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Automating the development of aptamer-based biological tools with Tecan
The ARNA Laboratory in Bordeaux, France, is using DNA and RNA aptamers to develop novel tools for biological applications.
To increase throughput, the laboratory has automated its procedures on two Freedom EVO® platforms, as Inserm Research Director Dr Jean-Jacques Toulmé explained: “Our association with Tecan began when we decided to automate our selection protocols to allow us to screen large libraries of oligonucleotides. We generally perform two selections in parallel, consisting of between 8 and 15 runs. With each run taking around six hours, the selection process is completed in about a week to 10 days. This would be difficult to do manually, and is a tedious, repetitive task for a scientist to carry out. We contacted various suppliers before choosing Tecan, investing in a Freedom EVO platform which enabled the process to be almost completely automated, freeing up staff time and helping us to achieve the desired throughput.”
“We then realized that we needed a second automated platform for our production processes, and chose a Freedom EVO with an integrated Infinite® M1000 PRO multimode reader. This gave us the capability to use additional techniques – including AlphaScreen® assays and fluorescence anisotropy – and everything is still working very smoothly. Automation has been a great benefit to our workflow.”
Find out more about Tecan’s protein purification and characterization solutions
For more information please contact
Tecan Trading AG
Antonietta Allocca
Seestrasse 103, CH-8708 Männedorf
Tel +41 (0)44 922 81 11, Fax +41 (0)44 922 81 12
info@tecan.com www.tecan.com
About Tecan
Tecan (www.tecan.com) is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics and clinical diagnostics. The company specializes in the development, production and distribution of automated workflow solutions for laboratories in the life sciences sector. Its clients include pharmaceutical and biotechnology companies, university research departments, and forensic and diagnostic laboratories. As an original equipment manufacturer (OEM), Tecan is also a leader in developing and manufacturing OEM instruments and components that are then distributed by partner companies. Founded in Switzerland in 1980, the company has manufacturing, research and development sites in both Europe and North America and maintains a sales and service network in 52 countries. In 2014, Tecan generated sales of CHF 400 million (USD 437 million; EUR 331 million). Registered shares of Tecan Group are traded on the SIX Swiss Exchange (TECN; ISIN CH0012100191).
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