’ pipettes to produce training kits for teachers, helping them to share the latest exciting scientific developments with their students...
Specialty chemicals manufacturer FAR Chemical is using Matrix Gemini LIMS to improve the efficiency of its operations by significantly reducing the time taken to test and approve samples in the laboratory, the hold-times of products in the reactors have been cut and the efficiency of the entire operation improved. Based in Palm Bay, Florida, FAR Chemical is a leading manufacturer of complex specialty chemicals....
“Microplastics have invaded virtually every crevice on Earth” – a recent headline from a National Geographic article that highlights the global issue of the volume of microplastics in our environment. Microplastics are defined as small solid particles of less than 5 mm composed of polymers. Additionally, they may also contain additives, such as dyes, and impurities from manufacturing. They are either described as primary microplastics which are plastics intentionally made small (e.g. microbeads), or secondary microplastics...
Thermo Fisher Scientific, the world leader in serving science, and Symphogen, an affiliate of and the antibody center of excellence within the international pharmaceutical company, Servier, announce the extension of a strategic collaboration to deliver industry-proven, innovative characterization and quality control workflows for the simplified analysis of complex therapeutic proteins to advance biopharmaceutical discovery and development....
UNION therapeutics A/S (UNION) announces expansion of the clinical pipeline with the addition of UNI91103 (intranasal niclosamide) to prevent COVID-19 and reduce the severity of the diseases among those already infected. Several high-risk patient groups do not respond well to vaccination suggesting a persistent need for alternative prophylactic measures. In response, UNION has expanded its clinical program for COVID-19 with a niclosamide based nasal spray...
The Granupack is helping many industries to understand better their powder behavior! A new instrument is now available in the Granutools products, the Granupack High Temperature which does everything the Granupack does but also enable you to control the temperature of the cell with precision (up to 200°C). You will be surprised to discover how even slight changes in temperature can affect the flowing properties of your powders...
HCS Pharma is a biotech start-up focused on in vitro preclinical R&D. They specialize in phenotypic screening of physiologically relevant 3D cell models that also consider the extracellular matrix (ECM). See how the team save time and money with automated High-Content Screening (HCS) and imaging approaches, in collaboration with Molecular Devices…
INTEGRA Biosciences’ VIAFILL reagent dispenser is the perfect complement to magnetic particle processors such as ThermoFisher’s KingFisher™ system, streamlining workflows for extraction and purification of nucleic acids. The VIAFILL enables rapid reagent preparation for automated extraction, and supports optimized dispensing of various solutions, such as viscous wash buffers and beads, or volatile liquids like ethanol....
Evaxion Biotech A/S has received funding from the Danish Innovation Fund to further develop their AI platform RAVEN to rapidly respond against future corona virus pandemics - from initial discovery to first in human trials in as little as 13 weeks. During those 13 weeks SB3000 intends to develop and validate a tailored μLOT® continuous manufacturing process for the vaccine at commercial scale. Being modular and easily transportable the μLOT® enabled production units can be deployed to sites across the world....
As more lab personnel work from home to practice social distancing, employees are using remote work IT platforms to communicate and stay productive. But this change in the way scientists and lab personnel work means labs must adapt their methods to fully leverage remote platforms. If you’re not sure where to start, this blog can help. Here are six tips to help you successfully implement remote microscopy...
After encouraging results obtained under named patient use in severe cases of COVID-19, F4 Pharma is now preparing clinical trials in several European centers with its substance FX06. There is emerging evidence that severe COVID-19 affects all organs through a systemic inflammation of the inner layer of the small blood vessels leading to increased permeability of the capillaries, which can finally result in multi-organ failure and death...
Sonic Healthcare UK’s Group Medical Director, Dr Rachael Liebmann, and Ann Hannah, Rapid Response Laboratories and Histology Manager, have been recognised in the Queen’s Birthday Honours. Dr Liebmann has been awarded an OBE (Officer of the Most Excellent Order of the British Empire) in the Queen’s Birthday Honours in recognition of her services to pathology. Ann Hannah has been awarded a BEM (British Empire Medal) for her services to healthcare during the Covid-19 pandemic....
