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All articles from BioChromato Inc.

  Rapid concentration of high boiling point samples

Designed to be easy to use - the Smart Evaporator C1 from  BioChromato Inc. Is a compact, affordably priced system that delivers rapid concentration or complete drying of samples from high boiling solvents including DMSO, DMF and water. Drawing upon BioChromato’s patented spiral plug evaporation technology, the compact, benchtop Smart Evaporator C1 offers fast and effective evaporation directly from tubes or vials without solvent bumping thereby eliminating risk of sample loss, cross contamination and saving researchers time....

 

  Mass Spectrometry method reveals thermal history of recycled polymers

BioChromato Inc. has demonstrated how a Thermal Desorption and Pyrolysis / Direct Analysis in Real Time-Mass Spectrometry (TDP/DART-MS) analysis method can reveal the thermal history of recycled thermoplastic resins. Recycling thermoplastic resins such as polypropylene is regarded as a vital step to help realise a more sustainable society. However, physical properties of thermoplastic resins such as strength and ability to elongate are known to degrade after repeated thermal reprocessing....

 

  Microplate seal facilitates high precision repeat analysis

BioChromato reports how its RAPID Slit Seal microplate seals are helping labs to maintain the integrity of reconstituted samples over several days thereby enabling high precision repeat analysis. Used in pharmaceutical, biotech and healthcare labs worldwide, RAPID Slit Seal is a unique self-closing 96-well microplate seal that returns to its original state even when punched with a HPLC or LC/MS autosampler...

 

  Evaporator Improves Concentration of Aqueous Pharmaceutical Samples

BioChromato has published an interview with the Department of Biomedical Pharmaceutics at Gifu Pharmaceutical University in Japan that describes how its Smart Evaporator C1 fitted with 4-Kit has revolutionised its aqueous sample preparation. The Department of Biomedical Pharmaceutics, headed by Professor Kiyoyuki Kitaichi, is well known for its pioneering collaborative research on illegal drugs, pharmaceuticals, and new health food ingredients....

 

  Comparison of Mass Spectrometry Sample Preparation Methods

BioChromato has published a technical note that compares using Evolved Gas Analysis (EGA) and Thermal Desorption (DART) sample preparation methods for Mass Spectrometry analysis of Nylon 6,6. Synthesized by polycondensation of hexamethylenediamine and adipic acid – Nylon 6,6 is a polyamide or nylon that is commonly used in the textile and plastic industries. Nylon 6,6 is a polymer of choice when high mechanical strength, rigidity, good stability under heat and/or chemical resistance are required....

 

  Evaporators Assist Academic Drug Discovery

BioChromato Inc reports how the renowned Chemistry Research Laboratories (CRL) at Oxford University (UK) are using several Smart Evaporator C1 units to support their drug discovery activities in therapeutic areas including oncology and regenerative medicine. The Smart Evaporator C1 units, ably supported by local agent – Asynt, have found wide ranging use by the medicinal chemistry team....

 

  Routine DART®-MS analysis of low solubility, high molecular weight compounds

BioChromato Inc. reports how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART®-MS), enables routine analysis of low solubility, high molecular weight compounds. Phthalocyanine based pigments are widely used for organic semiconductors and organic electroluminescence displays due to their clearness, high light stability, and durability. However, the chemical structure of Phthalocyanine based pigments are difficult to analyze...

 

  Fast & Effective Evaporator Improves Bioremediation Sample Preparation

BioChromato Inc. has published an interview that describes a new bioremediation technique developed by a leading Environmental Research Center and how the Smart Evaporator C1 offers a productive tool for preparing microbial degradation culture media for analysis. The novel bioremediation technique, based upon patented degrading microorganisms impregnated on carbonized wood, has been demonstrated to detoxify persistent organic pollutants (POPs) that cannot be decomposed by natural processes in soil.

 

  Russian Institutes Invest in BioChromato Smart Evaporators

BioChromato reports that it has installed more than 10 Smart Evaporator systems across the Russian Hygiene and Epidemiology Centers (HEC) network of institutes as part of a national program of acquiring leading edge analytical and sample preparation equipment. This major investment by the Hygiene and Epidemiology Centers was to enable them to improve the well-being of the population by monitoring...

 

  Identification & Discrimination of Contamination from Food Wrap Plastics

BioChromato report how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART®-MS) provides a powerful new method capable of identifying and discriminating between different sources of plastic films used for food processing and packaging. Food wrap film, also known as cling film or plastic wrap, is widely used for food processing and packaging, leading to the risk that plastic might be introduced as a foreign matter into food items...

