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A new brochure from Malvern Instruments details the range of detectors available for Gel Permeation/Size Exclusion Chromatography (GPC/SEC).

It also provides scientists with the background required to choose the detector array most appropriate to maximizing information flow and experimental productivity. Available as standalone units, or as part of a fully integrated Viscotek multi-detection GPC/SEC system, Malvern’s GPC/SEC detectors provide highly accurate analysis of polymer and protein macromolecular features, such as molecular weight, and combine to offer advanced insight into molecular structure.

GPC/SEC is a central analytical technique for protein and polymer analysis because of its ability to measure defining characteristics. These include molecular weight, molecular weight distribution, molecular size and structure. Malvern’s range of detectors includes light scattering, refractive index (RI), viscometry and UV technology.

RI and UV detectors measure the concentration of the material eluting from the column. Light scattering detectors, in combination with a concentration detector, enable the direct measurement of absolute molecular weight without the need for calibration standards.  Adding a viscometer to the detector array provides sensitive and detailed information about structural features and behavior, such as degree of polymer branching or the aggregation behavior of proteins.

The new brochure takes a practical and technical look at each of the Viscotek GPC/SEC detectors, including Malvern’s comprehensive range of static and dynamic light scattering detectors. Incorporating three static light scattering systems – right angle light scattering (RALS), low angle light scattering (LALS) and the recently launched multi angle light scattering (MALS) – Malvern’s detector range is unsurpassed. Furthermore, it allows the company to offer users an unbiased choice of technology for every GPC/SEC challenge.

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