BUCHI's latest products - the Encapsulator B-390 and B-395 Pro - are new
systems for the immobilization of enzymes, drugs, flavours & fragrances,
vitamins, oils, cells or microbes into
a wide range of polymers, such as alginate, carrageen, cellulose
sulphate, chitosan, gelatine or pectin, as well as waxes. Uniform capsules and beads are produced
with the same technology. Their size is
pre-selectable in the range of 0.15
mm to 2 mm with a spherical shape and narrow size distribution (< 5%
standard deviation) and a productivity of up to 6'000 beads per second.
The Encapsulator B-390 and B-395 Pro use the same unique technology,
which is based on the principle that a laminar flowing liquid jet breaks up
into equally sized droplets by superimposed vibration. The selectable vibration
frequency determines the quantity of droplets produced; for example, 1'000
droplets are generated per second at 1'000 Hz. The droplet chain is
electrostatically charged causing the droplets to repel each other, thus
eliminating coalescence. The droplets fall into a hardening solution where the
beads are polymerized quickly or in a cooling chamber where the beads solidify.
The clever bench-top design and innovative technology make the Encapsulator
B-390 and B-395 Pro especially suitable for the evaluation of encapsulation
during the early stages of product development to perform feasibility studies
in R&D laboratories and academical research, such as:
Pharmaceutical
Industry-
Encapsulation of active ingredients (e.g. poorly
soluble drugs in polymeric microspheres)
- Drug delivery systems with controlled drug release (e.
g. biodegradable polylactic-acid beads)
- Protection of active ingredients (e.g. reducing
interaction with other agents during storage)
- Coating of particles with new functions (e.g.
modulated release)
- Taste masking of bitter agents in capsules produced
with concentric nozzles
- Encapsulation of vaccines for wild animals
- Sterile encapsulation of mammalian cells and thereby
protection of cells from the immune system for cell transplantation (e.g.
treatment of gene deficiency)
- Protection of cells from shear stress in stirred
reactors
- Capsules as micro systems for cell retention with high
cell density
- Immobilization of
microbes and enzymes for biotransformation
Food Industry-
Encapsulation of probiotic ingredients (e.g. lactic
acid bacteria)
- Stabilization and protection of neutraceuticals (e.g.
vitamins, oils)
- Optical enhancement of foodstuff
- Molecular kitchen
applications
Benefit from the continuous and mild capsule generation, reproducibility
and user friendliness. Installation is fast and simple; operation is learned
quickly and is easy.
Visit our homepage at www.buchi.com
and be inspired by the wide variety of applications ranging from controlled release and protection systems,
coatings with functional groups, immobilization studies, or improvement tests of stability, dosage and
storage.
If you would like to get more information about BUCHI's Encapsulator products, please
contact: Dr. Raphael Plüss, Tel. +41 71
394 63 73 or send an e-mail to
pluess.r@buchi.com
or go to
www.buchi.com
Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!
Request your free copies HERE
Popular this Month
Top 10 most popular articles this month
Today's Picks
Looking for a Supplier?
Search by company or by product
Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.
Lab Bulletin is published by newleaf marketing communications ltd.