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All articles from BioChromato Inc.

  Identification & Discrimination of Contamination from Food Wrap Plastics

BioChromato report how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART®-MS) provides a powerful new method capable of identifying and discriminating between different sources of plastic films used for food processing and packaging. Food wrap film, also known as cling film or plastic wrap, is widely used for food processing and packaging, leading to the risk that plastic might be introduced as a foreign matter into food items...

 

  Smart Evaporation Technology Increases Lab Efficiency

Solvent evaporation specialists - BioChromato Inc. has published an informative web page that describes how Vacuum Vortex Concentration (VVC) methodology enables users of its Smart Series of Evaporators remove even higher boiling solvents including water, DMSO and DMF quickly and safely. At the heart of each BioChromato Smart Evaporator is a highly efficient spiral airflow created by a special concentrator plug or “Spiral Plug”....

 

  Optimized Tube Plate for Enzyme Studies

BioChromato Inc. has developed an enzyme assay product - the RAPID Tube Plate 600 (TP-600) that is helping deliver outstanding results in in vitro metabolic stability studies. The TP-600 is manufactured from ultra-pure polypropylene that does not contain any enzyme inhibitors such as EDTA or other contaminants that may degrade your assay results. In addition, the TP-600 is guaranteed to be Human DNA, DNase and RNase free....

 

  Mass Spectrometry Structural Analysis of Fluoroelastomers

BioChromato Inc. has published a report describing how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART-MS) and Kendrick Mass Defect (KMD) analysis, provides a valuable new tool for chain analysis of fluoroelastomers. Because of their excellent heat, chemical and abrasion resistance - fluoropolymers are widely used in automotive parts and many other industrial products....

 

  Parallel Evaporator Assists Metabolomics Research

BioChromato Inc. has published an interview with the Institute of Analytical Sciences, Faculty of Pharmaceutical Sciences at the University of Fukuoka (Fukuoka, Japan) that explains how a Smart Evaporator C10 has enabled them to concentrate amino acids, without denaturation, such that they can be detected by LC/MS/MS. Researchers at the Institute of Analytical Sciences conducting fundamental metabolomics research on the state of cultured cells, wished to measure amino acids produced in their cell culture medium....

 

  Rapid, Direct Mass Spectrometry Characterisation of Difficult Samples

The ionRocket from BioChromato Inc. is a temperature-heating device for direct thermal desorption and pyrolysis of samples, prior to ionization and analysis by mass spectrometry. Direct Analysis in Real Time Mass Spectrometry (DART-MS) is a proven technique that enables rapid analysis of both solid and liquid samples under standard laboratory conditions without sample preparation....

 

  Contamination-free Microplate Sealing for ADME Screening

BioChromato Inc. reports on how Pharmaceutical companies undertaking Absorption, Distribution, Metabolism and Excretion (ADME) studies are benefiting from integrating RAPID Easy Piercing Seals (EPS) into their screening protocols. Optimization of the ADME properties of a drug molecule is one of the most difficult and challenging part of the drug discovery process. The ADME profile of a compound has a major impact on the likelihood of its success as a drug....

 

  Smart Evaporator Assists Medicinal Chemistry

BioChromato Inc. has published an interview with the Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University (Indiana, USA) that explains how the Smart Evaporator C1 has assisted them in isolating and purifying novel compounds from DMSO solutions for potential pharmaceutical use. Because the US Federal Drug Administration (FDA) does not approve DMSO formulations for human administration, researchers at Purdue University wanted to synthesise a new Platinum (IV) chloride complex...

 

  High Integrity Microplate Sealing for LC/MS Applications

RAPID EPS seals from BioChromato Inc. are designed for scientists looking to prevent contamination issues and autosampler needle clogging when accessing samples stored in 96-well microplates ready for LC/MS analysis. For LC/MS users, a key criterion for an effective microplate seal is its resistance to solvents such as Acetonitrile, Methanol and DMSO which are commonly used in experiments and analysis....

 

  Personal Benchtop Evaporator for DMSO & DMF Samples

BioChromato Inc. reports on installation of over 1200 units of its Smart Evaporator C1 - a compact system that delivers rapid concentration or complete drying of samples in even high boiling solvents such as DMSO, DMF or water. Designed to be easy to use - the Smart Evaporator C1 is an affordably priced system optimised to concentrate or dry single samples directly from any tube or vial (up to 32mm neck diameter)....

 

  Sterile 96-Well Plate Seal for Cell Culturing

BioChromato Inc. has introduced a gamma sterilized version of its popular RAPID Slit Seal for scientists looking to eliminate solvent evaporation from samples when culturing cells in 96-well microplates. Proven in labs worldwide, RAPID Slit Seal is a proprietary self-closing microplate seal that returns to its original state even when punched with an HPLC or LC/MS autosampler....

 

 

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