Sartorius Stedim
Biotech, a leading supplier of the biopharmaceutical industry, launches
UniVessel® SU , a
single-use bioreactor with 2 L working volume. UniVessel® SU is suitable for
mammalian, insect and plant cell culture. Typical applications range from
small-scale protein expression to media or process optimization studies.
UniVessel® SU is irradiated prior to delivery and ready-to-use out of the box.
It is designed to the same safety standards which are required for classical
multi-use bioreactors. The complete culture vessel is disposed after use thus
reducing cleaning time and eliminating autoclaving and re-installation hassle
as well as the risk of cross-contamination.
Design of
UniVessel® SU
The
single-use culture vessel with 2L maximum working volume includes everything to
get started immediately. It is perfectly suitable for cell culture applications
in research, development and production. The single-use vessel can be connected
to all Sartorius BIOSTAT® benchtop bioreactor controllers as well as other
controllers for conventional glass reactors. When working with existing
systems, classical pH and DO sensors as well as Pt100 temperature probes can be
inserted via top plate ports.
Made of USP class VI conform polycarbonate, the UniVessel® SU includes several
ports for media addition, sampling, harvesting as well as spare ports for
insertion of classical sensors or other equipment suitable for pg 13,5 ports.
3-blade segment impellers and a L-sparger provide optimal conditions for use in
cell culture applications. The torospherical bottom as well as the height /
diameter ratio of the UniVessel® SU are similar to the design of the classical
glass UniVessel®. All tubings for media transfer are made of thermoweldable
tubing and feature common Luer or MPC connectors for fast and easy connection
to peripheral equipment. Four feet at the vessel bottom provide for a secure
stand of the vessel when handled, for example, under a laminar flow cabinet.
Additionally, the vessel comes with a stainless steel vessel holder for a safe
support stand when the vessel is in operation. Midisart® BV air filters for
sparger and overlay inlet as well as the gas outlet provide sterile operation
conditions over a long period of time. Temperature control is performed by a
heating blanket and a filter heater is included to ensure long operation times
of the exhaust filter.
Single-use from vessel to sensor
Single-use sensors
for optical measurement of pH and dissolved oxygen (DO) are available and allow
for easy, safe and contamination-free measurement together with the BIOSTAT®
B-DCU II benchtop controller.
All single-use sensors are pre-calibrated. The calibration data are displayed
as barcode on the vessel label and can be transferred via a barcode reader
directly into the BIOSTAT® B-DCU II controller. Already used in other
single-use cell culture devices by Sartorius Stedim Biotech, this well-known
principle of non-invasive pH and DO measurement is now also available with
small-scale single-use bioreactors.
For further information visit
www.sartorius-stedim.com/univessel-su
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