Channels

 

Special Offers & Promotions

 

 

Latest News

 

 

View Channel

New Products

 

 

View Channel

Video Presentations

 

 

View Channel

Separation Science

 

 

View Channel

Microscopy & Image Analysis

 

 

View Channel

Laboratory Automation & IT Solutions

 

 

View Channel

 

Affordable Large-Scale DNA Variation Studies for Every DNA Researcher

publication date: Oct 15, 2015
 | 
author/source: GENALICE

GENALICE has announced the global launch date of Population Calling, a new analysis module and part of their GENALICE MAP Next-Generation Sequencing (NGS) Data Analysis Suite.

GenaliceIn a LIVE webinar event scheduled in two weeks from today, on October 8, the company will reveal the unique capabilities to improve individual patient results and discover disease specific DNA changes at significantly reduced cost and time to result.
 
Hans Karten, CEO/CTO of GENALICE explains: “Single sample variant detection is the standard approach to determine DNA changes in an individual patient that may be related to disease. Population Calling, also referred to as ‘Joint Calling’ or ‘Pooled Calling’ by others, is an improved NGS data analysis methodology in which multiple samples from a cohort study are examined in a single variant detection analysis. The aggregate information of all samples is used to improve the sensitivity and precision to detect all DNA changes in a single sample. This means that individual patient’s diagnosis is enhanced using the consensus result of an entire cohort. Population Calling provides a strong context for new biomarker discoveries in research and high confidence diagnosis in clinical application.
 
Nationwide studies, like the last week announced U.S. National Institutes of Health (NIH) framework, in which a cohort of one million or more Americans is studied, aim to expand the knowledge and practice of precision medicine. In phase III clinical drug development studies, cohort sizes range from 400 to 800 patients. And larger scale cohort studies easily include 5,000 to 10,000 patient samples.
 
In these and many other cases, Population Calling is considered of high importance, but it also creates a true big data challenge. As a result, to date, Population Calling using existing analysis tools, has been the preserved territory of a select group of large institutes and companies that have extensive knowledge, resources, budget and patience to wait for results.

Jos Lunenberg, GENALICE’ Chief Business Officer, comments: “It is time to make Population Calling available to every single genomics researcher at an unprecedented price point and analysis speed. We are collaborating with the expert teams from deCODE genetics and Mount Sinai Hospital (NYC). In two weeks we will remove the covers in a LIVE online event. We have chosen this date, as it coincides with the American Society of Human Genetics (ASHG) 2015 Annual Meeting in Baltimore (MA, USA), where thousands of genetics researchers are gathering and our team is present with a booth.

Lunenberg continues: “We have an incredible opportunity to advance research and make new medical breakthroughs through improved diagnosis and precision medicine, which tailors disease prevention and treatment to individuals driven by the analysis of their molecular profiles. GENALICE is proud to contribute to this important endeavor.”

About GENALICE

GENALICE is a highly innovative biomedical big data solutions company, with global headquarters in the Netherlands. GENALICE designs and builds groundbreaking software solutions for ultra-fast, highly accurate and cost-effective DNA data processing and analysis. The software is deployed on general-purpose hardware or flexible cloud. With GENALICE MAP, the company has introduced the first Next-Generation Sequencing (NGS) data processing pipeline with true population power. By partnering with world-renowned research institutes and healthcare companies, GENALICE is committed to unlocking the potential of whole genome, exome and transcriptome sequencing for biomarker discovery and clinical application.


more about genalice


 

 



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

 

Today's Picks

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners

 

Exhibitions & Events