 

  Smart Evaporation Technology Increases Lab Efficiency

Solvent evaporation specialists - BioChromato Inc. has published an informative web page that describes how Vacuum Vortex Concentration (VVC) methodology enables users of its Smart Series of Evaporators remove even higher boiling solvents including water, DMSO and DMF quickly and safely. At the heart of each BioChromato Smart Evaporator is a highly efficient spiral airflow created by a special concentrator plug or “Spiral Plug”....

 

  Optimized Tube Plate for Enzyme Studies

BioChromato Inc. has developed an enzyme assay product - the RAPID Tube Plate 600 (TP-600) that is helping deliver outstanding results in in vitro metabolic stability studies. The TP-600 is manufactured from ultra-pure polypropylene that does not contain any enzyme inhibitors such as EDTA or other contaminants that may degrade your assay results. In addition, the TP-600 is guaranteed to be Human DNA, DNase and RNase free....

 

  Mass Spectrometry Structural Analysis of Fluoroelastomers

BioChromato Inc. has published a report describing how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART-MS) and Kendrick Mass Defect (KMD) analysis, provides a valuable new tool for chain analysis of fluoroelastomers. Because of their excellent heat, chemical and abrasion resistance - fluoropolymers are widely used in automotive parts and many other industrial products....

 

  Parallel Evaporator Assists Metabolomics Research

BioChromato Inc. has published an interview with the Institute of Analytical Sciences, Faculty of Pharmaceutical Sciences at the University of Fukuoka (Fukuoka, Japan) that explains how a Smart Evaporator C10 has enabled them to concentrate amino acids, without denaturation, such that they can be detected by LC/MS/MS. Researchers at the Institute of Analytical Sciences conducting fundamental metabolomics research on the state of cultured cells, wished to measure amino acids produced in their cell culture medium....

 

  Rapid, Direct Mass Spectrometry Characterisation of Difficult Samples

The ionRocket from BioChromato Inc. is a temperature-heating device for direct thermal desorption and pyrolysis of samples, prior to ionization and analysis by mass spectrometry. Direct Analysis in Real Time Mass Spectrometry (DART-MS) is a proven technique that enables rapid analysis of both solid and liquid samples under standard laboratory conditions without sample preparation....

 

  Contamination-free Microplate Sealing for ADME Screening

BioChromato Inc. reports on how Pharmaceutical companies undertaking Absorption, Distribution, Metabolism and Excretion (ADME) studies are benefiting from integrating RAPID Easy Piercing Seals (EPS) into their screening protocols. Optimization of the ADME properties of a drug molecule is one of the most difficult and challenging part of the drug discovery process. The ADME profile of a compound has a major impact on the likelihood of its success as a drug....

 

  Smart Evaporator Assists Medicinal Chemistry

BioChromato Inc. has published an interview with the Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University (Indiana, USA) that explains how the Smart Evaporator C1 has assisted them in isolating and purifying novel compounds from DMSO solutions for potential pharmaceutical use. Because the US Federal Drug Administration (FDA) does not approve DMSO formulations for human administration, researchers at Purdue University wanted to synthesise a new Platinum (IV) chloride complex...

 

  High Integrity Microplate Sealing for LC/MS Applications

RAPID EPS seals from BioChromato Inc. are designed for scientists looking to prevent contamination issues and autosampler needle clogging when accessing samples stored in 96-well microplates ready for LC/MS analysis. For LC/MS users, a key criterion for an effective microplate seal is its resistance to solvents such as Acetonitrile, Methanol and DMSO which are commonly used in experiments and analysis....

 

  Personal Benchtop Evaporator for DMSO & DMF Samples

BioChromato Inc. reports on installation of over 1200 units of its Smart Evaporator C1 - a compact system that delivers rapid concentration or complete drying of samples in even high boiling solvents such as DMSO, DMF or water. Designed to be easy to use - the Smart Evaporator C1 is an affordably priced system optimised to concentrate or dry single samples directly from any tube or vial (up to 32mm neck diameter)....

 

  Sterile 96-Well Plate Seal for Cell Culturing

BioChromato Inc. has introduced a gamma sterilized version of its popular RAPID Slit Seal for scientists looking to eliminate solvent evaporation from samples when culturing cells in 96-well microplates. Proven in labs worldwide, RAPID Slit Seal is a proprietary self-closing microplate seal that returns to its original state even when punched with an HPLC or LC/MS autosampler....

 

 

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