Recently AMSBIO introduced US Food & Drug Administration (FDA) standard TMAs for human, mouse and rat to its portfolio. Designed in close conformance with FDA guidelines, this range meets the requirements for tissue cross-reactivity studies required for therapeutic and diagnostic antibody and antibody-like molecules validation. Each array slide features the FDA recommended list of normal tissue types in triplicate, allowing the identification of off-target binding and on-target binding that has not been previously identified.
Tissue microarray slides offer a rapid and cost-effective direct method for the validation of biological targets in multiple tissue samples. Parallel analysis of multiple specimens reduces operating times, conserves reagents and facilitates high-throughput molecular analysis of tissues.
The new FDA standard TMAs form part of AMSBIO’s broad collection of normal and tumor TMAs available in FFPE and frozen formats. Produced using high-quality tissue samples selected by board-certified pathologists, TMAs are a remarkable tool with a range of potential applications in basic research, prognostic oncology and drug discovery.