SP Scientific, and Praxair Inc., headquartered in Danbury, CT, are pleased to announce the expansion of their collaborative relationship to commercialize Praxair's ControLyo^TM Nucleation on Demand Technology.

The original agreement, signed in October 2010, gave SP Scientific the exclusive, global rights to commercialize the technology on Development Lyophilizers <1.0 m. The Praxair ControLyo^TM Technology was implemented on SP Scientific's Lyostar 3 Freeze Dryer in December 2010. The expansion of the agreement allows SP Scientific to also equip its clinical, pilot and production dryers (Benchmark series and Hull Production Dryers) with the ControLyo^TM Technology. Additionally, the agreement calls for the transfer of technology to allow SP Scientific to retrofit existing Pilot and Production units in the field, regardless of the original manufacturer.

"This is a major step in SP's strategy of technology leadership in lyophilization," states Chuck Grant, CEO for SP Scientific. "Given the ability to offer the technology from development through scale-up to production, SP Scientific is ideally positioned to be the supplier of choice for ControLyo^TM Technology."

"Praxair is pleased to extend our existing agreement to cover the full range of lyophilizers offered to the industry by SP Scientific, " said Rich Jarrett, Global Director of Marketing and Business Development for Praxair. "Praxair's ControLyo^TM Technology has seen quick industry adoption with SP Scientific's Lyostar 3 FreezeDryer and we look forward to providing the industry with nucleation control at all production levels."

ControLyo^TM Technology offers many benefits to the pharmaceutical industry including: vial-to-vial uniformity, reduced cycle times, reduced protein aggregation and better conformance to the Food and Drug Administration's Process Analytical Technology (PAT) initiative.

SP Scientific is a leading manufacturer of laboratory-to-production scale freeze dryers / lyophilizers, centrifugal evaporators and concentrators, thermal management system and glassware washers. The company sells its products under well-known brands including Hull, VirTis®, FTS Systems^TM, Genevac®, and National-Hotpack®. SP Scientific has ISO 9001:2008 registered production facilities in the USA and Europe.

Praxair Inc. is the largest industrial gases company in North and South America, and one of the largest worldwide, with 2011 sales of $11 billion. The company produces, sells and distributes atmospheric, process and specialty gases, and high-performance surface coatings. Praxair products, services and technologies are making our planet more productive by bringing efficiency and environmental benefits to a wide variety of industries, including aerospace, chemicals, food and beverage, electronics, energy, healthcare, manufacturing, metals and others.