Particle size is a critical parameter
for inhaled drugs, with a defining influence on deposition behavior in the
lung. Particle characterization specialists Joe Wolfgang and Julie Chen from
Malvern Instruments will be on hand to discuss these issues at the Respiratory
Drug Delivery conference (RDD 2012) in Phoenix, Arizona, May 13-17, where
Malvern will showcase the recently launched
Mastersizer 3000 particle size analyzer.
The Mastersizer 3000 is a new, small
footprint laser diffraction particle
size analyzer. It has the widest measurement range on the market so
laboratories can use a single instrument to measure wet or dry dispersions from
10 nm to 3.5 mm without needing to change the optical setup. Major
technological advances in the new dry powder disperser allow this
environmentally friendly, convenient dispersion method to be used for an
extended range of materials, including fragile particles. Simple, intuitive
software guides both expert and novice users, with in-built intelligence and
streamlined workflows making good particle size measurements available to all.
Laser diffraction particle size
analyzers are proven and widely used within the pharmaceutical industry.
Increasingly, systems such as Malvern's Morphologi
G3, which measures the size and shape of particles using the technique of
static image analysis, are used in conjunction with laser diffraction to gain
a deeper understanding of product or process behavior. Having a more comprehensive
representation of particle size and shape can be important, especially when
trying to influence the way in which powders flow and disperse.
Where additional chemical
identification is needed - to distinguish actives within a formulation for
example - the Morphologi G3-ID integrates
automated size and shape analysis of particles from 0.5 micron to 1 mm with
chemical identification provided by Raman spectroscopy.
For information about the conference
please
click here or to find out more about Malvern's Mastersizer 3000 visit
www.malvern.com/MS3000
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