Okadaic acid is diarrhetic toxin (DSP) which can be found in shellfish. Due to its inhibitory effects towards specific protein phosphatases it is a promising compound for various potential medical uses. This application note shows the LC-MS/MS analysis of okadaic acid and its derivates with different YMC-Triart phases. All phases are suitable for the separation of these compounds with high resolution....
Using HS antibodies from AMSBIO, researchers have demonstrated that Heparanase enzyme contributes to the pathogenesis of COVID-19, with both Heparanase activity and HS levels being elevated in plasma of Covid-19 patients. In addition, recent published data has shown that Heparanase activity is further elevated in ICU patients on ventilators compared to less serious cases....
Dr Sally Price, Head of Cell and Translational Science at Medicines Discovery Catapult (MDC) has been named in BioBeat’20 Movers & Shakers in BioBusiness 2020. Dr Price was instrumental in setting up the Alderley Park Lighthouse Lab, which forms part of the largest diagnostic testing facility in British history, to help in the fight against Coronavirus.
Porvair Sciences reports, due to promising results, it has agreed with its collaborative partners to make additional investment in the CEAT project which aims to dramatically improve the diagnosis and treatment of ovarian cancer. In the initial stage of the CEAT (Cluster for Epigenomic and Antibody Drug Conjugate Therapeutics) project - Porvair Sciences supplied its proprietary Chromatrap®....
Start Codon, a life science and healthcare business accelerator based in Cambridge, UK, has announced that it has closed Start Codon Fund I LP (the “Fund”) at £15 million. The Fund will be used to support Start Codon’s offering to start-ups, which includes a minimum of £250K seed funding, business support services, expert guidance, and access to cutting-edge office and lab facilities. Limited Partner ("LP") investors in the Fund include Novartis International AG and Cambridge Innovation Capital....
Pfizer and BioNTech SE have announced that they have reached an agreement with the European Commission to supply 200 million doses of their investigational BNT162b2 mRNA-based vaccine candidate against SARS-CoV-2 to European Union (EU) Member States, with an option for the European Commission to request an additional 100 million doses. Deliveries are anticipated to start by the end of 2020, subject to clinical success and regulatory authorization....
Label-free holotomography enables quantitative morphological and biophysical analysis of Atherosclerosis foam cells and precise measurement of targeted nanodrug effectiveness at single-cell level. Treatment of Atherosclerosis, the disease responsible for approximately half of all deaths in westernised societies, is a step closer following correlative studies using Tomocube’s HT-2 microscope....
In some methods derived from the Pharmacopoeia the stipulation of a specific injection solvent can lead to issues with peak shape and a reduced sensitivity for some or all compounds analysed. With a custom injection program, you can overcome this hurdle and still be conform to Pharmacopoeia guidelines. Your gain will be a higher chance to achieve your system suitability criterions and a more reproducible and robust analysis...
Autoscribe Informatics, a leading global laboratory informatics provider, announced the release of a new white paper examining the role of a Laboratory Information Management System (LIMS) in supporting ISO17025 accreditation. The white paper explores the ways in which a Laboratory Information Management System (LIMS) can play a key role in achieving, maintaining, and benefiting from ISO17025 accreditation...
Thermo Fisher Scientific, the world leader in serving science, and the Biopharmaceutical Analysis Training Laboratory (BATL) at Northeastern University, have entered into a collaborative agreement in a bid to advance analytical capabilities and drive innovation across the biopharmaceutical industry in areas including personalized medicine, monoclonal antibodies and gene and cell therapies....
Biotechnology education company Edvotek is dedicated to bringing high technology sciences to the classroom, helping future scientists to learn about the rapidly evolving biotechnology industry. The company uses INTEGRA Biosciences’ pipettes to produce training kits for teachers, helping them to share the latest exciting scientific developments with their students...
