TAP
Biosystems, (the new corporate identity of The Automation Partnership), a
leading supplier of innovative automation and consumables for life science
applications, is delighted to announce it has installed a 48 bioreactor version
of its advanced micro bioreactor system (ambr
TM) system in one of Europe's
largest pharma companies. The system will assist in predicting how
antibody-expressing cell lines will behave in large scale bioreactors.
The
ambr system, which closely replicates the characteristics of bioreactors at
micro scale (10-15 ml working volume), was purchased by this major European
pharma, following an on-site evaluation of ambr using their antibody-expressing
CHO cell lines. The system was chosen after their process development
scientists demonstrated scalability of culture performance between ambr,
laboratory and manufacturing scale bioreactors.
The
ambr 48 system can investigate the effects of 48 different combinations of cell
line and culture conditions. It also enables testing of up to four different
temperature and stirrer speeds in just one real-time run, with significantly
less operator time than it would require to perform similar experiments in lab
scale bioreactors. The company now plans to use ambr to help select the best
antibody clones for use in production runs.
Dr
Ralph von Strandmann, TAP Biosystems' European Sales Manager explained: "With
the increasing interest in developing biosimilars and antibody drugs in Europe, progressive pharma companies in this region
recognise that our ambr technology can provide a substantial competitive
advantage in reducing time to trial."
Dr
von Strandmann concluded: "We are pleased that this leading European pharma has
chosen the ambr 48 system to help select optimum clones and culture conditions.
Their confidence shows that other biopharm companies looking to shorten their
therapeutic antibody development timelines can also benefit from accessing the
ambr technology."
For further information visit
www.tapbiosystems.com
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