Channels

 

Special Offers & Promotions

 

 

Latest News

 

 

View Channel

New Products

 

 

View Channel

Video Presentations

 

 

View Channel

Separation Science

 

 

View Channel

Microscopy & Image Analysis

 

 

View Channel

Laboratory Automation & IT Solutions

 

 

View Channel

 

The National Institute for Public Health and the Environment in the Netherlands Uses the Magritek Spinsolve Benchtop NMR System to Investigate Illegal Drugs

publication date: Jul 12, 2017
 | 
author/source: Magritek

Magritek, a leading provider of compact NMR and MRI instruments, reports on how the National Institute of Public Health and the Environment in the Netherlands utilises Magritek’s Spinsolve 60 benchtop NMR to quantitatively investigate illicit medicinal products. 

Magritek Spinsolve 60 spectrometer at RIVMDr Peter Keizers is a scientist in the Centre for Health Protection at RIVM, the Dutch National Institute for Public Health and the Environment based in Bilthoven. As a chemist, he investigates (illegal) drugs, medical devices and other medicinal products. His group studies the composition of these products and specifically look for active pharmaceutical ingredients, preferably in a quantitative way. 

In order to identify components in medicinal products, selective analytical methods are required. NMR spectroscopy is such a technique. Furthermore, NMR spectroscopy offers a direct way to quantify any of the components encountered without the need of a reference standard. Historically we have used and will continue to use high field NMR spectroscopy, various forms of vibration spectroscopy as well as mass spectrometry coupled to chromatographic systems. 

Dr Keizers comments on the benefits of their using the Spinsolve 60. “Compared to other spectroscopic methods, the Magritek benchtop NMR spectrometer yields spectra with relatively high information content directly related to molecular structure. This aspect is even strengthened by the option to monitor other nuclei than just 1H proton and the ability to perform 2D experiments. Compared to high field NMR spectrometers, the benchtop version is easy to use and maintain. It is also much more economic to run using standard NMR sample tubes and not requiring any cryogens.” 

Dr Keizers' group was recognised in the top three of 36 ideas reviewed by RIVM in their annual Innovation Prize competition. In 2014, he proposed a handheld detection device (infrared spectrometer) to carry out chemical analyses quickly and simply on the spot. For example, this would enable rapid screening in the pre-selection of laboratory samples, or in the field, to screen for party drugs at dance events. He was awarded prize money to develop these ideas in the following year. He has published several papers while at RIVM. For example in 2016, he was lead author in a paper that looked at “The quality of sildenafil active substance of illegal source” which was published in the Journal of Pharmaceutical and Biomedical Analysis. 

Magritek's Spinsolve benchtop NMR spectrometers are supplied worldwide to academics in teaching and research; also to industry for research and reaction monitoring through to quality control use. 


more about magritek


 

 


If you have not logged into the website then please enter your details below.



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

 

Today's Picks

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners

 

Exhibitions & Events