Specialty chemicals manufacturer FAR Chemical is using Matrix Gemini LIMS to improve the efficiency of its operations by significantly reducing the time taken to test and approve samples in the laboratory, the hold-times of products in the reactors have been cut and the efficiency of the entire operation improved. Based in Palm Bay, Florida, FAR Chemical is a leading manufacturer of complex specialty chemicals....
“Microplastics have invaded virtually every crevice on Earth” – a recent headline from a National Geographic article that highlights the global issue of the volume of microplastics in our environment. Microplastics are defined as small solid particles of less than 5 mm composed of polymers. Additionally, they may also contain additives, such as dyes, and impurities from manufacturing. They are either described as primary microplastics which are plastics intentionally made small (e.g. microbeads), or secondary microplastics...
Thermo Fisher Scientific, the world leader in serving science, and Symphogen, an affiliate of and the antibody center of excellence within the international pharmaceutical company, Servier, announce the extension of a strategic collaboration to deliver industry-proven, innovative characterization and quality control workflows for the simplified analysis of complex therapeutic proteins to advance biopharmaceutical discovery and development....
UNION therapeutics A/S (UNION) announces expansion of the clinical pipeline with the addition of UNI91103 (intranasal niclosamide) to prevent COVID-19 and reduce the severity of the diseases among those already infected. Several high-risk patient groups do not respond well to vaccination suggesting a persistent need for alternative prophylactic measures. In response, UNION has expanded its clinical program for COVID-19 with a niclosamide based nasal spray...
The Granupack is helping many industries to understand better their powder behavior! A new instrument is now available in the Granutools products, the Granupack High Temperature which does everything the Granupack does but also enable you to control the temperature of the cell with precision (up to 200°C). You will be surprised to discover how even slight changes in temperature can affect the flowing properties of your powders...
HCS Pharma is a biotech start-up focused on in vitro preclinical R&D. They specialize in phenotypic screening of physiologically relevant 3D cell models that also consider the extracellular matrix (ECM). See how the team save time and money with automated High-Content Screening (HCS) and imaging approaches, in collaboration with Molecular Devices…
INTEGRA Biosciences’ VIAFILL reagent dispenser is the perfect complement to magnetic particle processors such as ThermoFisher’s KingFisher™ system, streamlining workflows for extraction and purification of nucleic acids. The VIAFILL enables rapid reagent preparation for automated extraction, and supports optimized dispensing of various solutions, such as viscous wash buffers and beads, or volatile liquids like ethanol....
Evaxion Biotech A/S has received funding from the Danish Innovation Fund to further develop their AI platform RAVEN to rapidly respond against future corona virus pandemics - from initial discovery to first in human trials in as little as 13 weeks. During those 13 weeks SB3000 intends to develop and validate a tailored μLOT® continuous manufacturing process for the vaccine at commercial scale. Being modular and easily transportable the μLOT® enabled production units can be deployed to sites across the world....
As more lab personnel work from home to practice social distancing, employees are using remote work IT platforms to communicate and stay productive. But this change in the way scientists and lab personnel work means labs must adapt their methods to fully leverage remote platforms. If you’re not sure where to start, this blog can help. Here are six tips to help you successfully implement remote microscopy...
After encouraging results obtained under named patient use in severe cases of COVID-19, F4 Pharma is now preparing clinical trials in several European centers with its substance FX06. There is emerging evidence that severe COVID-19 affects all organs through a systemic inflammation of the inner layer of the small blood vessels leading to increased permeability of the capillaries, which can finally result in multi-organ failure and death...
Sonic Healthcare UK’s Group Medical Director, Dr Rachael Liebmann, and Ann Hannah, Rapid Response Laboratories and Histology Manager, have been recognised in the Queen’s Birthday Honours. Dr Liebmann has been awarded an OBE (Officer of the Most Excellent Order of the British Empire) in the Queen’s Birthday Honours in recognition of her services to pathology. Ann Hannah has been awarded a BEM (British Empire Medal) for her services to healthcare during the Covid-19 pandemic....