publication date: Jun 7, 2012
|
author/source: Definiens
Definiens
Tissue Studio Now Supports the Detection of Spot-like Signals from In Situ
Hybridization AssaysDefiniens
®, the leading
provider of image analysis and data mining solutions for quantitative digital
pathology, today announced that Definiens Tissue Studio
® 3.5 now
supports the automated analysis of in situ hybridization assays, including
SISH, CISH, FISH and dual-ISH. The unique combination of flexibility and
ease-of-use that characterizes Definiens Tissue Studio
®
significantly facilitates the detection of spot-like signals originating from
gene probes (or any other stain with spot-like appearance) on a cell-by-cell
basis. Definiens Tissue Studio
® supports the detection of gene probe
signals in both brightfield and immunofluorescene imaging.
The novel functionality complements the
robust detection of regions of interest and the comprehensive quantification of
cellular parameters and biomarker expression profiles. Definiens Tissue Studio
®
can be used to analyze images from any solid tissue with any stain, acquired by
any scanner or microscope, and in any common file format. With these
technological advances, pathologists and researchers can adapt preconfigured
solutions to their specific assays with just a few clicks in no more than 30
minutes.
Straightforward workflow, intuitive
configuration, as well as flexibility and robustness, have established
Definiens Tissue Studio as the leading image analysis solution for quantitative
digital pathology. Definiens Tissue Studio opens new dimensions in
quantification by significantly reducing study times in translational research,
preclinical safety, tissue-based biomarker development and clinical trials
around the world. The new version includes a range of improvements that make it
easier to use and more powerful than ever.
"Definiens has developed significant
experience in the analysis of in situ hybridization assays in recent years,"
said Thomas Heydler, CEO of Definiens. "In Definiens Tissue Studio
®
3.5, we now make this available to our customers in a very easy-to-use workflow
that supports virtually any type of 2D ISH assay. This further strengthens
Definiens Tissue Studio's position as the most comprehensive software package
for quantitative digital pathology."
With just a single configuration, Definiens
Tissue Studio
® automates the detection of regions of interest and
has the capacity to distinguish individual cells and subcellular structures
even in heterogeneous tissues samples. The software provides quantitative
readouts on morphological characteristics and molecular expression profiles of
nuclear, cytoplasmic and membrane biomarkers. In addition, Definiens Tissue Studio
®
supports robust detection of vessels for automated angiogenesis assays as well
as extensive multiplexing for the quantification of numerous parameters from
the same tissue sample in immunofluorescence assays.
Visit
tissuestudio.definiens.com
to learn more or watch the recordings of an introductory webinar series on
Definiens' YouTube
channel
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