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Thermo Fisher Scientific has released a new 58-page compendium for its solid-core HPLC columns (Thermo Scientific^TM Accucore^TM HPLC columns) titled, Solid Core Technical Compendium.

These solid-core HPLC columns use our Core Enhanced Technology^TM to produce a 2.6 μm solid-core material with a very tight particle size distribution. The particles in the columns are not fully porous but instead have a solid silica core surrounded by a porous outer layer. The very tight particle size distribution results in columns with high permeability. Therefore, bar for bar, the columns produce improved separation efficiency when compared to fully porous materials. The columns are suited for biopharma, pharmaceutical, environmental, bioanalysis, and food and beverage applications.

The compendium technical notes cover the following topics: an overview of the core enhanced technology used in the columns that enable fast, high efficiency HPLC analysis plus the theory and benefits of solid core particles; pressure factors in the columns; comparison of reversed-phase selectivity of the columns; comparison of column performance and impact of particle diameter; and, comparison of chromatographic resolution of solid core columns to fully porous columns. 

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Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with revenues of $17 billion and 50,000 employees in 50 countries. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Our four premier brands – Thermo Scientific, Life Technologies, Fisher Scientific and Unity Lab Services – offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support.

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